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familial high density lipoprotein deficiency Familial high {density lipoprotein deficiency}; a heritable disorder of lipid metabolism characterised by almost complete absence from plasma of high density lipoproteins, and by storage of cholesterol esters in foam cells, tonsillar enlargement, an orange or yellow-gray colour of the pharyngeal and rectal mucosa, hepatosplenomegaly, lymph node enlargement, corneal opacity, and peripheral neuropathy; autosomal recessive inheritance.
Synonym: familial high {density lipoprotein deficiency}, Tangier disease.
Origin: G. An-, priv., + alpha, a, + lipoprotein + -aemia, blood
(05 Mar 2000)
flux density <radiobiology> Total amount of a quantity passing through a unit surface area in unit time
See: flux.
(09 Oct 1997)
low density lipoprotein <biochemistry> A lipoprotein substances (combination of a fat and a protein) which acts as a carrier for cholesterol and fats in the bloodstream.
High levels of low density lipoprotein are considered a positive risk factor for the development of coronary artery disease. Less than 130 mg/dl is desirable, 130 to 159 mg/dl is borderline high, over 160 is considered high.
Acronym: LDL
(10 Jan 1998)
low density lipoprotein receptor <biochemistry> A cell surface protein that mediates the endocytosis of low density lipoprotein by cells.
Genetic defects in low density lipoprotein receptors lead to abnormal serum levels of low density lipoprotein and hypercholesterolaemia.
(16 Mar 1998)
low-density lipoprotein receptors Receptors on the surface of cells, especially liver cells, which bind to low density lipoprotein and promote clearance of LDL from the plasma.
(05 Mar 2000)
catheterization, peripheral Insertion of a catheter into a peripheral artery, vein, or airway for diagnostic or therapeutic purposes.
(12 Dec 1998)
peripheral <anatomy> Pertaining to or situated at or near the periphery, situated away from a centre or central structure.
(18 Nov 1997)
peripheral aneurysm A saclike aneurysm springing from one side of an artery, an aneurysm of one of the smaller branches of an artery.
(05 Mar 2000)
peripheral anterior synechia Adhesion of the iris to the posterior surface of the cornea in the angle of the anterior chamber; associated with angle-closure glaucoma.
Synonym: peripheral anterior synechia.
Origin: G. Gonia, angle, + synechis, holding together
(05 Mar 2000)
peripheral arteriosclerosis Arteriosclerosis in any of the vessels beyond the aorta; most often refers to the lower extremities.
(05 Mar 2000)
peripheral blood stem cell transplantation A procedure that is similar to bone marrow transplantation. Doctors remove healthy immature cells (stem cells) from a patient's blood and store them before the patient receives high-dose chemotherapy and possibly radiation therapy to destroy the leukaemia cells. The stem cells are then returned to the patient, where they can produce new blood cells to replace cells destroyed by the treatment.
(12 Dec 1998)
peripheral cataract A cataract in which the opacity affects the cortex of the lens.
Synonym: peripheral cataract.
(05 Mar 2000)
peripheral chemoreceptor The chemoreceptor's in the carotid and aortic bodies that are stimulated by chemical changes in the composition of the blood such as hypoxia.
(05 Mar 2000)
peripheral dysostosis Dysostosis of the metacarpals and metatarsals, accompanied by variable facial features; possibly autosomal dominant inheritance.
(05 Mar 2000)
peripheral facial paralysis A condition that involves the facial nerve (VII cranial nerve) and results in the paralysis of one side of the face. Bell's (facial nerve palsy) can be differentiated from a central (stroke) deficit by the inability to raise the eyebrow on the affected side.
(27 Sep 1997)
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