| nevus, spindle cell | A form of pigmented nevus showing intense melanocytic activity around the dermo-epidermal junction. Large numbers of spindle-shaped melanocytes proliferate downward toward the dermis and usually a large amount of pigment is present. It was first described in 1976 and the bulk of patients reported have been young females with the lesions presenting on the thighs. (12 Dec 1998) |
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| nuclear spindle | See: spindle and mitosis. (18 Nov 1997) |
| Krukenberg's spindle | A vertical fusiform area of melanin pigmentation on the posterior surface of the central cornea. (05 Mar 2000) |
| Kuhne's spindle | A fusiform end organ in skeletal muscle in which afferent and a few efferent nerve fibres terminate; it contains from 3 to 10 striated muscle fibres (intrafusal fibres) that are much smaller than the ordinary muscle fibres, are separated from them by a capsule that encloses the organ, and are innervated by the thin axon of a gamma motoneuron (gamma motor fibre); the sensory endings that occur on the intrafusal fibres are either annulospiral or flower spray endings; this sensory end organ is particularly sensitive to passive stretch of the muscle in which it is enclosed. Synonym: Kuhne's spindle, muscle spindle. (05 Mar 2000) |