| antigens, CD58 | <immunology> Glycoproteins with a wide distribution on haematopoietic and non-haematopoietic cells and strongly expressed on macrophages. Cd58 mediates cell adhesion by binding to CD2 (antigens, CD2) and this enhances antigen-specific T-cell activation. (12 Dec 1998) |
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| antigens, CD59 | <immunology> Small glycoproteins found on both haematopoietic and non-haematopoietic cells. Cd59 restricts the cytolytic activity of homologous complement by binding to c8 and c9 and blocking the assembly of the membrane attack complex. (12 Dec 1998) |
| antigens, CD7 | <immunology> Differentiation antigens expressed on pluripotential haematopoietic cells, most human thymocytes, and a major subset of peripheral blood T-lymphocytes. They have been implicated in integrin-mediated cellular adhesion and as signalling receptors on T-cells. (12 Dec 1998) |
| antigens, CD8 | <immunology> Differentiation antigens found on thymocytes and on cytotoxic and suppressor T-lymphocytes. Cd8 antigens are members of the immunoglobulin supergene family and are associative recognition elements in major histocompatibility complex class I-restricted interactions. (12 Dec 1998) |
| antigens, CD80 | <immunology> The natural ligand for the T-cell antigen CD28 (antigens, CD28) mediating t-cell and B-cell adhesion. Cd80 is expressed on activated B-cells and gamma-interferon-stimulated monocytes. The binding of CD80 to CD28 and ctla-4 provides a co-stimulatory signal to T-cells and leads to greatly upregulated lymphokine production. (12 Dec 1998) |
| antigens, CD95 | <immunology> Differentiation antigens expressed on a variety of cell lines including myeloid and lymphoblastoid cell lines. Their primary role is to regulate peripheral immune responses, which is achieved by triggering apoptosis. (12 Dec 1998) |
| antigens, differentiation | Antigens expressed primarily on the membranes of living cells during sequential stages of maturation and differentiation. As immunologic markers they have high organ and tissue specificity and are useful as probes in studies of normal cell development as well as neoplastic transformation. (12 Dec 1998) |
| antigens, differentiation, b-lymphocyte | Membrane antigens associated with maturation stages of B-lymphocytes, often expressed in tumours of B-cell origin. (12 Dec 1998) |
| antigens, differentiation, myelomonocytic | Surface antigens expressed on myeloid cells of the granulocyte-monocyte-histiocyte series during differentiation. Analysis of their reactivity in normal and malignant myelomonocytic cells is useful in identifying and classifying human leukaemias and lymphomas. (12 Dec 1998) |
| antigens, differentiation, t-lymphocyte | Antigens expressed on the cell membrane of T-lymphocytes during differentiation, activation, and normal and neoplastic transformation. Their phenotypic characterization is important in differential diagnosis and studies of thymic ontogeny and T-cell function. (12 Dec 1998) |
| antigens, fungal | Substances of fungal origin that have antigenic activity. (12 Dec 1998) |
| antigens, helminth | Any part or derivative of a helminth that elicits an immune reaction. The most commonly seen helminth antigens are those of the schistosomes. (12 Dec 1998) |
| antigens, heterophile | Antigens stimulating the formation of, or combining with heterophile antibodies. They are cross-reacting antigens found in phylogenetically unrelated species. (12 Dec 1998) |
| antigens, human platelet | Human alloantigens expressed only on platelets, specifically on platelet membrane glycoproteins. These platelet-specific antigens are immunogenic and can result in pathological reactions to transfusion therapy. (12 Dec 1998) |
