| 영문 | bone marrow transplantation | 한글 | 골수이식 |
|---|---|---|---|
| 설명 | 환자의 병든 골수 대신 건강한 골수세포를 이식하는 처치-암치료에 방사선요법이나 화학요법을 썼을 경우 그 부작용으로 골수의 기능이 극도로 나빠졌을 때나 또는 백혈병의 경우에 면역요법으로 이용된다. 방법은 건강한 골수액을 채취하여 인산완충액을 섞은 링거액에 부유시켜 여과한 다음 정맥에 주사한다. 주입한 골수가 체내에 착상하여 번식하기 쉽게 할 목적으로 미리 X선을 조사하여 이식받는 환자의 항체기능을 억제해 둘 필요가 있다. 이 조작은 급성 방사능증을 일으키기 때문에 여러 가지 보호치료가 필요하다. 그러나 골수를 이식하면 급성 방사능증을 가볍게 넘길 수 있다고 하여 반대로 방사능을 대량으로 조사받은 사람에게 그 치료법으로 이용되기도 한다. 이식에는 스스로의 골수세포를 미리 채취해 놓고 후에 자신에게 주입하는 자가이식과 일란성쌍둥이의 한쪽에서 골수세포를 주입하는 동계이식 및 조직적합항원이 일치한 타인의 골수세포를 주입하는 동종이식이 있다. 대상병으로 백혈병, 재생불량빈혈, 선천면역결핍증 등이 있다. 일반적으로 강력한 면역억제제의 투여가 필요하다. 부작용으로서는 골수이식 후 이식편대숙주병, 기회감염 등이 있다. |
||
| 영문 | zygomatic bone | 한글 | 광대뼈 |
|---|---|---|---|
| 설명 | 얼굴볼부분의 돌출을 만드는 뼈이며 눈확의 아래 바깥쪽에 위치한다. 대략 마름모꼴이며 위턱뼈, 이마뼈 및 관자뼈의 광대뼈돌기에 끼어 있다. 관자돌기는 뒤쪽으로 돌출하여 관자뼈의 광대뼈돌기와 연결하며 광대뼈활을 만든다. 몸체는 4면이 있으며 아래쪽 내면은 위턱뼈의 광대뼈돌기와 봉합한다. 바깥쪽면에는 광대뼈얼굴구멍이 개구된다. 위쪽 내면은 눈확면이며 광대뼈눈확구멍이 개구된다. 후면은 옆머리면이며 광대뼈 옆머리구멍이 개구된다. 이들 3구멍은 몸체를 관통하는 광대뼈관에 의해 서로 연락되며 광대뼈신경이 지나간다. |
||
| 영문 | bone | 한글 | 뼈, 골 |
|---|---|---|---|
| 설명 | 구성－뼈(뼈조직). 이 조직은 굉장히 단단한 조직으로 뼈모세포에 의해서 생성된다. 뼈모세포가 생성한 이 조직은 뼈세포라는 세포를 동심원모양으로 쌓고 있다. 태아시기에는 모든 뼈가 연골조직으로 되어있다. 이런 연골조직이 발생하면서 점점 칼슘염의 침착에 의해서 뼈조직이 생긴다. 그리고 어린이의 경우에는 뼈끝판(epiphyseal plate)라는 곳이 있는데 이곳도 역시 연골조직으로 되어있어서 지속적으로 연골조직을 만들고 칼슘염의 침착이 생겨서 뼈의 성장이 된다. 양쪽에 넓어진 곳을 뼈끝(epiphysis)라고 하고 막대모양의 중간부분을 뼈몸통(diaphysis)라고 하고 이 양쪽의 이행부위를 뼈몸통끝(metaphysis)라고 한다. 뼈끝과 뼈몸통끝의 경계부위에 어린이에게선 뼈끝판(epiphyseal plate)라는 것이 존재하는데, 이곳은 연골조직으로 되어있으며 뼈의 길이성장에 중요한 역할을 하는 것이다. 어른이 되면 이곳의 연골조직은 모두 골조직으로 변화되어 줄모양의 흔적이 남는데, 이것을 뼈끝선이라고 한다. 긴뼈를 절단해 보면 겉으로는 매우 단단하고 조직이 치밀하고, 그 안쪽에는 겉에 비해서 무르고, 조직이 성긴 곳이 있는 걸 알 수가 있다. 겉의 단단한 곳을 치밀뼈(compact bone) 혹은 겉질뼈(cortical bone)이라고 한다. 여기에는 뼈조직이 동심원 모양을 이루고 치밀하게 배열되어 있고 그 동심원 내부에는 뼈세포가 위치하고 있다. 그리고 동심원의 중간에는 관이 있어서 이곳을 통해서 혈액과 영양분이 공급되는데 이관을 중심관(하버스관)이라고 한다. 그리고 내부에 위치한 성긴 곳을 갯솜뼈(Sponge Bone)이라고 한다. 역시 뼈조직으로 이루어진 곳이지만 그 배열이 치밀뼈에 비해서 성기고 외부의 힘에 대한 저항도 약한 조직이다. 이 조직의 내부에는 혈액의 세포를 생성하는 골수라는 것이 존재한다. 짧은 뼈(short bone)－손목이나 발목에서 볼 수 있는 짧고 모양이 불규칙한 뼈. 납작뼈(flat bone)－머리나 골반의 뼈와 같이 납작한 모양의 뼈. 종자뼈(sesamoid bone)－작고 구형인 뼈. 관절주위에 존재한다. 개개인에 따라서 존재하기도 하고 그렇지 않기도 한다. |
||
| 영문 | bone age | 한글 | 뼈나이, 골연령 |
|---|---|---|---|
| 설명 | 생리적 연령의 일종으로 나이를 더함에 따른 뼈의 성숙도를 평가하여 어린이의 전신발육을 판정하는 것이다. 뼈나이 평가에는 손목뼈나 발목뼈의 X선사진을 바탕으로 각 화골중심의 형태나 수를 평가한다. 손목뼈의 화골개수를 세는 방법은 간단해서 그의 수는 난 해를 포함한 연령과 거의 일치하지만 뼈발육의 지속을 가늠할 수 있다. |
||
| 영문 | bone scan | 한글 | 뼈스캔 |
|---|---|---|---|
| 설명 | 뼈의 무기질은 칼슘과 인산염으로 이루어져 있다. 그래서 뼈에 병터가 있는 경우에는 뼈의 인산염분포나 양이 변화하게 된다. 이것을 이용하여 인산염에다가 방사선을 내보내는 물질을 붙여 환자에게 투여하고 그 물질이 내보내는 방사선을 이용하여 영상을 만들어서 뼈의 전반적인 상태나 병터의 발견에 이용하는 방법을 뼈스캔(bone scan)이라고 한다. |
||
| cancer, kidney | Cancer of the major organ responsible for the removal from the blood of the toxins of body metabolism the kidney. Childhood kidney cancer is different from the adult kidney cancer. The most common symptom of kidney cancer is blood in the urine. The diagnosis of kidney cancer is supported by findings of the medical history and examination, blood, urine, and X-ray tests, and confirmed with a biopsy. Kidney cancer is treated with surgery, embolization, radiation therapy, hormone therapy, biological therapy, or chemotherapy. (12 Dec 1998) |
|---|---|
| cancer, larynx | Cancer of the voice box. The larynx is the voice box located at the top of the windpipe (trachea). Cancer of the larynx occurs most often in people over the age of 55 years. People who stop smoking can greatly reduce their risk of cancer of the larynx. Painless hoarseness can be a symptom of cancer of the larynx. The larynx can be examined with a viewing tube called a laryngoscope. Cancer of the larynx is usually treated with radiation therapy or surgery. Chemotherapy can also be used for cancers that have spread. (12 Dec 1998) |
