| coenzyme | <biochemistry> An organic nonprotein molecule, frequently a phosphorylated derivative of a water soluble vitamin, that binds with the protein molecule (apoenzyme) to form the active enzyme (holoenzyme). (18 Nov 1997) |
|---|---|
| coenzyme A | <biochemistry> A derivative of adenosine triphosphate and pantothenic acid that can carry acyl groups (usually acetyl) as thioesters. Involved in many metabolic pathways, for example citric acid cycle and in fatty acid oxidation. (18 Nov 1997) |
| coenzyme a ligases | <enzyme> Enzymes that catalyze the formation of acyl-CoA derivatives. Registry number: EC 6.2.1. (12 Dec 1998) |
| coenzyme a-transferases | <enzyme> Enzymes which transfer coenzyme a moieties from acyl- or acetyl-CoA to various carboxylic acceptors forming a thiol ester. Enzymes in this group are instrumental in ketone body metabolism and utilization of acetoacetate in mitochondria. Registry number: EC 2.8.3 (12 Dec 1998) |
| coenzyme B12 | <biochemistry> A coenzyme derived from cobalamine which is involved in carbon skeletal rearrangements. It is the only biomolecule known that has a carbon-metal bond. (09 Oct 1997) |
| coenzyme F | The active coenzyme form of folic acid; participates in one-carbon metabolism. Synonym: coenzyme F. (05 Mar 2000) |
| coenzyme F420-dependent alcohol dehydrogenase | <enzyme> From methanogenium liminatans; catalyses oxidation of various secondary and cyclic alcohols to the corresponding ketones and the reverse reaction Registry number: EC 1.1.99.- Synonym: f(420) alcohol dehydrogenase (26 Jun 1999) |
| coenzyme F420H2 - 2,3-dimethyl-1,4-naphthoquinone oxidoreductase | <enzyme> Catalyses the reduction of 2,3-dimethyl-1,4-naphthoquinone with reduced coenzyme f420; from archaeoglobus fulgidus; n-terminal amino acid sequence given in first source Registry number: EC 1.6.5.- Synonym: cof(420)h(2) - dmn oxidoreductase, f420h2 - quinone oxidoreductase (26 Jun 1999) |
| coenzyme F(420) reducing hydrogenase | <enzyme> From methanobacterium thermoautotrophicum Registry number: EC 1.12.- Synonym: f420-reducing hydrogenase, 8-hydroxy-5-deazaflavin-reducing hydrogenase, cof(420) reducing hydrogenase, coenzyme f420 hydrogenase (26 Jun 1999) |
| coenzyme factor | <enzyme> An enzyme oxidizing dihydrolipoamide at the expense of NAD+; completes the oxidative decarboxylation of pyruvate; a part of several enzyme complexes (e.g., alpha-ketoglutarate dehydrogenase complex). Decreased activity leads to neuronal loss in brain resulting in psychomotor retardation. Synonym: coenzyme factor, lipoamide dehydrogenase, lipoamide reductase (NADH), lipoyl dehydrogenase. (05 Mar 2000) |
| coenzyme I | An obsolete name for nicotinamide adenine dinucleotide. (05 Mar 2000) |
| coenzyme II | An obsolete for nicotinamide adenine dinucleotide phosphate. (05 Mar 2000) |
| coenzyme M | <biochemistry> 2 mercaptoethane sulphonic acid. This substance is involved in the formation of methane from carbon dioxide by methanogenic bacteria. (18 Nov 1997) |
| coenzyme M-7-merceptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase | <enzyme> From methanobacterium thermoautotrophicum; reduces coenzyme m heterodisulfide of heptanoyl-l-threonine phosphate to yield coenzyme m and 7-mercaptoheptanoyl-l-threonine phosphate; may be a system of 2 enzymes, a hydrogenase and a disulfide reductase Registry number: EC 1.12.99.2 Synonym: heterodisulfide reductase, coenzyme m, coenzyme m heterodisulfide reductase, h2-heterodisulfide oxidoreductase complex, disulfide reductase (com-ss-htp), heterodisulfide reductase (com-ss-htp) (26 Jun 1999) |
| coenzyme Q | Quinones with isoprenoid side chains (specifically, ubiquinones) that mediate electron transfer between cytochrome b and cytochrome c; chemically similar to vitamins E and K, and to other tocopherols, quinones, and tocols. (05 Mar 2000) |