| C1a | activated first component of complement |
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| C1 INH | inhibitor of first component of complement |
| C2 | second cervical nerve; second cervical vertebra; second component of complement |
| C2a | activated second component of complement |
| C3 | third cervical nerve; third cervical vertebra; third component of complement |
| complement factor h | <chemical> A beta-globulin that binds to complement 3b and makes ic3b (inactivated complement 3b) susceptible to cleavage by complement factor I. Complement factor h also acts as an alternative pathway complement inhibitor by interfering with the binding of properdin factor b to c3b. Chemical name: Complement factor H (12 Dec 1998) |
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| complement factor I | <enzyme> Serine proteinase that acts on ic3b (inactivated complement 3b) to cleave it into c3c and c3dg with the help of a trypsin-like proteolytic enzyme. Complement factor I was formerly called kaf, c3binf, or enzyme 3b inactivator. Registry number: EC 3.4.21.45 (12 Dec 1998) |
| complement fixation | <immunology> Binding of complement as a result of its interaction with immune complexes (the classical pathway) or particular surfaces (alternative pathway). (18 Nov 1997) |
| complement fixation tests | Serologic tests based on inactivation of complement by the antigen-antibody complex (stage 1). Binding of free complement can be visualised by addition of a second antigen-antibody system such as red cells and appropriate red cell antibody (haemolysin) requiring complement for its completion (stage 2). Failure of the red cells to lyse indicates that a specific antigen-antibody reaction has taken place in stage 1. If red cells lyse, free complement is present indicating no antigen-antibody reaction occurred in stage 1. (12 Dec 1998) |
| complement haemolytic activity assay | Usual screening assay for complement. Dilutions of the serum to be tested are added to antibody-coated erythrocytes and the percentage of lysis is measured. The values are expressed by ch50, haemolytic complement units per milliliter, which is the dilution of serum required to lyse 50 percent of the erythrocytes in the assay. (12 Dec 1998) |
| complement inactivators | Serum proteins which act at key sites in the complement sequence to modulate or prevent the progression of the reaction. Absence of these factors leads to uncontrolled activation of the complement system with accompanying disease. (12 Dec 1998) |
| complement membrane attack complex | The assembly of complement plasma glycoproteins c5b, c6, c7, c8, and polymeric c9 as a group on biological membranes. The complex forms transmembrane channels which displace lipid molecules and other constituents, thus disrupting the phospholipid bilayer of target cells leading to cell lysis by osmotic leakage. The formation of the membrane attack complex is the terminal step in the complement cascade. (12 Dec 1998) |
| complement pathway, alternative | The complement activation sequence initiated by the activation of complement factor c3, which is triggered by the interaction of microbial polysaccharides and properdin without participation of an antigen-antibody reaction. (12 Dec 1998) |
| complement pathway, classical | The sequential activation of complement, initiated by antigen-antibody complex and the binding of complement factor c1q to the fc region of the antibody. (12 Dec 1998) |
| complement system | A group of more than 20 serum proteins, some of which can be serially activated and participate in a cascade resulting in cell lysis. (05 Mar 2000) |
| complement unit | The smallest amount (highest dilution) of complement that will cause haemolysis of a unit of red blood cells in the presence of a haemolysin unit. Synonym: alexin unit. (05 Mar 2000) |
| complement-fixation reaction | <immunology> Binding of complement as a result of its interaction with immune complexes (the classical pathway) or particular surfaces (alternative pathway). (18 Nov 1997) |
| complement-fixation test | An immunological test for determining the presence of a particular antigen or antibody when one of the two is known to be present, based on the fact that complement is "fixed" in the presence of antigen and its specific antibody. See: Bordet-Gengou phenomenon. (05 Mar 2000) |
| complement-fixing antibody | Antibody that combines with and sensitises antigen leading to the activation of complement, which may result in cell lysis. Synonym: CF antibody, sensitizing substance. (05 Mar 2000) |
| complemental air | The extra volume of air that can be inspired with maximal effort after reaching the end of a normal, quiet inspiration. Common abbreviation is irv. (12 Dec 1998) |
Synonyms : C2b Complement, Complement 2b, Complement C2b Fragment, Complement Component 2b, C2b Fragment, Complement, C2b, Complement, Complement, C2b, Component 2b, Complement, Fragment, Complement C2b
Synonyms : C3 Complement, C3 Precursor, Complement 3, Complement C3 Precursor, Complement Component 3, Precursor-Complement 3, Pro-C3, Pro-Complement 3, C3 Precursor, Complement, C3, Complement, Complement, C3, Component 3, Complement, Precursor Complement 3, Precursor, C3
Synonyms : Alternative Pathway C3 Convertase, C3 Convertase (C3bBb), C3 Convertase, Alternative Pathway, CVFBb, Complement 3 Convertase, Alternative Pathway, Complement 3b-Associated Factor B-fragment Bb, Complement C3 Convertase, CVFBb
Synonyms : C3 Convertase (C4b2a), Classical C3 Convertase, Classical Pathway C3 Convertase, C3 Convertase, Classical
Synonyms : C 3 Nephritic Factor, C3 Nephritic Factor, Complement 3 Nephritic Factor
| complementarity |
In physics, complementarity is a basic principle of quantum theory, and refers to effects such as the wave-particle duality, in which different measurements made on a system reveal it to have either particle-like or wave-like properties. Niels Bohr is usually associated with this concept; in the orthodox form, it is stated that a quantum mechanical system consisting of a boson or fermion can either behave as a particle or as wave, but never simultaneously as both. ...
Ãâó: en.wikipedia.org/wiki/Complementarity_(physics)
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| complement system |
The complement system is a complex biochemical cascade of the immune system, leading to cytolysis, chemotaxis, opsonization and inflammation, it can mark pathogens for phagocytosis. It consists of more than 35 proteins. 12 which are directly involved in the complement pathways, while the rest have regulatory functions. ...
Ãâó: en.wikipedia.org/wiki/Complement_system
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| complement |
The complement system is a complex biochemical cascade of the immune system, leading to cytolysis, chemotaxis, opsonization and inflammation, it can mark pathogens for phagocytosis. It consists of more than 35 proteins. 12 which are directly involved in the complement pathways, while the rest have regulatory functions. ...
Ãâó: en.wikipedia.org/wiki/Complement_(biology)
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| complementary DNA |
The double-stranded DNA complement of an mRNA sequence; synthesized in vitro from a mature RNA template using reverse transcriptase (to create a single strand of DNA from the RNA template) and DNA polymerase (to create the double-stranded DNA). Preparation of cDNAs is often the first step in cloning DNA sequences of interest. ...
Ãâó: www.fao.org/docrep/003/X3910E/X3910E06.htm
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| complementary genes |
Two or more interdependent genes, such that (in the case of dominant complementarity) the dominant allele from either gene can only produce an effect on the phenotype of an organism if the dominant allele from the other gene is also present; or (in the case of recessive complementarity) only double homozygous recessive show the effect.
Ãâó: www.fao.org/docrep/003/X3910E/X3910E06.htm
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