| ligand gated ion channel | A transmembrane ion channel whose permeability is increased by the binding of a specific ligand, typically a neurotransmitter at a chemical synapse. The permeability change is often drastic, such channels let through effectively no ions when shut, but allow passage at up to 10exp7 ions sexp 1 when a ligand is bound. Recently, the receptors for both acetylcholine and GABA have been found to share considerable sequence homology, implying that there may be a family of structurally related ligand gated ion channels. (18 Nov 1997) |
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| benzoylpas calcium | 4-Benzamidosalicylic acid calcium salt;an antituberculous agent. (05 Mar 2000) |
| calcium | <element> An element taken in through the diet that is essential for a variety of bodily functions, such as neurotransmission, muscle contraction and proper heart function. Imbalances of calcium can lead to many health problems and excess calcium in nerve cells can cause their death. (22 May 1997) |
| calcium-45 | <radiobiology> Most easily available of the radioactive calcium-45 isotopes; beta-emitter with a half-life of 162.7 days; used as a tracer. (05 Mar 2000) |
| calcium-47 | <radiobiology> A radioisotope of calcium with a half-life of 4.54 days, used in the diagnosis of disorders of calcium metabolism. (05 Mar 2000) |
| calcium alginate | A topical haemostatic. (05 Mar 2000) |
| calcium aminosalicylate | The calcium salt of p-aminosalicylic acid, with the same uses. (05 Mar 2000) |
| calcium antagonist | calcium channel-blocking agent |
| calcium ATPase | <enzyme> Usually used of the calcium pumping ATPase present in high concentration as an integral membrane protein of the sarcoplasmic reticulum of muscle. This pump lowers the cytoplasmic calcium level and causes contraction to stop. Normal function of the pump seems to require a local phospholipid environment from which cholesterol is excluded. (18 Nov 1997) |
| calcium benzoylpas | Calcium 4-benzamidosalicylate;an antituberculous agent. (05 Mar 2000) |
| calcium-binding protein | <biochemistry> There are two main groups of calcium binding proteins, those that are similar to calmodulin and are called EF hand proteins and those that bind calcium and phospholipid (e.g. Lipocortin) and that have been grouped under the generic name of annexins. Many other proteins will bind calcium, although the binding site usually has considerable homology with the calcium-binding domains of calmodulin. They can act as transport proteins, regulator proteins or activator proteins. There is also a vitamin D-dependent variant which is a protein that plays a fundamental role in the vitamin d mediated transport of calcium in reptiles, amphibians, birds and mammals. It is found in the intestine, kidneys, egg shell gland, brain, and possibly other organs. Its molecular weight is species dependent. (12 May 2002) |
| calcium bromide | Used to meet the same indications as potassium bromide. (05 Mar 2000) |
| calcium-calmodulin-activated histone 3 arginine kinase | <enzyme> From nuclear extracts of dividing and quiescent rat heart endothelial cells; represents a new class of ca-cam-dependent kinases which phosphorylate arg Registry number: EC 2.7.10.- Synonym: ca(2+)-calmodulin-activated histone 3 arg kinase, ca-cam h3 kinase (26 Jun 1999) |
| calcium-calmodulin-dependent phosphodiesterase | <enzyme> Hydrolyzes both cgmp and camp; induced during mitogenesis Registry number: EC 3.1.4.- Synonym: ca-cam-phosphodiesterase, calmodulin-dependent cgmp phosphodiesterase (26 Jun 1999) |
| calcium-calmodulin dependent protein kinase | <enzyme> A calmodulin-dependent enzyme that catalyses the phosphorylation of proteins. This enzyme is also sometimes dependent on calcium. A wide range of proteins can act as acceptor, including vimentin, synapsin, glycogen synthase, myosin light chains, and the microtubule-associated proteins. Registry number: EC 2.7.10.- (12 Dec 1998) |