| poly(3-hydroxyalkenoate)polymerase | <enzyme> Forms polyesters from medium chain length 3-hydroxy fatty acyl-CoA Registry number: EC 2.3.1.- Synonym: pha polymerase, phac1 gene product (26 Jun 1999) |
|---|---|
| poly(3-hydroxyoctanoic acid) depolymerase | <enzyme> From pseudomona fluorescens gk13; hydrolyzes p(3ho) to form mainly the dimeric ester of 3-hydroxyoctanoic acid Registry number: EC 3.1.1.- Synonym: p(3ho) depolymerase (26 Jun 1999) |
| poly A | <biochemistry, molecular biology> Polynucleotide chain consisting entirely of residues of adenylic acid (i.e. The base sequence is AAAA.AAAA). Polyadenylic chains of various lengths are found at the 3' end of most eukaryotic mRNAs, the poly A tail. (11 Jan 1998) |
| poly(A) | 1. <abbreviation> Poly(adenylic acid). 2. Iridoid indole alkaloid isolated from Vinca sp.; may have pharmacological applications; falling in this class are vinblastine and vincristine. 3. Excretion of d-glyceric acid in the urine; found in renal calculi. 4. An inborn error in metabolism resulting in d-glyceric aciduria. 5. A class of basic antibiotic peptides, found in neutrophils, that apparently kill bacteria by causing membrane damage. (05 Mar 2000) |
| poly adenosine diphosphate ribose | <chemical> A polynucleotide formed from NAD in the presence of NAD+ nucleosidase. Chemical name: Adenosine 5'-(trihydrogen diphosphate), P'-5-ester with D-ribose, homopolymer (12 Dec 1998) |
| poly ADP-ribose glycohydrolase | <enzyme> Splits ribose-ribose bonds; glycohydrolase I has a higher molecular weight and is tightly bound to mammalian cell nuclei; glycohydrolase II has lower molecular weight and is found in cytosol Registry number: EC 3.2.1.- Synonym: (ADP-ribose)n glycohydrolase I, (ADP-ribose)n glycohydrolase II (26 Jun 1999) |
| poly A hydrolase | <enzyme> Endoribonuclease and exoribonuclease isolated; specific to poly(a) Registry number: EC 3.1.4.- Synonym: polyadenylase, polyadenylate hydrolase, poly a exonuclease (26 Jun 1999) |
| poly(A) polymerase | <enzyme> An enzyme that catalyses the formation of a poly(adenylic acid) sequence. (05 Mar 2000) |
| poly-a polymerase | <enzyme> An enzyme in the nucleus of acell that adds several adenine nucleotidesto the 3' end of a primarytranscript messenger RNA. (09 Oct 1997) |
| poly A specific exoribonuclease | <enzyme> Acts on 2' or 3'-linked oligoriboadenylates to liberate 5'-AMP Registry number: EC 3.1.13.- Synonym: 2',3'-exoribonuclease, 3'-exoribonuclease (26 Jun 1999) |
| poly(A)-specific ribonuclease | <enzyme> From vigna unguiculata seedlings; bifunctional enzyme responsible for both poly(a)-polymerizing and poly(a)-hydrolyzing activities; removes the poly(a) tail as the first step in degrading mRNA Registry number: EC 3.1.13.4 Synonym: poly(a) nuclease, mRNA poly(a) nuclease, poly(a) ribonuclease (pan), pan2 protein (26 Jun 1999) |
| poly A tail | <molecular biology> A sequence of adenine nucleotides that get added to the 3' end of some primary transcript messenger RNA molecules in eukaryotes during post-transcriptional processing. The added tail is believed to confer stability to the molecule. Histone mRNA do not have poly A tail. The poly A tail is added post transcriptionally to the primary transcript as part of the nuclear processing of RNA yielding hnRNAs with 60-200 adenylate residues in the tail. In the cytoplasm the poly A tail on mRNAs is gradually reduced in length. The function of the poly A tail is not clear but it is the basis of a useful technique for the isolation of eukaryotic mRNAs. The technique uses an affinity column with oligo(u) or oligo(dT) immobilised on a solid support. If cytoplasmic RNA is applied to such a column, poly A rich RNA (mRNA) will be retained. (13 Nov 1997) |
| poly a-u | <chemical> A double-stranded polyribonucleotide comprising polyadenylic and polyuridylic acids and believed to be a stimulant of the immune system through induction of interferon. Pharmacological action: antiviral agents, interferon inducers. Chemical name: 5'-Adenylic acid, homopolymer, complex with 5'-uridylic acid homopolymer (1:1) (12 Dec 1998) |
| poly(beta-D-mannuronate) lyase | <enzyme> Amino acid sequence has been determined for sp1 and sp2 isoenzymes from midgut of wreath shell, turbo cornutus Registry number: EC 4.2.2.3 Synonym: poly(1,4-beta-d-mannuronide)lyase, alginate lyase I, alginate lyase, aly gene product, mannuronate lyase sp1, mannuronate lyase sp2 (26 Jun 1999) |
| poly-beta-glucosaminidase | <enzyme> An enzyme which breaks down chitin, which is a polysaccharide that forms the hard outer shell of arthropods (insects, spiders, crustaceans, etc.), and the cell walls of fungi, and some algae. (09 Oct 1997) |