comp : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

MeSH(Medical Subject Headings) 맞춤 검색 (http://www.nlm.nih.gov) 결과 : 5 페이지: 3

Complement C1 - 새창 The first complement component to act in the activation of CLASSICAL COMPLEMENT PATHWAY. It is a calcium-dependent trimolecular complex made up of three subcomponents: COMPLEMENT C1Q; COMPLEMENT C1R; and COMPLEMENT C1S at 1:2:2 ratios. When the intact C1 binds to at least two antibodies (involving C1q), C1r and C1s are sequentially activated, leading to subsequent steps in the cascade of COMPLEMENT ACTIVATION.
Synonyms : C1 Complement, Complement 1, Complement Component 1, C1, Complement, Complement, C1, Component 1, Complement
Complement C1 Inactivator Proteins - 새창 Serum proteins that inhibit, antagonize, or inactivate COMPLEMENT C1 or its subunits.
Synonyms : C1 Esterase Inhibitor, Complement 1 Esterase Inhibitors, Complement C1 Inactivating Proteins, Complement C1 Inhibiting Proteins, Complement C1 Inhibitor Proteins, Complement C1r Protease Inhibitor Proteins, Complement C1s Esterase Inhibitor Proteins
Complement C1 Inhibitor Protein - 새창 An endogenous serine protease inhibitor (SERPINS). It is a 105-kDA plasma glycoprotein, encoded by C1NH gene and produced primarily by the liver and monocytes. It inhibits a broad spectrum of proteases, including the COMPLEMENT C1R and the COMPLEMENT C1S proteases of the CLASSICAL COMPLEMENT PATHWAY, and the MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. C1-INH-deficient individuals suffer from hereditary ANGIONEUROTIC EDEMA.
Synonyms : C1-INH Protein, C1-Inhibitor Protein, Complement C1-Inhibitor Protein, Plasma Protease C1 Inhibitor, C1 INH Protein, C1 Inhibitor Protein, Protein, C1-INH, Protein, C1-Inhibitor, Protein, Complement C1-Inhibitor
Complement C1q - 새창 A subcomponent of complement C1, composed of six copies of three polypeptide chains (A, B, and C), each encoded by a separate gene (C1QA; C1QB; C1QC). This complex is arranged in nine subunits (six disulfide-linked dimers of A and B, and three disulfide-linked homodimers of C). C1q has binding sites for antibodies (the heavy chain of IMMUNOGLOBULIN G or IMMUNOGLOBULIN M). The interaction of C1q and immunoglobulin activates the two proenzymes COMPLEMENT C1R and COMPLEMENT C1S, thus initiating the cascade of COMPLEMENT ACTIVATION via the CLASSICAL COMPLEMENT PATHWAY.
Synonyms : C1q Complement, Complement 1q, Complement Component 1q, C1q, Complement, Complement, C1q, Component 1q, Complement
Complement C1r - 새창 A 80-kDa subcomponent of complement C1, existing as a SERINE PROTEASE proenzyme in the intact complement C1 complex. When COMPLEMENT C1Q is bound to antibodies, the changed tertiary structure causes autolytic activation of complement C1r which is cleaved into two chains, A (heavy) and B (light, the serine protease), connected by disulfide bonds. The activated C1r serine protease, in turn, activates COMPLEMENT C1S proenzyme by cleaving the Arg426-Ile427 bond. No fragment is released when either C1r or C1s is cleaved.
Synonyms : C1r Complement, Complement 1r, Complement Component 1r, C1r, Complement, Complement, C1r, Component 1r, Complement