| X-linked |
Refers to any gene found on the X chromosome or traits determined by such genes. Refers also to the specific mode of inheritance of such genes.
출처: www.dphpc.ox.ac.uk/opcgg/glossary.htm
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| X-linked a. |
a primary X-linked immunodeficiency disorder characterized by absence of circulating B lymphocytes, absence of plasma cells and germinal centers in lymphoid tissues, and very low levels of circulating immunoglobulins. The pathogenic defect appears to be a failure of pre-B cells to differentiate into mature B cells, express surface immunoglobulins, and produce antibody. Patients are unusually prone to bacterial infection and many have symptoms resembling rheumatoid arthritis. Called also Bruton's a. or disease and X-linked hypogammaglobulinemia.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| X-linked g. |
a gene carried on the X chromosome; the corresponding trait, whether dominant or recessive, is always expressed in males, who have only one X chromosome. X linkage is used sometimes synonymously with sex linkage since no genetic disorders have as yet been associated with genes on the Y chromosome.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| X-linked h. |
transmission of a quality or trait located on the X chromosome.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| X-linked i. |
a chronic form of ichthyosis affecting males, transmitted as an X-linked recessive trait and due to deficiency of the microsomal enzyme steryl-sulfatase; it may be present at birth or appear in early infancy. It is characterized by the presence of prominent, very adherent scales, often brown, especially on the neck, extremities, trunk, and buttocks. Corneal opacities that do not interfere with vision are a frequent associated finding; these may occur in minor form in heterozygotic female carriers.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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