| AIP | acute idiopathic pericarditis; acute infectious polyneuritis; acute intermittent porphyria; aldoster... |
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| ARF | acute renal failure; acute respiratory failure; acute rheumatic fever; Addiction Research Foundation... |
| CGD | Chronic Granulomatous Disease; 만성 육아종 질환 |
| NBT test | Nitro-Blue Tetrazolium (dye reduction) test ; Chronic Granulomatous Disease진단에 사용... |
| CDER | Center for Drug Evaluation and Research; chronic granulomatous disease |
| granulomatous rosacea | Papular lesions in rosacea, characterised microscopically by perifollicular granulomas with central necrosis and scattered giant cells. Lupus miliaris disseminatus faciei is probably a form of granulomatous rosacea. Synonym: rosacea-like tuberculid, tuberculoid rosacea. (05 Mar 2000) |
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| chronic granulomatous disease | <disease> Chronic granulomatous disease is usually fatal in childhood, in which the production of hydrogen peroxide by phagocytes does not occur because of a lesion in an NADP dependent oxidase. Catalase negative bacteria are not killed and there is no luminol enhanced chemiluminescence when the cells are tested. The absence of the oxygen dependent killing mechanism is not itself fatal but seriously compromises the primary defense system. at least three separate lesions can cause the syndrome, the commonest being a defect in plasma membrane cytochrome. Acronym: CGD (12 Jan 1998) |
| chronic granulomatous disease of childhood | <radiology> Disorder of phagocytosis, two forms: X-linked recessive, autosomal recessive, usually fatal in childhood, infection by nonpathogenic organisms (catalase positive), pneumonia, osteomyelitis, diarrhoea, abdominal pain Findings: recurrent pneumonia (resolves incompletely, with abscess formation), adenopathy (big hila), hepatosplenomegaly, calcified granulomata in liver, spleen, lymph nodes, gastric antral narrowing (!) Cf: Chediak-Higashi syndrome More info: chronic granulomatous disease (12 Dec 1998) |
| neurocranial granulomatous arteritis | A small vessel giant cell arteritis which affects only intracranial blood vessels, of unknown aetiology, and with diverse clinical manifestations, including those seen with an involving cerebral tumour, and with a lower grade meningitis, leading to infarction of one portion of the cerebrum or cerebellum. (05 Mar 2000) |
| subacute granulomatous thyroiditis | Thyroiditis with round cell (usually lymphocytes) infiltration, destruction of thyroid cells, epithelial giant cell proliferation, and evidence of regeneration; thought by some to be a reflection of a systemic infection and not an example of true chronic thyroiditis. Synonym: de Quervain's thyroiditis, giant cell thyroiditis. (05 Mar 2000) |
| intracranial granulomatous arteritis | A small vessel, giant cell arteritis that affects only intracranial blood vessels, of unknown aetiology, and with diverse clinical manifestations, including those seen with an involving cerebral tumour, and with a low grade meningitis, leading to infarction of one portion of the cerebrum or cerebellum. (05 Mar 2000) |
| enteritis, granulomatous | Crohn's disease by another name, a chronic inflammatory disease of the intestine primarily in the small and large intestines but which can occur anywhere in the digestive system between the mouth and the anus. Named after Burrill Crohn who described the disease in 1932. The disease usually affects persons in their teens or early twenties. It tends to be a chronic, recurrent condition with periods of remission and exacerbation. In the early stages, Crohn's disease causes small scattered shallow crater-like areas (erosions) called apthous ulcers in the inner surface of the bowel. With time, deeper and larger ulcers develop, causinG scarring and stiffness of the bowel and the bowel becomes increasingly narrowed, leading to obstruction. Deep ulcers can puncture holes in the bowel wall, leading to infection in the abdominal cavity (peritonitis) and in adjacent organs.When only the large intestine (colon) is involved, the condition is called Crohn's colitis. When only the small intestine is involved, the condition is called Crohn's enteritis. When only the end of the small intestine (the terminal ileum) is involved, it is termed terminal ileitis. When both the small intestine and the large intestine are involved, the condition is called Crohn's enterocolitis (or ileocolitis). Abdominal pain, diarrhoea, vomiting, fever, and weight loss can be symptoms. Crohn's disease can be associated with reddish tender skin nodules, and inflammation of the joints, spine, eyes, and liver. Diagnosis is by barium enema, barium X-ray of the small bowel, and colonoscopy. Treatment includes medications for inflammation, immune suppression, antibiotics, or surgery. (The disease is also called regional enteritis). (12 Dec 1998) |
| abdomen, acute | Clinical syndrome characterised by abdominal pain of great severity associated with other symptoms and signs, usually those of acute peritonitis, which might well be the result of a ruptured abdominal viscus or a similar abdominal catastrophe requiring urgent surgical operation. (12 Dec 1998) |
| acute | 1. Sharp, poignant. 2. Having a short and relatively severe course. Origin: L. Acutus = sharp (18 Nov 1997) |
| acute abdomen | Any serious acute intra-abdominal condition (such as appendicitis) attended by pain, tenderness, and muscular rigidity, and for which emergency surgery must be considered. Synonym: surgical abdomen. (05 Mar 2000) |
| acute abscess | A recently formed abscess with little or no fibrosis in the wall of the cavity. Synonym: hot abscess. (05 Mar 2000) |
| acute adrenal crisis | <endocrinology> An abrupt life-threatening state which is caused by insufficient production of cortisol by the adrenal gland. A typical finding in Addison's disease. Individuals who have been taking corticosteroids (glucocorticoids) for a prolonged period of time (weeks to months) are at risk for acute adrenal crisis if the medication is stopped abruptly. For this reason, corticosteroid medication are withdrawn slowly on a diminishing dosing schedule. Symptoms include low blood pressure (shock), weakness, headache, vomiting, fever chills, tachycardia and sweating. Treatment includes blood pressure support and intravenous hydrocortisone. (27 Sep 1997) |
| acute adrenocortical insufficiency | Severe adrenocortical insufficiency when an intercurrent illness or trauma causes an increased demand for adrenocortical hormones in a patient with adrenal insufficiency due to disease or use of relatively large amounts of similar hormones as therapy; characterised by nausea, vomiting, hypotension, and frequently hyperthemia, hyponatraemia, hyperkalaemia, and hypoglycaemia; can be fatal if untreated. Synonym: addisonian crisis, adrenal crisis, Bernard-Sergent syndrome. (05 Mar 2000) |
| acute African sleeping sickness | A disease of humans caused by Trypanosoma brucei rhodesiense in eastern Africa from Ethiopia and Uganda south to Zimbabwe; it is clinically similar to Gambian trypanosomiasis but of shorter duration and more acute in form; patients suffer repeated episodes of pyrexia, become anaemic, and die commonly from cardiac failure. Synonym: acute African sleeping sickness, acute trypanosomiasis, East African sleeping sickness, East African trypanosomiasis. (05 Mar 2000) |
| acute alcoholism | A temporary deterioration in mental function, accompanied by muscular incoordination and paresis, induced by the rapid ingestion of alcoholic beverages. Synonym: intoxication. (05 Mar 2000) |