| DABP | D site albumin promoter binding protein |
|---|---|
| E* | lesion on the erythrocyte cell membrane at the site of complement fixation |
| FMR | fragile site mental retardation [syndrome]; Friend-Moloney-Rauscher [antigen] |
| fra | fragil [site] |
| FRAXE | X-linked mental retardation-fragile site [syndrome] |
| total cleavage | Cleavage in which the blastomeres are completely separated; the entire egg participates in cell division. Synonym: complete cleavage, total cleavage. (05 Mar 2000) |
|---|---|
| enamel cleavage | The splitting of enamel in a plane parallel to the direction of the enamel rods. (05 Mar 2000) |
| equal cleavage | Cleavage producing blastomeres of like size. (05 Mar 2000) |
| equatorial cleavage | Cleavage in which the plane of cytoplasmic division is at right angles to the axis of the ovum. (05 Mar 2000) |
| yolk cleavage | Segmentation of the vitellus. (05 Mar 2000) |
| unequal cleavage | Cleavage producing blastomeres of different sizes at the two poles. (05 Mar 2000) |
| freeze cleavage | Method of specimen preparation for the electron microscope in which rapidly frozen tissue is cracked so as to produce a fracture plane through the specimen. The surface of the fracture plane is then shadowed by heavy metal vapour, strengthened by a carbon film and the underlying specimen is digested away, leaving a replica that can be picked up on a grid and examined in the transmission electron microscope. The great advantage of the method is that the fracture plane tends to pass along the centre of lipid bilayers and it is therefore possible to get en face views of membranes that reveal the pattern of Integral membrane proteins. The E face is the outer lamella of the plasma membrane viewed as if from within the cell, the P face the inner lamella viewed from outside the cell. Fracture planes also often pass along lines of weakness such as the interface between cytoplasm and membrane, so that outer and inner membrane surfaces can be viewed. Further information about the structure can be revealed by freeze etching. Extremely rapid freezing followed by deep etching has allowed the structure of the cytoplasm to be studied without the artefacts that might be introduced by fixation. (18 Nov 1997) |
| acceptor site | The ribosomal binding site for the aminoacyl-tRNA during protein synthesis. (05 Mar 2000) |
| acceptor splicing site | Boundary between the right end of an intron and the left end of the adjacent exon. Synonym: acceptor splicing site. (05 Mar 2000) |
| active site | <chemistry> A specific region of an enzyme where a substrate binds and catalysis takes place (binding site). (06 May 1997) |
| allosteric site | A specific site on a multi-subunit enzyme or other protein that is not the substrate binding site, but that when reversibly bound by an effector, induces a conformational change in the protein, altering its catalytic or binding properties. (12 Dec 1998) |
| amidation site | <molecular biology> A C terminus consensus sequence, required for C terminus amidation of peptides. Consensus is glycine, followed by 2 basic amino acids (arg or lys). (18 Nov 1997) |
| antibody combining site | <immunology> In immune network theory, an idiotope, an antigenic site of an antibody that is responsible for that antibody binding to an antigenic determinant (epitope). Also used of the site on a ligand molecule to which a cell surface receptor binds. (18 Nov 1997) |
| antigen-binding site | <immunology> In immune network theory, an idiotope, an antigenic site of an antibody that is responsible for that antibody binding to an antigenic determinant (epitope). Also used of the site on a ligand molecule to which a cell surface receptor binds. (18 Nov 1997) |
| antigen-combining site | See: paratope. (05 Mar 2000) |