| 영문 | nucleic acid | 한글 | 핵산 |
|---|---|---|---|
| 설명 | 염기, 당, 인산으로 이루어진 뉴클레오티드가 긴 사슬 모양으로 중합된 고분자 물질. 유전이나 단백질 합성을 지배하는 중요한 물질로, 생물의 증식을 비롯한 생명 활동 유지에 중요한 작용을 한다. 구성 당인 오탄당이 리보오스인 리보핵산과 디옥시리보오스인 디옥시리보 핵산으로 나뉜다. 펜토스로서 리보스나 데옥시리보스 어느 한쪽만을 포함하며 전자를 리보핵산(RNA), 후자를 데옥시리보핵산(deoxyribonucleic acid, DNA)이라 부른다. 모두 4종류의 유기염기에 의해 특징지어지며 아데닌, 구아닌 및 시토신은 양자에 공통이다. 티민은 DNA에, 우라실은 RNA에 포함된다. DNA는 주로 핵에 존재하며 형질유전에 그리고 RNA는 세포질속에서 단백질 합성에 관여한다. 섭취된 핵산은 소화관에서 구성분자로까지 가수분해되어 흡수된다. |
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| OASP | organic acid soluble phosphorus |
|---|---|
| SA | salicylic acid; saline [solution]; salt added; sarcoidosis; sarcoma; scalenus anticus; secondary ame... |
| sRNA | soluble ribonucleic acid |
| ABP | actin-binding protein; ambulatory blood pressure; American Board of Pedodontics; American Board of P... |
| CBP | calcium-binding protein; carbohydrate-binding protein; cardiopulmonary bypass; chlorobiphenyl; cobal... |
| acyl carrier protein | <protein> A small (77 peptides long) protein which binds six other enzymes involved in fatty acid synthesis. It was first isolated in E. Coli bacteria. (09 Oct 1997) |
|---|---|
| acyl carrier protein acylase | <enzyme> From E coli Registry number: EC 2.3.1.- Synonym: acp acylase (26 Jun 1999) |
| acyl protein synthetase | <enzyme> Component of the fatty acid reductase complex of luminescent bacteria Registry number: EC 2.3.1.- Synonym: luxe gene product, fatty acyl-protein synthetase (26 Jun 1999) |
| AKT1 protein kinase | <enzyme> Human homolog of v-akt oncogene product Registry number: EC 2.7.10.- Synonym: akt1 protein, human (26 Jun 1999) |
| AMP-activated protein kinase kinase | <enzyme> An endogenous kinase kinase; reactivates the inactive form of AMP-activated protein kinase (AMP-pk); phosphorylates the 63-kD subunit of AMP-pk Registry number: EC 2.7.1.- Synonym: AMP-pk reactivator, hmg CoA reductase kinase kinase (26 Jun 1999) |
| amyloid beta-protein | A 4 kD protein, 39-43 amino acids long, expressed by a gene located on chromosome 21. It is the major protein subunit of the vascular and plaque amyloid filaments in individuals with alzheimer's disease and in aged individuals with trisomy 21 (down syndrome). The protein is found predominantly in the nervous system, but there have been reports of its presence in non-neural tissue. (12 Dec 1998) |
| amyloid beta-protein precursor | A precursor to the amyloid-beta protein (beta/a4). Alterations in the expression of the amyloid beta-protein precursor (abpp) gene, located on chromosome 21, plays a role in the development of the neuropathology common to both alzheimer disease and down syndrome. Abpp is associated with the extensive extracellular matrix secreted by neuronal cells. Upon cleavage, this precursor produces three proteins of varying amino acid lengths: 695, 751, and 770. The beta/a4 (695 amino acids) or beta-amyloid protein is the principal component of the extracellular amyloid in senile plaques found in alzheimer disease, down syndrome and, to a limited extent, in normal aging. (12 Dec 1998) |
| amyloid precursor protein | <protein> Individuals with Alzheimer's disease are characterised by extensive accumulation of amyloid in the brain, referred to as senile plaques. These consist of a core of amyloid fibrils surrounded by dystrophic neurites. The principal component of the amyloid fibrils is B/A4, a peptide derived from the larger APP. The specific role of amyloid protein is unclear but it is thought that amyloid deposits may cause neurons to degenerate. Amyloid deposits also occur in brains of older Down's Syndrome patients. (04 May 1997) |
| amyloid protein | Glycoprotein deposited extracellularly in tissues in amyloidosis. The glycoprotein may either derive from light chain of immunoglobulin (AIO (amyloid of immune origin): 5-18 kD glycoprotein, product of a single clone of plasma cells, the N terminal part of lambda or kappa light chain) or, in what used to be referred to as AUO, amyloid of unknown origin, from serum amyloid A (SAA), one of the acute phase proteins that increases many fold in inflammation. The polypeptides are organised as a _ pleated sheet making the material rather inert and insoluble. Minor protein components are also found. Should be distinguished from _ amyloid deposited in the brain and that is derived from amyloid precursor protein (see amyloidogenic glycoprotein. (18 Nov 1997) |
| amyloid protein aa | A nonimmunoglobulin amyloid isolated from amyloid fibrils deposited in amyloidosis secondary to chronic inflammatory diseases such as rheumatoid arthritis. Antisera to amyloid protein aa have been used to detect a related serum protein saa. (12 Dec 1998) |
| amyloid protein saa | A serum protein believed to be a circulating precursor to amyloid protein aa. It is present in low concentrations in normal sera, but found in much higher concentrations in sera of older persons and in patients with amyloidosis or with diseases known to predispose to amyloidosis. Very high levels of this protein have been reported during acute inflammatory episodes. Antisera to amyloid protein aa cross-react with protein saa. (12 Dec 1998) |
| androgen binding protein | A protein secreted by testicular Sertoli cells along with inhibin and mullerian inhibiting substance. Androgen binding protein probably maintains a high concentration of androgen in the seminiferous tubules. (05 Mar 2000) |
| animal protein factor | <biochemistry> Member of the water soluble B vitamin group, important in the proper function of the nervous system and important in proper carbohydrate, protein and fat metabolism. (27 Sep 1997) |
| antifreeze protein | <protein> This is a protein found in the extracellular fluid of some fish that livein very cold water, it inhibits the formation of ice crystals. (09 Oct 1997) |
| antitermination protein | A protein that permits RNA polymerase to transcribe through certain termination sites. (05 Mar 2000) |