| systemic sclerosis | <rheumatology> A multisystem disorder of unknown aetiology. It is characterised by fibrosis (scarring) of the skin, blood vessels and internal organs. Involvement of the gastrointestinal tract, heart, kidneys and lungs is common. (09 Jan 1998) |
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| systemic therapy | <pharmacology> Treatment that reaches and affects cells all over the body. (16 Dec 1997) |
| systemic vascular resistance | An index of arteriolar compliance or constriction throughout the body; equal to the blood pressure divided by the cardiac output. (05 Mar 2000) |
| systemic venous hypertension | Increased pressure in the veins ultimately leading to the right atrium nearly always due to disease of the right heart but occasionally due to blockade of one or both venae cavae. (05 Mar 2000) |
| juvenile chronic arthritis, systemic-onset | See: Juvenile rheumatoid arthritis, systemic-onset (still's disease). (12 Dec 1998) |
| juvenile rheumatoid arthritis, systemic-onset | Also known as systemic-onset juvenile chronic arthritis. Still's disease presents with systemic (bodywide) illness including high intermittent fever, a salmon-coloured skin rash, swollen lymph glands, enlargement of the liver and spleen, and inflammation of the lungs (pleuritis) and around the heart (pericarditis). The arthritis may not be immediately apparent but it does always surface and it may persists long after the systemic symptoms are gone. (12 Dec 1998) |
| lupus erythematosus, systemic | A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterised principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown aetiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of le cells in the blood or bone marrow. (12 Dec 1998) |
| acute cutaneous leishmaniasis | A form of cutaneous leishmaniasis characterised by rural distribution of human cases near infected rodents, particularly communal ground squirrels; characterised by acute rapidly developing dermal lesions that become severely inflamed, with moist necrotizing sores or ulcers that heal in two to eight months after a two to four month incubation period; among nonimmune immigrants, multiple lesions may develop, which heal more slowly and leave disabling or disfiguring scars. A strong delayed hypersensitivity and involvement of immune complexes play a role in necrosis, which is part of the healing process and of the strong specific immunity that follows. Synonym: acute cutaneous leishmaniasis, rural cutaneous leishmaniasis, wet cutaneous leishmaniasis. (05 Mar 2000) |
| administration, cutaneous | The application of suitable drug dosage forms to the skin for either local or systemic effects. (12 Dec 1998) |
| anterior cutaneous branches of intercostal nerves | Medial mammary branches of anterior cutaneous branches of ventral primary rami of thoracic spinal nerves. See: medial mammary branches. (05 Mar 2000) |
| anterior cutaneous branch of iliohypogastric nerve | <anatomy, nerve> Distribution, skin on pubis. Synonym: ramus cutaneus anterior nervi iliohypogastrici, genital branch of iliohypogastric nerve. (05 Mar 2000) |
| anterior cutaneous nerves of abdomen | The ventral primary rami of spinal nerves T7-T11 (seventh to eleventh intercostal nerves), which supply the abdominal as well as the thoracic wall; innervate intercostal, subcostal, serratus posterior inferior, transversus abdominis, external and internal oblique, and rectus abdominis muscles, and provide sensory branches to the periphery of the diaphragm, and parietal pleura and peritoneum. Synonym: rami cutanei anteriores pectoralis et abdominalis nervorum intercostalium, ramus cutaneus anterior (pectoralis et abdominalis) nervorum thoracicorum, anterior cutaneous nerves of abdomen, pectoral and abdominal anterior cutaneous branch of intercostal nerves. (05 Mar 2000) |
| anterior femoral cutaneous nerves | Anterior cutaneous branches of femoral nerve; supplies distal 3/4 of skin and superficial fascia of anterior and medial thigh. Synonym: rami cutanei anteriores nervi femoralis. (05 Mar 2000) |
| anthroponotic cutaneous leishmaniasis | A form of Old World cutaneous leishmaniasis, usually with a prolonged incubation period and confined to urban areas. Synonym: chronic cutaneous leishmaniasis, dry cutaneous leishmaniasis, urban cutaneous leishmaniasis. (05 Mar 2000) |
| candidiasis, cutaneous | Candidiasis of the skin manifested as eczema-like lesions of the interdigital spaces, perleche, or chronic paronychia. (12 Dec 1998) |