| chromosome painting | Application of in situ hybridisation to determine chromosomal location of genes using fluorescently tagged probes. (18 Nov 1997) |
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| chromosome pair | Two chromosomes of the full diploid karyotype that are similar in form and function but that usually differ in content, one normally being inherited from each parent and one being transmitted to each progeny; in the heteromorphic sex (in humans, the male), one pair, the sex chromosomes, differ markedly in appearance, content, and function. (05 Mar 2000) |
| chromosome pairing | The process in synapsis whereby homologous chromosome's align opposite each other before disjoining in the formation of the daughter cell; the apposition permits exchange of genetic material in crossing-over. (05 Mar 2000) |
| chromosome puffs | Expansions of particular chromosome regions; sites of RNA syntheses. (05 Mar 2000) |
| chromosome rosette | Right before metaphase, human chromosomes briefly form this single ring structure. (09 Oct 1997) |
| chromosome rosette john jordan | Right before metaphase, human chromosomes briefly form this single ring structure. (09 Oct 1997) |
| chromosome satellite | A small chromosomal segment separated from the main body of the chromosome by a secondary constriction; in humans it is usually associated with the short arm of an acrocentric chromosome. (05 Mar 2000) |
| chromosome segregation | <cell biology> The orderly separation of one copy of each chromosome into each daughter cell at mitosis. (18 Nov 1997) |
| chromosome synapsis | <cell biology> The close apposition of homologous chromosomes before cell division or permanently in giant polytene chromosomes. (18 Nov 1997) |
| chromosome translocation | <cell biology> The fusion of part of one chromosome onto part of another. Largely sporadic and random, there are some translocations at hot spots that occur often enough to be clinically significant. See: Philadelphia translocation. (18 Nov 1997) |
| chromosome walking | A procedure to find and sequence a gene whose approximate position in a chromosome is known by classical genetic linkage studies. Starting with the known sequence of a gene shown by classical genetics to be near to the novel gene, new clones are picked from a genomic library by hybridisation with a short probe generated from the appropriate end of the known sequence. The new clones are then sequenced, new probes generated and the process repeated until the gene of interest is reached. (18 Nov 1997) |
| chromosomes | The self-replicating genetic structures of cells containing the cellular DNA that bears in its proteins. (09 Oct 1997) |
| chromosomes in multiple miscarriages | Couples who have had more than one miscarriage (spontaneous abortion) have about a 5% chance that one member of the couple is carrying a chromsome translocation responsible for the miscarriages. (12 Dec 1998) |
| chromosomes, archaeal | Structures within the nucleus of archaeal cells consisting of or containing DNA, which carry genetic information essential to the cell. (12 Dec 1998) |
| chromosomes, bacterial | Structures within the nucleus of bacterial cells consisting of or containing DNA, which carry genetic information essential to the cell. (12 Dec 1998) |
| odd chromosome | A chromosome existing without its normal homologous chromosome; at the reduction division of gametogenesis an accessory chromosome is likely to be included in one daughter cell and not in the other, but may be lost completely by lagging behind on the equatorial plate. Synonym: monosome, odd chromosome, unpaired allosome, unpaired chromosome. (05 Mar 2000) |
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| telocentric chromosome | <genetics> Chromosome with the centromere located at one end. (18 Nov 1997) |
| translocation chromosome | An anomalous chromosome generated by translocation. Synonym: translocation chromosome. (05 Mar 2000) |
| Y chromosome | <genetics> The small chromosome that is male-determining in most mammal species and found only in the heterogametic sex. Thus in mammals the male has one Y chromosome and one X chromosome. One region of the Y chromosome, the pseudoautosomal region, is homologous to and pairs with the X chromosome. The primary determinant of male sexual development is found on the unpaired, differentiated segment of the Y chromosome. It carries few other genes besides those dictating sperm development and triggering appropriate hormonal output. (18 Nov 1997) |
| yeast artificial chromosome | <molecular biology> A vector system that allows extremely large segments of DNA to be cloned. Useful in chromosome mapping, contiguous yeast artificial chromosomes covering the whole Drosophila genome and certain human chromosomes are available. Acronym: YAC (15 Nov 1997) |
| Z chromosome | <genetics> This is a sex chromosome in certain animals such as chickens and moths. In the Z chromosome karyotype, females are heterogametic, so males are ZZ and females are WZ. (11 May 1997) |
| unpaired chromosome | A chromosome existing without its normal homologous chromosome; at the reduction division of gametogenesis an accessory chromosome is likely to be included in one daughter cell and not in the other, but may be lost completely by lagging behind on the equatorial plate. Synonym: monosome, odd chromosome, unpaired allosome, unpaired chromosome. (05 Mar 2000) |
| lampbrush chromosome | <cell biology> Large chromosomes (as long as 1mm), actually meiotic bivalents, seen during prophase of the extended meiosis in the oocytes of some Amphibia. Segments of DNA form loops in pairs along the sides of the sister chromosomes, giving them a brush like appearance. These loops are not permanent structures but are formed by the unwinding of chromomeres and represent sites of very active RNA synthesis. (27 Jun 1999) |
| late replicating chromosome | A chromosome (often anomalous) that is shown, e.g., by incorporation of a labelled nucleotide, to undergo delayed duplication preliminary to mitosis; formerly used as a means of distinguishing members of a group of chromosome's. (05 Mar 2000) |
| fragile x chromosome | X chromosome with a fragile site associated with a frequent form of mental retardation. The fragile X chromosome was first sighted by Herbert A. Lubs in 1969. The fragile X is also called FRAXA (the second A signifies it was the first FRAgile site found on the X chromosome). It is due a trinucleotide repeat (a recurring motif of 3 bases) in the DNA at that spot. (12 Dec 1998) |
Synonyms : Positioning, Chromosome
Synonyms : Chromosome Segregations, Segregation, Chromosome, Segregations, Chromosome
Synonyms : Chromosome Structure, Structure, Chromosome, Structures, Chromosome
Synonyms : Chromosome Walkings, Walking, Chromosome, Walkings, Chromosome
Synonyms : Chromosome
| chromosome walking |
A technique which produces sets of overlapping DNA clones for studying segments of DNA larger than can be cloned individually. A method for the analysis of large regions of DNA, in which a each end of a large single cloned DNA fragment is used separately to screen recombinant DNA genome library for other clones containing neighbouring sequences.
Ãâó: helios.bto.ed.ac.uk/bto/glossary/c.htm
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| chromosome aberration |
Any type of change in the chromosome structure or number.
Ãâó: helios.bto.ed.ac.uk/bto/glossary/c.htm
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| chromosome |
a structure of compact, intertwined molecules of DNA found in the nucleus of cells which carry the cell's genetic information. Humans normally have 46 chromosomes.
Ãâó: www.aegis.com/pubs/beta/1999/be990414.html
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| chromosome |
This is a structure in the nucleus of a cell composed of deoxyribonucleic acid (DNA) and protein; the chromosome forms the basis of heredity and carries genetic information in DNA in the form of a sequence of nitrogenous bases.
Ãâó: www.bio.hw.ac.uk/edintox/glossall.htm
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| chromosome |
An H-shaped structure inside the cell nucleus made up of tightly coiled strands of genes. Each chromosome is numbered (in humans, 1-46). Genes on chromosome 1, 14, 19, and 21 are associated with Alzheimer
Ãâó: www.alz.org/Resources/Glossary.asp
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