| endocardial cushion defect | <radiology> Persistence of primitive atrioventricular canal and anomalies of AV valves associated with: Down syndrome: in 25% of Trisomy 21 an ECD is present; in 45% of ECD Trisomy 21 is present, asplenia/polysplenia types: complete (AV canal), partial findings: gooseneck deformity on angiogram, increased pulmonary vascularity, enlarged pulmonary artery, enlarged RV, LV, RA; normal LA (secondary to atrial septal defect) (12 Dec 1998) |
|---|---|
| enzyme defect | A disorder resulting from a deficiency (or functional abnormality) of an enzyme. In 1902 Archibald Garrod first attributed a disease to an enzyme defect: an inborn error of metabolism. Today, newborns are routinely screened for certain enzyme defects such as PKU (phenylketonuria) and galactosaemia, an error in the handling (metabolism) of the sugar galactose. (12 Dec 1998) |
| fibrous cortical defect | A common 1 to 3 cm defect in the cortex of a bone, most commonly the lower femoral shaft of a child, filled with fibrous tissue. Nonosteogenic or nonossifying fibroma by convention refers to lesions greater than 3 cm in diameter. See: nonossifying fibroma. Synonym: nonosteogenic fibroma. (05 Mar 2000) |
| uterine filling defect | <radiology> Technical, bubble, blood clot, mucoid material, congenital fold, pseudoadhesions / ridging -- folds long axis, neoplasm, submucosal leiomyoma, adenoma, endometrial carcinoma, pregnancy-related, pregnancy, molar pregnancy, retained conceptus, polyp, septated uterus, synechiae, IUD, iatrogenic (post-op) (12 Dec 1998) |
| filling defect | Displacement of contrast medium by a space-occupying lesion in a radiographic study of a contrast-filled hollow viscus, such as a polyp on a barium enema; also applied to defects in the otherwise uniform distribution of radionuclide in an organ, such as a metastasis in the liver on a 99mTc-sulfur colloid scan. (05 Mar 2000) |
| filling defect in renal collecting system | <radiology> Common causes: transitional cell carcinoma, blood clot, lucent calculus (urate) less common causes: fungus ball, sloughed papilla, fibroepithelial polyp, invasion by hypernephroma, malakoplakia, vessel impression, metastases (12 Dec 1998) |
| lambdoid suture defect | <radiology> Well-defined lucent lesion, classically unilateral, associated with neurofibromatosis (12 Dec 1998) |
| luteal phase defect | Inadequate function of the corpus luteum that may prevent a fertilized egg from implanting in the uterus or may lead to early pregnancy loss. (09 Oct 1997) |
| anterior cranial base | The portion of the internal base of the skull, anterior to the sphenoidal ridges and limbus, in which the frontal lobes of the brain rest. Synonym: fossa cranii anterior, anterior cranial base. (05 Mar 2000) |
| anterior cranial fossa | The portion of the internal base of the skull, anterior to the sphenoidal ridges and limbus, in which the frontal lobes of the brain rest. Synonym: fossa cranii anterior, anterior cranial base. (05 Mar 2000) |
| attached cranial section | Craniotomy with a segment of the calvaria and attached soft tissues turned as a flap to expose the cranial cavity. Synonym: attached cranial section, osteoplastic craniotomy. (05 Mar 2000) |
| middle cranial fossa | A butterfly-shaped portion of the internal base of the skull posterior to the sphenoidal ridges and limbus and anterior to the crests of the petrous part of the temporal bones and dorsum sellae; it lodges the temporal lobes of the brain in the lateral portions, and the hypophysis centrally. Synonym: fossa cranii media. (05 Mar 2000) |
| cranial | <anatomy> Pertaining to the cranium or to the anterior (in animals) or superior (in humans) end of the body. Origin: L. Cranialis (18 Nov 1997) |
| cranial arteritis | <pathology> An inflammatory condition of the temporal artery. It is a serious chronic vascular disease, characterised by inflammation of the walls of the blood vessels (vasculitis). The age of affected patients is usually over 50 years of age. It most often involves the carotid artery system, and can lead to blindness or stroke. It can be diagnosed by biopsy of an artery, but there is often a false negative result. Elevation of the erythrocyte sedimentation rate is typical. Treatment is with high dose steroids. Common symptoms include headaches and tenderness over the temple (temporal artery). Can be associated with polymyalgia rheumatica. See: polymyalgia rheumatica. Synonym: cranial arteritis, temporal arteritis (20 Jun 2000) |
| cranial base | The sloping floor of the cranial cavity. It comprises both the external base of skull (external view) and the internal base of skull (internal view). See: internal base of skull. Synonym: basis cranii, cranial base. (05 Mar 2000) |