| Robison ester dehydrogenase | <enzyme> An NADP+ enzyme that catalyses the dehydrogenation (oxidation) of d-glucose-6-phosphate to 6-phospho-d-glucono-d-lactone, this reaction initiating the Dickens shunt. Deficiency of this enzyme is the commonest disease-causing enzyme defect in humans affecting an estimated 400 million people. The gene for this enzyme is on the X chromosome. Males with the enzyme deficiency develop haemolytic anaemia when red blood cells are exposed to oxidant drugs such as the antimalarial primaquine, the sulfonamide antibiotics or sulfones, naphthalene moth balls, or fava beans. Synonym: Robison ester dehydrogenase, Zwischenferment. Acronym: G6PD (12 Sep 2002) |
|---|---|
| cinnamoyl ester hydrolase | <enzyme> From butyrivibrio fibrisolvens; genbank u44893 Registry number: EC 3.1.1.- Synonym: cini gene product, cinb gene product (26 Jun 1999) |
| phorbol ester | <chemical> Polycyclic compound isolated from croton oil in which two hydroxyl groups on neighbouring carbon atoms are esterified to fatty acids. The commonest of these derivatives is phorbol myristoyl acetate (PMA). Potent co carcinogens or tumour promotors, they are diacyl glycerol analogues and activate protein kinase C irreversibly. (31 Dec 1997) |
| phthalate ester hydrolase | <enzyme> Converts diester into monoester and alcohol Registry number: EC 3.1.1.- Synonym: di-n-butyl phthalate hydrolase, di-n-alkyl phthalate hydrolase (26 Jun 1999) |
| Cori ester | An important intermediate in glycogenesis and glycogenolysis. Synonym: Cori ester. (05 Mar 2000) |
| Harden-Young ester | D-fructose 1,6-bisphosphate;important intermediate in sugar metabolism. (05 Mar 2000) |
| Neuberg ester | <biochemistry> A phosphorylated six-carbon sugar formed in the second step of glycolysis by the action of phosphoglucose isomerase on glucose-6-phosphate. In the third step, fructose 6-phospate and ATP are used to create fructose 1,6-biphosphate, ADP and a free hydrogen with the aid of phosphofructokinase. (08 Mar 2000) |
| ng-nitroarginine methyl ester | <chemical> A non-selective inhibitor of nitric oxide synthase. It has been used experimentally to induce hypertension. Pharmacological action: enzyme inhibitors. (12 Dec 1998) |
| sugar ester | Ester of a sugar with an organic or inorganic acid; e.g., d-glucose-6-phosphate. (05 Mar 2000) |
| isoprenylcysteine methyl ester hydrolase | <enzyme> Acts on proteins post-translationally isoprenylated on a cysteine 3 amino acids in from the carboxy terminus, followed by carboxymethylation Registry number: EC 3.1.1.- Synonym: isoprenylcys methylase (26 Jun 1999) |
| thiol ester | An ester formed from a carboxylic acid and a thiol (i.e., RCO-SR') e.g., acetyl-coenzyme A. (05 Mar 2000) |
| Embden ester | Hexose phosphate;a mixture of d-glucose-6-phosphate and d-fructose 6-phosphate; significant in the understanding of sugar metabolism. (05 Mar 2000) |
| tosylarginine methyl ester | <chemical> N(2)-(p-tolylsulfonyl)-l-arginine, methyl ester. Arginine derivative which is a substrate for many proteolytic enzymes. As a substrate for the esterase from the first component of complement, it inhibits the action of c(l) on c(4). Chemical name: L-Arginine, N2-((4-methylphenyl)sulfonyl)-, methyl ester (12 Dec 1998) |
| tosylarginine methyl ester hydrolase | <enzyme> Protease from sea urchin (arbacia punctulata) eggs; fertilization in the sea urchin is accompanied by the release of this protease from eggs into the surrounding seawater; enzyme uses tame as substrate; used as a measure of trypsin-like activity; tryptase (formerly here) is mast cell tryptase (EC 3.4.21.59) Registry number: EC 3.4.- Synonym: tame hydrolase, tame esterase, esterase a2, n-tosyl-l-arginine methyl ester esterase, tamase, tamase-1 (26 Jun 1999) |
| ester | <chemistry> A general term for any organic molecule produced by combining an acid with an alcohol. A derivative of carboxylic acid (acid with a carboxyl group -COOH) which has the general formula RCOOR, where the R's stand for the same or different aliphatic groups (alkyl groups), aromatic groups (aryl groups), or hydrogen ions. (09 Oct 1997) |