| cancer, leukaemia | Leukaemia is a cancer of the white blood cells. Leukaemias are grouped by how quickly the disease develops (acute or chronic) as well as by the type of blood cell that is affected. People with leukaemia are at significantly increased risk for developing infections, anaemia, and bleeding. Diagnosis of leukaemia is supported by findings of the medical history and examination, and examining blood under a microscope. Leukaemia cells can be detected and further classified with a bone marrow aspiration and/or biopsy. most patients with leukaemia are treated with chemotherapy. Some patients also may have radiation therapy and/or bone marrow transplantation. (12 Dec 1998) |
| cancer, lung | Cancer of the major organ of respiration the lung. Lung cancer kills more men and women than any other form of cancer. Since the majority of lung cancer is diagnosed at a relatively late stage, only 10% of all lung cancer patients are ultimately cured. Eight out of 10 lung cancers are due to tobacco smoke. Lung cancers are classified as either small cell or non-small cell cancers. Persistent cough and bloody sputum can be symptoms of lung cancer. Lung cancer can be diagnosed based on examination of sputum, or tissue examination with biopsy using bronchoscopy, needle through the chest wall, or surgical excision. (12 Dec 1998) |
| cancer, lymphoma, hodgkin's | A type of lymphoma (cancer of the lymphatic system). The most common symptom of Hodgkin's disease is a painless swelling in the lymph nodes in the neck, underarm, or groin. Hodgkin's disease is diagnosed when abnormal tissue is detected by a pathologist after a biopsy of an enlarged lymph node. Treatment usually includes radiation therapy or chemotherapy. Regular follow-up examinations are important after treatment for Hodgkin's disease. Patients treated for Hodgkin's disease have an increased risk of developing other types of cancer later in life, especially leukaemia. (12 Dec 1998) |
| cancer, lymphoma, non-hodgkin's | A lymphoma is a cancer that develops in the lymphatic system. The most common symptom of non-Hodgkin's lymphomas is a painless swelling in the lymph nodes in the neck, underarm, or groin. Non-Hodgkin's lymphomas are diagnosed with a biopsy of an enlarged lymph node. Follow-up examinations are important after lymphoma treatment. Most relapses occur in the first 2 years after therapy. (12 Dec 1998) |
| cancer, malignant melanoma | A skin cancer that begins in cells called melanocytes that can grow together to form benign (not cancerous) moles. A change in size, shape, or colour of a mole can be a sign of melanoma. Melanoma can be cured if detected early, before spread (metastasis) to other areas of the body. Diagnosis is confirmed with a biopsy of the abnormal skin. Sun exposure can cause skin damage that can lead to melanoma. (12 Dec 1998) |
| cancer, melanoma | A skin cancer that begins in cells called melanocytes that can grow together to form benign (not cancerous) moles. A change in size, shape, or colour of a mole can be a sign of melanoma. It can be cured if detected early, before spread (metastasis) to other areas. Diagnosis is confirmed by a biopsy of the abnormal skin. Sun exposure can cause skin damage that can lead to melanoma. (12 Dec 1998) |
| cancer, multiple myeloma | A bone marrow cancer involving a type of white blood cell called a plasma (or myeloma) cell. The tumour cells can form a single collection (a plasmacytoma) or many tumours (multiple myeloma). Plasma cells are part of the immune system and make antibodies. Because patients have an excess of identical plasma cells, they have too much of one type of antibody. As myeloma cells increase in number, they damage and weaken the bones, causing pain and often fractures. When bones are damaged, calcium is released into the blood leading to hypercalcaemia (excess calcium in the blood) and that causes loss of appetite, nausea, thirst, fatigue, muscle weakness, restlessness, and confusion. Myeloma cells prevent the bone marrow from forming normal plasma cells and other white blood cells important to the immune system so patients may not be able to fight