| guanosine diphosphate mannose | <chemical> A nucleoside diphosphate sugar which can be converted to the deoxy sugar GDPfucose, which provides fucose for lipopolysaccharides of bacterial cell walls. Also acts as mannose donor for glycolipid synthesis. Chemical name: Guanosine 5'-(trihydrogen diphosphate), mono-alpha-D-mannopyranosyl ester (12 Dec 1998) |
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| guanosine diphosphate sugars | Esters formed between the aldehydic carbon of sugars and the terminal phosphate of guanosine diphosphate. (12 Dec 1998) |
| phosphatidylinositol 4,5-diphosphate | <biochemistry> A phosphoinositide present in all eukaryotic cells, particularly in the plasma membrane. It is the major substrate for receptor-stimulated phosphoinositidase c, with the consequent formation of inositol 1,4,5-triphosphate and diacylglycerol, and probably also for receptor-stimulated inositol phospholipid 3-kinase. (12 Dec 1998) |
| poly adenosine diphosphate ribose | <chemical> A polynucleotide formed from NAD in the presence of NAD+ nucleosidase. Chemical name: Adenosine 5'-(trihydrogen diphosphate), P'-5-ester with D-ribose, homopolymer (12 Dec 1998) |
| nucleoside diphosphate | The pyrophosphoric ester of a nucleoside, i.e., a nucleoside in which the H of one of the ribose hydroxyls (usually the 5') is replaced by a pyrophosphoric (diphosphoric) radical; e.g., adenosine 5'-diphosphate. Compare: nucleoside bisphosphate. (05 Mar 2000) |
| nucleoside-diphosphate kinase | <enzyme> A phosphotransferase enzyme that is found in mitochondria and in the soluble cytoplasm of cells. It catalyses reversible reactions of a nucleoside triphosphate, e.g., ATP, with a nucleoside diphosphate, e.g., UDP, to form ADP and UTP. Many nucleoside diphosphates can act as acceptor, while many ribonucleoside triphosphates and deoxyribonucleoside triphosphates can act as a donor. Chemical name: ATP:nucleoside-diphosphate phosphotransferase Registry number: EC 2.7.4.6 (12 Dec 1998) |
| nucleoside-diphosphate sugars | Nucleoside diphosphates linked through the 5'-diphosphoric group with simple or complex carbohydrates; e.g., GDP-mannose, UDP-glucose (UDPG), dTDP-glucosamine. (05 Mar 2000) |
| dehydrodolichyl diphosphate synthetase | <enzyme> Membrane-associated prenyl transferase from rat seminiferous tubules; dependent on t,t-farnesyl diphosphate, isopentenyldiphosphate and divalent cation; also from yeast saccharomyces carlsbergensis; looses its activity in the presence of 0.1% triton x-100 Registry number: EC 2.5.1.- Synonym: long chain polyprenyl diphosphate synthetase, dddp synthetase, dehydrodolichyl diphosphate synthase (26 Jun 1999) |
| deoxynucleoside diphosphate-oligonucleotide deoxynucleotidyl transferase | <chemical> Activated by mg++ Synonym: dndp-deoxynucleotidyl transferase, ddodt (26 Jun 1999) |
| dimethylallyl diphosphate-umbelliferone 6-dimethyltransferase | <enzyme> Catalyses the 6-prenylation of umbelliferone, forming demethylsuberosin Registry number: EC 2.5.1.- Synonym: ddud-transferase (26 Jun 1999) |
| dimethylallyl diphosphate umbelliferone 7-O-dimethyltransferase | <enzyme> Catalyses the 7-o-prenylation of umbelliferone, forming o-prenylumbelliferone Registry number: EC 2.5.1.- Synonym: ddu7-transferase (26 Jun 1999) |
| diphosphate | <chemistry> Two phosphate groups linked by esterification. Released in many of the synthetic steps involving nucleotide triphosphates (e.g. Protein and nucleic acid elongation). Rapid cleavage by enzymes that have high substrate affinity ensures that these reactions are essentially irreversible. (18 Nov 1997) |
| dolichol phosphate glucose-dolichol diphosphate oligosaccharide glucosyltransferase | <enzyme> Can also use dolichol-p-galactose as donor Registry number: EC 2.4.1.- Synonym: dolichol-p-glucose-dolichol-p-p-oligosaccharide glucosyltransferase, dolichol-pp-oligosaccharide glucosyltransferase (ii), dolichol-p-p-oligosaccharide glucosyltransferase (i), dol-p-p-oligosaccharide glycosyltransferase, dppo-glucosyltransferase, dolichyl-p-glucose-man(9)(glcnac)2-pp-dolichol glucosyltransferase (26 Jun 1999) |
| inosine 5'-diphosphate | Inosine esterified at its 5' position with diphosphoric acid. Acronym: IDP (05 Mar 2000) |
| inosine diphosphate | <chemical> Inosine 5'-(trihydrogen diphosphate). An inosine nucleotide containing two phosphate groups esterified to the sugar moiety. Synonym: irpp; inosine pyrophosphate. Chemical name: Inosine 5'-(trihydrogen diphosphate) (12 Dec 1998) |