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immunity, natural The capacity of a normal organism to remain unaffected by microorganisms and their toxins. It results from non-specific mechanisms such as genetic endowment, naturally occurring antiviral and bactericidal substances, phagocytosis, and constitutional factors such as body temperature, oxygen tension, and age.
(12 Dec 1998)
infection immunity The paradoxical immune status in which resistance to reinfection coincides with the persistence of the original infection.
Synonym: concomitant immunity.
(05 Mar 2000)
innate immunity This includes local barriers to infection such as skin, stomach acid, mucous, the cough reflex, enzymes in tears and saliva and skin oils.
(27 Sep 1997)
local immunity A natural or acquired immunity to certain infectious agents, as manifested by an organ or a tissue, as a whole or in part.
(05 Mar 2000)
active Characterised by action, not passive, not expectant.
(18 Nov 1997)
active acetate <enzyme> Condensation product of coenzyme A and acetic acid, symbolised as CoAS~COCH3; intermediate in transfer of two-carbon fragment, notably in its entrance into the tricarboxylic acid cycle and in fatty acid synthesis.
This coenzyme plays a huge role in intermediary metabolism, in which cells synthesise, break down or use nutrient molecules for energy production, growth, etc.
Acetyl-coenzyme A synthase is found in bacteria and plants and catalyses the reaction in which acetate enters metabolic pathways and forms acetyl-coenzyme A.
Synonym: acetyl-coenzyme A, active acetate.
(05 Mar 2000)
active aldehyde Any aldehyde derivative of thiamin pyrophosphate.
(05 Mar 2000)
active anaphylaxis Reaction following inoculation of antigen in a subject previously sensitised to the specific antigen, in contrast to passive anaphylaxis.
(05 Mar 2000)
active biomass <cell biology> The amount of a given culture that is actively growing.
(06 May 1997)
active carbon dioxide Activated carbon dioxide, a complex of N-carboxybiotin (biotin + CO2) and an enzyme; the form in which carbon dioxide is added to other molecules in carboxylations; e.g., to methylcrotonyl-CoA to form beta-methylglutaconyl in the catabolism of leucine, and to acetyl-CoA to form malonyl-CoA.
See: acetyl-CoA carboxylase.
(05 Mar 2000)
active caries Microbial-induced lesions of teeth that are increasing in size.
(05 Mar 2000)
active centre The part of a macromolecule at which a substrate or ligand, upon binding, produces biological activity; for an enzyme, this is the catalytic centre, the site on an enzyme that catalyses the reaction.
(05 Mar 2000)
active congestion Congestion due to an increased flow of arterial blood to a part.
(05 Mar 2000)
active electrode A small electrode whose exciting effect is used to stimulate or record potentials from a localised area.
Synonym: exciting electrode, localizing electrode, therapeutic electrode.
(05 Mar 2000)
active formaldehyde A hydroxymethyl derivative of tetrahydrofolate or thiamin pyrophosphate, N5,N10-methylenetetrahydrofo late.
(05 Mar 2000)
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