| antigens, ly | A group of lymphocyte surface antigens differentially located on subpopulations of mouse lymphocytes. This localization has been useful in distinguishing different functional subpopulations of lymphocytes. For example, cytotoxic T-cells bear primarily lyt-23 on their surface and not lyt-1, whereas helper cells bear lyt-1 and not lyt-23. (12 Dec 1998) |
| HTLV-I antigens | Antigens associated with the HTLV-I virus. (12 Dec 1998) |
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| HTLV-II antigens | Antigens associated with the HTLV-II virus. (12 Dec 1998) |
| Hu antigens | he antigens |
| human leukaemia-associated antigens | Antigen's on the surface of leukaemic cells which seem not to be present on the surfaces of the same type of normal cells; the myeloblast antigen of acute myelogenous leukaemia found in chronic myelogenous leukaemia is thought to be associated with a "blastic" transformation. (05 Mar 2000) |
| human leukocyte-associated antigens | Proteins on the outer part of body cells that help fight illness. These proteins vary from person to person. Scientists think that people with certain types of HLA antigens are more likely to develop insulin-dependent diabetes.The HLA antigens are also responsible for histocompatibility reactions. (09 Oct 1997) |
| specific antigens | Antigen's that characterise a single genus of microorganisms. (05 Mar 2000) |
| I antigens | A blood group related both to the abo and p systems that includes several different antigens found in most people on erythrocytes, in milk, and in saliva. The antibodies react only at low temperatures. (12 Dec 1998) |
| I region associated antigens | Class II major histocompatibility (MHC) antigens. (18 Nov 1997) |
| O antigens | Tetra and penta saccharide repeat units of the cell walls of gram-negative bacteria. They are a component of lipopolysaccharide. (18 Nov 1997) |
| oncofetal antigens | Tumour-associated antigen's present in foetal tissue but not in normal adult tissue, including alpha-fetoprotein and carcinoembryonic antigen. (05 Mar 2000) |
| T antigens | Tumour antigens associated wtih replication and transformation by certain DNA tumour viruses, including adenoviruses and papovaviruses. See: beta-haemolytic streptococci, tumour antigens. (05 Mar 2000) |
| epstein-barr virus nuclear antigens | Nuclear antigens encoded by epstein-barr virus genes. at least six nuclear antigens have been identified but their mechanism of action and role in B-cell transformation is still unknown. (12 Dec 1998) |
| tumour antigens | Antigens that may be frequently associated with tumours or may be specifically found on tumour cells of the same origin (tumour specific), tumour antigens may also be associated with replication and transformation by certain DNA tumour viruses, including adenoviruses and papovaviruses. Synonym: neoantigens. See: T antigens. (05 Mar 2000) |
| tumour-specific transplantation antigens | Surface antigen's of DNA tumour virus-transformed cells, which elicit an immune rejection of the virus-free cells when transplanted into an animal that has been immunised against the specific cell-transforming virus. (05 Mar 2000) |
| Jk antigens | See Blood Groups appendix. (05 Mar 2000) |
Synonyms : 4-1BB Receptor, CD137 Antigen, TNFRSF9 Receptor, 4 1BB Receptor, 4 1BB Receptors, Antigen, CD137, Receptor, 4-1BB, Receptor, TNFRSF9, Receptors, 4-1BB
Synonyms : CD14 Antigen, CD14 Monocyte Differentiation Antigen, LPS Receptor, Lipoglycan Receptor, Receptor, LPS, Receptor, Lipoglycan
Synonyms : CD146 Antigen, Gicerin, Glycoprotein MUC18, Melanoma Cell Adhesion Molecule, S-Endo 1 Endothelial-Associated Antigen, Antigen, CD146, MUC18, Glycoprotein
Synonyms : Basigin, Basigin Protein, CD147 Antigen, Emmprin, Emmprin Protein, Extracellular Matrix Metalloproteinase Inducer (EMMPRIN), Antigen, CD147
Synonyms : 3-Fucosyl-N-acetyl-lactosamine, 3-Fucosyllactosamine Determinant, CD15 Antigen, Hapten X, Hapten Y, Lewis X Hapten, SSEA 1, SSEA 1 Determinant, 1 Determinant, SSEA, 3 Fucosyl N acetyl lactosamine, 3 Fucosyllactosamine Determinant, Determinant, SSEA 1