| central bone | A small bone occasionally found at the dorsal aspect of the wrist between the scaphoid, capitate, and trapezoid; it is developed as an independent cartilage in early foetal life but usually becomes fused with the scaphoid; it occurs normally in most monkeys. Synonym: central bone. (05 Mar 2000) |
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| central bone of ankle | A bone of the tarsus on the medial side of the foot articulating with the head of the talus, the three cuneiform bones, and occasionally the cuboid. Synonym: os naviculare, central bone of ankle, os centrale tarsi. (05 Mar 2000) |
| central bradycardia | Bradycardia due to disease of the central nervous system, usually with increased intracranial pressure. (05 Mar 2000) |
| central callus | The callus within the medullary cavity of a fractured bone. Synonym: medullary callus. (05 Mar 2000) |
| central canal | The ependyma-lined lumen (cavity) of the neural tube, the cerebral part of which remains patent to form the ventricles of the brain, while the spinal part in the adult often is reduced to a solid strand of modified ependyma. Synonym: canalis centralis medullae spinalis, central canal of spinal cord, tubus medullaris. Synonym: syringocele. (05 Mar 2000) |
| central canal of spinal cord | The ependyma-lined lumen (cavity) of the neural tube, the cerebral part of which remains patent to form the ventricles of the brain, while the spinal part in the adult often is reduced to a solid strand of modified ependyma. Synonym: canalis centralis medullae spinalis, central canal of spinal cord, tubus medullaris. Synonym: syringocele. (05 Mar 2000) |
| central canal of the vitreous | A minute canal running through the vitreous from the discus nervi optici to the lens, containing in foetal life a prolongation of the central artery of the retina, the hyaloid artery. See: vitreous, hyaloid artery. Synonym: canalis hyaloideus, central canal of the vitreous, Cloquet's canal, Stilling's canal. (05 Mar 2000) |
| central canals of cochlea | Centrally placed channels that convey vessels and nerves to the apical turns of the cochlea. Synonym: canales longitudinales modioli, central canals of cochlea. (05 Mar 2000) |
| central cataract | Congenital cataract limited to the embryonic nucleus. (05 Mar 2000) |
| central cementifying fibroma | <tumour> A microscopic variant of a central ossifying fibroma. (05 Mar 2000) |
| central complex | In an enzyme-catalyzed reaction, the structural complex of the enzyme and all of the enzyme's substrates (or the enzyme with all of the enzyme's products) equivalent to the binary complex for a one-substrate enzyme. Compare: binary complex, Michaelis complex. (05 Mar 2000) |
| central cord syndrome | <syndrome> Quadriparesis most severely involving the distal upper extremities, with or without sensory loss and bladder dysfunction, usually due to ischemia from osteophytic or traumatic compression of the central part of the cervical spinal cord and/or artery. (05 Mar 2000) |
| central core disease | A congenital myopathy characterised by hypotonia, delay of motor development in infancy, and nonprogressive or slowly progressive muscle weakness; on biopsy the central core of muscle fibres stains abnormally, myofibrils are abnormally compact, and there is virtual absence of mitochondria and sarcoplasmic reticulum; histochemically, the cores are devoid of oxidative enzyme, phosphorylase, and ATPase activity; autosomal dominant inheritance, often subclinical. (05 Mar 2000) |
| central core disease of muscle | <neurology> One of the conditions that produces floppy baby syndrome. It causes hypotonia (floppiness) in the newborn baby, slowly progressive muscle weakness, and muscle cramps after exercise. Muscle biopsy shows a key diagnostic finding (absent mitochondria in the centre of many type I muscle fibres). The disease is inherited as a dominant trait. The CCD gene is on chromosome 19 (and involves ryanodine receptor-1). Inheritance: autosomal dominant. (12 Dec 1998) |
| central deafness | Deafness due to disorder of the auditory system of the brainstem or cerebral cortex. (05 Mar 2000) |