infections. The cancer cells can also prevent the growth of new red blood cells, causing anaemia. Excess antibody proteins and calcium may prevent the kidneys from filtering and cleaning the blood properly Cancer, non-Hodgkin's lymphoma: A lymphoma is a cancer that develops in the lymphatic system. The most common symptom of non-Hodgkin's lymphomas is a painless swelling in the lymph nodes in the neck, underarm, or groin. Non-Hodgkin's lymphomas are diagnosed with a biopsy of an enlarged lymph node. Follow-up examinations are important after lymphoma treatment. Most relapses occur in the first 2 years after therapy. (12 Dec 1998) |
| cancer, myeloma | A bone marrow cancer involving a type of white blood cell called a plasma (or myeloma) cell. The tumour cells can form a single collection (a plasmacytoma) or many tumours (multiple myeloma). Plasma cells are part of the immune system and make antibodies. Because patients have an excess of identical plasma cells, they have too much of one type of antibody. As myeloma cells increase in number, they damage and weaken the bones, causing pain and often fractures. When bones are damaged, calcium is released into the blood leading to hypercalcaemia (too much calcium in the blood) and that causes loss of appetite, nausea, thirst, fatigue, muscle weakness, restlessness, and confusion. Myeloma cells prevent the bone marrow from forming normal plasma cells and other white blood cells important to the immune system so patients may not be able to fight infections. The cancer cells can also prevent the growth of new red blood cells, causing anaemia. Excess antibody proteins and calcium may prevent the kidneys from filtering and cleaning the blood properly. (12 Dec 1998) |
| cancer, oesophagus | Cancer of the swallowing tube that passes from the throat to the stomach. The risk of cancer of the oesophagus is increased by long-term irritation of the oesophagus, such as with smoking, heavy alcohol intake, and Barrett's oesophagitis. Cancer of the oesophagus can cause difficulty and pain with swallowing solid food. Diagnosis of oesophageal cancer can be made by barium X-ray of the oesophagus, and confirmed by endoscopy with biopsy of the cancer tissue. (12 Dec 1998) |
| cancer, oral | Cancer of the mouth area. A sore in the mouth that does not heal can be a warning sign of oral cancer. A biopsy is the only to know whether as abnormal area in the oral cavity is cancer. Oral cancer is caused by tobacco (smoking and chewing) and alcohol use. Surgery to remove the tumour in the mouth is the usual treatment for patients with oral cancer. (12 Dec 1998) |
| cancer, ovarian | Cancer of the egg sac of females (ovary). In women under age 30, most ovarian growths are benign, fluid-filled sacs called cysts. There are several types of ovarian cancer. Symptoms of ovarian cancer can be vague. Detection of ovarian cancer involves physical examination (including pelvic exam), ultrasound, X-ray tests, CA-125 blood test and biopsy of the ovary. (12 Dec 1998) |
| cancer, ovary | Cancer of the egg sac of females. most ovarian growths in women under age 30 are benign, fluid-filled cysts. There are several types of ovarian cancer. Symptoms of ovarian cancer can be vague. Detection of ovarian cancer involves physical examination (including pelvic exam), ultrasound, X-ray tests, CA-125 blood test and biopsy of the ovary. (12 Dec 1998) |
| cancer, pancreas | Cancer of the organ which produces many juices that are important for digesting food as well as hormones, such as insulin and glucagon. Pancreatic cancer has been called a silent disease because early pancreatic cancer usually does not cause symptoms. If the tumour blocks the common bile duct and bile cannot pass into the digestive system, the skin and whites of the eyes may become yellow, and the urine darker as a result of accumulated bile pigment called bilirubin. This condition is referred to as jaundice. (12 Dec 1998) |