| PT | pain threshold; parathormone; parathyroid; paroxysmal tachycardia; part time; patient; pericardial t... |
|---|---|
| MAP | malignant atrophic papulosis; mandibular angle plane; maturation-activated protein; maximal aerobic ... |
| ST | esotropia; scala tympani; scaphotrapezoid; sclerotherapy; sedimentation time; semitendinosus; sensor... |
| TT | tablet triturate; tactile tension; tendon transfer; test tube; testicular torsion; tetanus toxin; te... |
| TAT | tetanus antitoxin; thematic apperception test; thematic aptitude test; thrombin-antithrombin complex... |
| monocytes, activated killer | Monocytes made cytotoxic by ex vivo incubation with cytokines, especially interferon-gamma. Akm cells are used for adoptive immunotherapy in cancer patients. (12 Dec 1998) |
|---|---|
| platelet endothelial cell activated protease | <enzyme> Degrades casein and fibrinogen; secreted by endothelial cells and activated in the extracellular medium by platelets; not inhibited by serine protease inhibitors, metalloproteinase inhibitors, or cystein protease inhibitors; pH optimum 7.5 Registry number: EC 3.4.99.- Synonym: pecap (26 Jun 1999) |
| DNA-activated protein kinase | <enzyme> Nuclear serine-threonine protein kinase that phosphorylates DNA-binding proteins; may function in cell homeostasis Registry number: EC 2.7.10.- Synonym: DNA-pk, DNA-dependent protein serine-threonine kinase, DNA-dependent protein kinase, scid gene product, xrcc7 gene product (26 Jun 1999) |
| immunologically activated cell | An immunocyte that is in an elevated state of reactivity capable of carrying out an immune response, in contradistinction to an immunologically competent cell. (05 Mar 2000) |
| thiol activated haemolysins | Cytolytic bacterial exotoxins that act by binding to cholesterol in cell membranes and forming ring like complexes that act as pores. SH groups of these toxins must be in the reduced state for the toxin to function. Oxidation (to disulphide bridges) inactivates the toxin. Examples: tetanolysin, streptolysin O, _ toxin, cereolysin. (18 Nov 1997) |
| TNF-IL1-activated protein kinase | <enzyme> Phosphorylates beta casein in vitro; not the same as casein kinase 1 and casein kinase 2; not activated by mitogens, celllular stresses or any other cytokines than il1 and tnf Registry number: EC 2.7.1.- Synonym: tip kinase, beta casein kinase (26 Jun 1999) |
| Fas-activated serine-threonine kinase | <enzyme> Phosphorylates tia-1 during fas-mediated apoptosis; contains proline-rich sh3-binding domains; mw 60-63 kD; genbank x86779 Registry number: EC 2.7.10.- Synonym: fast kinase (26 Jun 1999) |
| killer cells, lymphokine-activated | Cytolytic lymphocytes with the unique capacity of killing natural killer (nk)-resistant fresh tumour cells. They are interleukin-2-activated nk cells that have no MHC (major histocompatibility complex) restriction or need for antigen stimulation. Lak cells are used for adoptive immunotherapy in cancer patients. (12 Dec 1998) |
| fluorescence-activated cell sorter | <technique> Flow cytometry is an emerging technique which holds great promise for the separation, classification and quantitation of blood cells and antibodies which affect blood cells. Complex computerised instruments are used to pass a monocellular stream of cells, platelets or other microscopic particulate elements through a beam of laser light. The cells are categorised first by size and then computer analysed to sort the mixture of cellular elements into cell type by size. Cells are labelled with fluorescent dye and then passed, in suspending medium, through a narrow dropping nozzle so that each cell is in a small droplet. A laser based detector system is used to excite fluorescence and droplets with positively fluorescent cells are given an electric charge. Charged and uncharged droplets are separated as they fall between charged plates and so collect in different tubes. The machine can be used either as an analytical tool, counting the number of labelled cells in a population or to separate the cells for subsequent growth of the selected population. Further sophistication can be built into the system by using a second laser system at right angles to the first to look at a second fluorescent label or to gauge cell size on the basis of light scatter. The great strength of the system is that it looks at large numbers of individual cells and makes possible the separation of populations with, for example: particular surface properties. Tabulation of counted data in conjunction with size analysis enables determination of relative percentages of each specific cellular subset for which monoclonal antibody conjugates are utilised, even when the size of the cell is identical to other subset species. Flow cytometry is a slightly imprecise but common term for the use of the Fluorescence-activated Cell Sorter (FACS). (01 Dec 1998) |
| fluorescence-activated cell sorting | <technique> A technique for separating and sorting cells marked with a fluorescent label based on how much they fluoresce at a particular wavelength. (12 Jan 1998) |
| light-activated resin | A resin which uses visible or ultraviolet light to excite a photoinitiator which interacts with an amine to form free radicals and initiate polymerization. Used mainly in restorative dentistry. Synonym: light-activated resin. (05 Mar 2000) |
| reaction of partial identity | See: gel diffusion precipitin tests in two dimensions. (05 Mar 2000) |
| partial | 1. Of, pertaining to, or affecting, a part only; not general or universal; not total or entire; as, a partial eclipse of the moon. "Partial dissolutions of the earth." 2. Inclined to favor one party in a cause, or one side of a question, more then the other; baised; not indifferent; as, a judge should not be partial. "Ye have been partial in the law." (Mal. Ii. 9) 3. Having a predelection for; inclined to favor unreasonably; foolishly fond. "A partial parent." "Not partial to an ostentatious display." (Sir W. Scott) 4. <botany> Pertaining to a subordinate portion; as, a compound umbel is made up of a several partial umbels; a leaflet is often supported by a partial petiole. Partial differentials, Partial differential coefficients, Partial differentiation, etc. (of a function of two or more variables), the differentials, differential coefficients, differentiation etc, of the function, upon the hypothesis that some of the variables are for the time constant. <mathematics> Partial fractions, the simple tones which in combination form an ordinary tone; the overtones, or harmonics, which, blending with a fundamental tone, cause its special quality of sound, or timbre, or tone colour. See, also, Tone. Origin: F, fr. LL. Partials, fr. L. Pars, gen. Partis, a part; cf. (for sense 1) F. Partiel. See Part. Source: Websters Dictionary (01 Mar 1998) |
| partial adrenocortical insufficiency | Normal basal adrenocortical function with failure of adrenocortical reserve to respond to ACTH stimulation. (05 Mar 2000) |
| partial agglutinin | Immune agglutinin present in an antiserum in lesser concentration than the major agglutinin. Synonym: partial agglutinin. (05 Mar 2000) |