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inositol-1,4-bisphosphate 4-phosphohydrolase <enzyme> Soluble rat brain enzyme highly specific for inositol 1,4-bisphosphate; does not act on inositol 1-phosphate or inositol 1,4,5-trisphosphate
Registry number: EC 3.1.3.-
Synonym: ibp 4-phosphohydrolase
(26 Jun 1999)
inositol 1-alpha-galactosyltransferase <enzyme> Catalyses conversion of udpgalactose plus myo-inositol to galactinol plus udp
Registry number: EC 2.4.1.123
Synonym: galactinol synthase
(26 Jun 1999)
inositol 3 kinase <enzyme> See phosphatidyl inositol 3 kinase.
(18 Nov 1997)
inositol hexakisphosphate kinase <enzyme> 54-kD enzyme that catalyses formation of diphosphoinositol pentakisphosphate (pp-ip5) from inositol hexakisphosphate; the reverse reaction acts as an ATP synthase
Registry number: EC 2.7.4.-
Synonym: ip(6) kinase
(26 Jun 1999)
inositol lipid A membrane-anchored phospholipid that transduces hormonal signals by stimulating the release of any of several chemical messengers.
(09 Oct 1997)
inositol NAD epimerase <enzyme> Converts myo-inositol to scyllo-inositol and neoinositol; inosose also formed and reverse reaction
Registry number: EC 1.1.1.-
(26 Jun 1999)
inositol O-methyltransferase <enzyme> From mesembryanthemum crystallinum; uses s-adenosyl-l-methionine to methylate myo-inositol to form d-ononitol; monomeric mass 41 kD; has been sequenced
Registry number: EC 2.1.1.-
Synonym: myo-inositol o-methyltransferase, imt1 enzyme
(26 Jun 1999)
inositol pentakisphosphate kinase <enzyme> Has pronounced substrate specificity for d-inositol-1,2,4,5,6-pentakisphosphate which it converts to inositol hexakisphosphate
Registry number: EC 2.7.1.-
Synonym: insp5 kinase
(26 Jun 1999)
inositol phosphates Phosphoric acid esters of inositol. They include mono- and polyphosphoric acid esters, with the exception of inositol hexaphosphate which is phytic acid.
(12 Dec 1998)
inositol polyphosphate 3-phosphatase <enzyme> does not require magnesium and is not inhibited by lithium ions
Registry number: EC 3.1.3.-
Synonym: intp 3-phosphatase
(26 Jun 1999)
inositol polyphosphate 4-phosphatase <enzyme> Hydrolyzes the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate
Registry number: EC 3.1.3.-
Synonym: ins polyp 4-phosphatase, ptdins(3,4)p2 4-phosphatase
(26 Jun 1999)
inositol-tetrakisphosphate 1-kinase <enzyme> A 46 kD enzyme from rat liver
Registry number: EC 2.7.1.-
Synonym: inositol 3,4,5,6-tetrakisphosphate 1-kinase, ins(3,4,5,6)p4 1-kinase
(26 Jun 1999)
inositol triphosphate phosphomonoesterase <enzyme> Human erythrocyte membrane enzyme converts inositol 1,4,5-trisphosphate into inositol 1,4-bisphosphate
Registry number: EC 3.1.3.-
Synonym: intp esterase, triphosphoinositide phosphomonoesterase, inositol triphosphate phosphatase, inositol triphosphate 5-phosphatase
(26 Jun 1999)
inositol trisphosphate Inositol 1, 4, 5 trisphosphate is important as a second messenger. It is released from phosphatidyl inositol bisphosphate by the action of a specific phospholipase C enzyme (PLC_) and binds to and activates a calcium channel in the endoplasmic reticulum.
(18 Nov 1997)
adenosine 3',5'-cyclic monophosphate An activator of phosphorylase kinase and an effector of other enzymes, formed in muscle from ATP by adenylate cyclase and broken down to 5'-AMP by a phosphodiesterase; sometimes referred to as the "second messenger." A related compound (2',3') is also known.
Synonym: cyclic adenylic acid, cyclic AMP, cyclic phosphate.
Acronym: cAMP
(05 Mar 2000)
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