| cyclic albuminuria | A functional albuminuria sometimes observed intermittently in cycles of 12 to 36 hours' duration, chiefly in younger persons; the degree of albuminuria is usually slight. Synonym: recurrent albuminuria. (05 Mar 2000) |
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| cyclic AMP | <molecular biology> 3'5' cyclic ester of AMP. The first second messenger hormone signalling system to be characterised. Generated from ATP by the action of adenyl cyclase that is coupled to hormone receptors by G-proteins (GTP-binding proteins). CAMP activates a specific (cAMP dependent) protein kinase and is inactivated by phosphodiesterase action giving 5'AMP. Also functions as an extracellular morphogen for some slime moulds. (18 Nov 1997) |
| cyclic AMP-dependent protein kinase | Enzymes which attach phosphate groups to the serine or tyrosine amino acids on proteins as a means of regulating the proteins' activity in metabolic reactions. (09 Oct 1997) |
| cyclic AMP-dependent protein kinases | <enzyme> A group of enzymes that are dependent on cyclic AMP and catalyze the phosphorylation of serine or threonine residues on proteins. Registry number: EC 2.7.10.- (12 Dec 1998) |
| cyclic AMP receptor protein | A transcriptional regulator in prokaryotes which, when activated by binding cyclic AMP, acts at several promoters. Cyclic AMP receptor protein was originally identified as a catabolite gene activator protein. It was subsequently shown to regulate several functions unrelated to catabolism, and to be both a negative and a positive regulator of transcription. Cell surface cyclic AMP receptors are not included (cyclic AMP receptors), nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins, which are the regulatory subunits of cyclic AMP-dependent protein kinases. (12 Dec 1998) |
| cyclic cmp | <chemical> Cytidine cyclic 3',5'-(hydrogen phosphate). It is formed in mammalian tissue by the enzymatic conversion of cytidine triphosphate and may play a role in the bioregulation of proliferation of normal and malignant cells. Chemical name: Cytidine, cyclic 3',5'-(hydrogen phosphate) (12 Dec 1998) |
| cyclic compound | Any compound in which the constituent atoms, or any part of them, form a ring. Used mainly in organic chemistry where: 1) numerous compound's contain rings of carbon atoms (carbocyclic compound's) or carbon atoms plus one or more atoms of other types (heterocyclic compound's), usually nitrogen, oxygen, or sulfur; 2) where the atoms in the ring are all of the same element (homocyclic or isocyclic compound); 3) where the ring is saturated or contains nonconjugated double bonds (alicyclic compound), the compound is similar in properties to the corresponding acyclic compound (e.g., cyclohexane resembles hexane); 4) where the ring contains conjugated double bonds in a closed loop in which there are 4n + 2 (where n is an integer) delocalised π electrons (Huckel's rule) (aromatic compound; e.g., benzene, pyridine), it is more stable than the corresponding saturated ring and exhibits unusual chemical properties characteristic of itself and not of other types of rings or of acyclic compound's. These aromatic compounds have the ability to sustain an induced ring current. Synonym: closed chain compound, ring compound. (05 Mar 2000) |
| cyclic esotropia | Periodic convergent strabismus often occurring every 48 hours. Synonym: alternate day strabismus. (05 Mar 2000) |
| cyclic GMP | <molecular biology> 3'5' cyclic ester of GMP. A second messenger generated by guanylyl cyclase. See: ANP, Nitric oxide. (18 Nov 1997) |
| cyclic GMP-dependent protein kinases | <enzyme> A group of enzymes that are dependent on cyclic GMP and catalyses the phosphorylation of serine or threonine residues of proteins. Registry number: EC 2.7.10.- (12 Dec 1998) |
| cyclic GMP sensitive 3'-exoribonuclease | <enzyme> Degradation of newly synthesised RNA in cells of bacillus brevis is mediated primarily by above enzyme Registry number: EC 3.1.14.- Synonym: cgmp-exoribonuclease (26 Jun 1999) |
| cyclic guanosine monophosphate | A cyclic version of the nucleotide guanosine monophosphate. It plays a role in communicating vision from the eyes to the brain. (09 Oct 1997) |
| cyclic haematopoiesis | An autosomal recessive, inherited immunodeficiency of gray collie dogs characterised by overwhelming recurrent bacterial infections, bleeding, and coat colour dilution. Synonym: gray collie syndrome. (05 Mar 2000) |
| cyclic imp | <chemical> Inosine cyclic 3',5'-(hydrogen phosphate). An inosine nucleotide which acts as a mild inhibitor of the hydrolysis of cyclic AMP and cyclic GMP and as an inhibitor of cat heart cyclic AMP phosphodiesterase. Chemical name: Inosine, cyclic 3',5'-(hydrogen phosphate) (12 Dec 1998) |
| cyclic inositol phosphate | 1, 2 cyclic derivatives of inositol phosphatide that are invariably formed during enzymic hydrolysis of phosphatidyl inositol species. Have been proposed as second messengers in hormone activated pathways. (18 Nov 1997) |