| denaturation |
of nucleic acids represents their conversion from the double-stranded into single-stranded forms, usually by heating (opposite of annealing).
출처: www.molecularpathology.com/pt/re/dmp/fulltext.0001...
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| denaturation |
For proteins, a process in which a protein unravels and loses its native conformation (secondary, tertiary, and quaternary structure), thereby becoming biologically inactive. For DNA, the separation of the two strands of the double helix. Denaturation occurs under extreme conditions of pH, salt concentration, temperature, etc. that affect the weak intramolecular interactions (hydrogen-bonds, other vanderWaals forces, ionic bonds).
출처: www.sbs.utexas.edu/delia/bio212/glossary.htm
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