| osteoporotic marrow defect | Focal osteoporotic bone marrow defect of the jaw; a focal radiolucent defect composed of normal marrow. (05 Mar 2000) |
|---|---|
| Eisenmenger's defect | The combination of ventricular septal defect with pulmonary hypertension and consequent right-to-left shunt through the defect, with or without an associated overriding aorta. Synonym: Eisenmenger's defect, Eisenmenger's disease, Eisenmenger's tetralogy. (05 Mar 2000) |
| endocardial cushion defect | <radiology> Persistence of primitive atrioventricular canal and anomalies of AV valves associated with: Down syndrome: in 25% of Trisomy 21 an ECD is present; in 45% of ECD Trisomy 21 is present, asplenia/polysplenia types: complete (AV canal), partial findings: gooseneck deformity on angiogram, increased pulmonary vascularity, enlarged pulmonary artery, enlarged RV, LV, RA; normal LA (secondary to atrial septal defect) (12 Dec 1998) |
| enzyme defect | A disorder resulting from a deficiency (or functional abnormality) of an enzyme. In 1902 Archibald Garrod first attributed a disease to an enzyme defect: an inborn error of metabolism. Today, newborns are routinely screened for certain enzyme defects such as PKU (phenylketonuria) and galactosaemia, an error in the handling (metabolism) of the sugar galactose. (12 Dec 1998) |
| fibrous cortical defect | A common 1 to 3 cm defect in the cortex of a bone, most commonly the lower femoral shaft of a child, filled with fibrous tissue. Nonosteogenic or nonossifying fibroma by convention refers to lesions greater than 3 cm in diameter. See: nonossifying fibroma. Synonym: nonosteogenic fibroma. (05 Mar 2000) |
| uterine filling defect | <radiology> Technical, bubble, blood clot, mucoid material, congenital fold, pseudoadhesions / ridging -- folds long axis, neoplasm, submucosal leiomyoma, adenoma, endometrial carcinoma, pregnancy-related, pregnancy, molar pregnancy, retained conceptus, polyp, septated uterus, synechiae, IUD, iatrogenic (post-op) (12 Dec 1998) |
| filling defect | Displacement of contrast medium by a space-occupying lesion in a radiographic study of a contrast-filled hollow viscus, such as a polyp on a barium enema; also applied to defects in the otherwise uniform distribution of radionuclide in an organ, such as a metastasis in the liver on a 99mTc-sulfur colloid scan. (05 Mar 2000) |
| filling defect in renal collecting system | <radiology> Common causes: transitional cell carcinoma, blood clot, lucent calculus (urate) less common causes: fungus ball, sloughed papilla, fibroepithelial polyp, invasion by hypernephroma, malakoplakia, vessel impression, metastases (12 Dec 1998) |
| lambdoid suture defect | <radiology> Well-defined lucent lesion, classically unilateral, associated with neurofibromatosis (12 Dec 1998) |
| luteal phase defect | Inadequate function of the corpus luteum that may prevent a fertilized egg from implanting in the uterus or may lead to early pregnancy loss. (09 Oct 1997) |
| affinity column | <investigation> A technique of analytical chemistry used to separate and purify a biological molecule from a mixture, based on the attraction of the molecule of interest to a particular ligand which has been previously attached to a solid, inert substance. The mixture is passed through a column containing the ligand attached to the stationary substance, so that the molecule of interest stays within the column while the rest of the mixture continues through to the end. Then, a different chemical is flushed through the column to detach the molecule from the ligand and bring it out separately from the rest of the mixture. (09 Feb 1998) |
| anterior column | The pronounced, ventrally oriented ridge of gray matter in each half of the spinal cord; it corresponds to the anterior or ventral horn appearing in transverse sections of the cord, and contains the motor neurons innervating the skeletal musculature of the trunk, neck, and extremities. See: gray columns. Synonym: columna anterior. (05 Mar 2000) |
| anterior column of medulla oblongata | An elongated, white prominence on the ventral surface of the medulla oblongata on either side along the anterior median fissure, corresponding to the pyramidal tract. Synonym: pyramis medullae oblongatae, anterior column of medulla oblongata, anterior pyramid. (05 Mar 2000) |
| anterior gray column | The central gray matter of the spinal cord surrounding the central canal. Synonym: substantia intermedia centralis et lateralis, anterior gray column, Stilling's gelatinous substance, substantia gelatinosa centralis. (05 Mar 2000) |
| anterolateral column of spinal cord | The lateral white column of the spinal cord between the lines of exit and entrance of the anterior and posterior nerve roots. Synonym: funiculus lateralis, anterolateral column of spinal cord, lateral funiculus of spinal cord. (05 Mar 2000) |