| 영문 | gene therapy | 한글 | 유전자요법 |
|---|---|---|---|
| 설명 | 유전병을 치료할 목적으로, 정상적으로 기능하는 단일유전자 혹은 복수유전자를 어떤 기원에서 얻어내어 생세포에 도입하는 것. 유전물질은 유전자삽입 조작에 의해 수용세포에로 도입된다. 즉, 유전자를 끼워 넣은 새로운 세포를 사용하는 치료로서 1980년 미국의 학자가 지중해빈혈환자에게 강행하여 비판을 받았지만, 미국 국립보건연구소는 1990년 9월 아데노신 데아미나아제(adenosine deaminase, ADA) 결핍증 환자의 림프구에 ADA 유전자를 끼워 넣는 치료를 시작한 이래 현재는 암을 포함한 많은 질병들을 치료하는 목적으로 쓰인다. |
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| 영문 | Electric convulsive therapy(ECT) | 한글 | 전기경련요법 |
|---|---|---|---|
| 설명 | 뇌에 전기 자극을 주어 인위적으로 경련을 유발함으로써 정신 병을 치료하는 방법. 전기쇼크요법(electroshock therapy)이라고도 한다. 1938년에 이탈리아의 체를레티와 비니에 의해 시작되었다. 작용기전은 확실치 않으나 뇌의 신진대사, 생화학 및 효소 등에 변화를 일으킨다는 생물학적, 생화학적 학설이 유력하다. 적응증으로 가장 효과적인 병은 우울증으로 특히 여성에서 갱년기에 호발하는 갱년기 우울증, 우울증과 조증(아주 기분이 좋은 상태가 지속되는 정신병)이 일정한 주기를 두고 반복하는 조울증에 잘 쓰이며, 80~90%에서 효과가 있다. |
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| PIVKA | protein induced by vitamin K absence or antagonism |
|---|---|
| UBBC | unsaturated vitamin B12 binding capacity |
| VAD | venous access device; ventricular assist device; vinblastine and dexamethasone; vitamin A deficiency... |
| VDD | atrial synchronous ventricular inhibited [pacemaker]; vitamin D-dependent |
| VDDR | vitamin D-dependent rickets |
| vitamin B5 | Once used to describe biological activities now ascribed to pantothenic acid or nicotinic acid. (05 Mar 2000) |
|---|---|
| vitamin B6 | <biochemistry> Member of the water soluble B vitamin group. Vitamin B6 or pyridoxine, is active in the metabolism of proteins, carbohydrates and fats. It is also a necessary part of haemoglobin synthesis. B6 deficiency results in retarded growth and a peripheral neuropathy. (27 Sep 1997) |
| vitamin B6 deficiency | Member of the water soluble B vitamin group. Vitamin B6 or pyridoxine, is active in the metabolism of proteins, carbohydrates and fats. It is also a necessary part of haemoglobin synthesis. B6 deficiency results in retarded growth and a peripheral neuropathy. (27 Sep 1997) |
| vitamin B6 unit | Potency expressed in terms of weight of pure crystalline pyridoxine. (05 Mar 2000) |
| vitamin B7 | <biochemistry> This vitamin is necessary for the synthesis of various enzymes and actsto reduce blood cholesterol. Adeficiency in this vitamin causes pellagra, which is characterised bydermatitis, diarrhoea, and inflammation of the mucous membranes. (09 Oct 1997) |
| vitamin Bc conjugase | <enzyme> An enzyme catalyzing the hydrolysis of the pteroylpolyglutamic acids to pteroylmonoglutamic acid, with consequent increase in vitamin activity; vitamin Bc is an obsolete term for folic acid. (05 Mar 2000) |
| vitamin b complex | <chemical> A group of water-soluble substances including thiamine, riboflavin, niacin (nicotinic acid), niacinamide (nicotinamide), the vitamin b6 group (including pyridoxine, pyridoxal, pyridoxamine), biotin, pantothenic acid, folic acid, possibly para-aminobenzoic acid, inositol, vitamin b12, and possibly choline. Chemical name: Vitamin B (12 Dec 1998) |
| vitamin BT | <biochemistry> _ Hydroxy _ trimethyl aminobutyric acid. Compound that transports long chain fatty acids across the inner mitochondrial membrane in the form of acyl carnitine. Sometimes referred to as Vitamin Bt or Vitamin B7. (18 Nov 1997) |
| vitamin Bx | A factor in the vitamin B complex, a part of all folic acids and required for its formation; neutralises the bacteriostatic effects of the sulfonamides since it furnishes an essential growth factor for bacteria, the utilization with which the sulfonamides interfere; used as an ultraviolet screen in lotions and creams. Synonym: paraaminobenzoic acid, vitamin Bx. Acronym: PABA (05 Mar 2000) |
| vitamin C | <biochemistry> A water soluble vitamin crucial for the maintenance of connective tissue, wound healing and scar formation. Deficiency is known as scurvy. Symptoms include dry skin, bleeding and swollen gums, bone pains, dental cavities and mouth sores. (27 Sep 1997) |
| vitamin C deficiency | A disease due to the deficiency of vitamin C (ascorbic acid). Symptoms include weakness, anaemia, spongy gums and mucocutaneous bleeding (mouth ulcers). Synonym: scurvy. (27 Sep 1997) |
| vitamin C test | A tourniquet test used to determine presence of vitamin C deficiency or thrombocytopenia; a circle 2.5 cm in diameter, the upper edge of which is 4 cm below the crease of the elbow, is drawn on the inner aspect of the forearm, pressure midway between the systolic and diastolic blood pressure is applied above the elbow for 15 minutes, and a count of petechiae within the circle is made: 10, normal; 10 to 20, marginal zone; over 20, abnormal. See: Rumpel-Leede test. Synonym: capillary resistance test, vitamin C test. (05 Mar 2000) |
| vitamin C unit | The vitamin C activity of 0.05 mg of the standard crystalline levoascorbic acid; 1 mg of crystalline vitamin C provides 20 USP unit's. See: Sherman unit. (05 Mar 2000) |
| vitamin D | <biochemistry> The sunshine vitamin is produced by the body when exposed to UV light. Plays important role in calcium and phosphorus metabolism. Deficiency is known as rickets. Symptoms include soft (weak) and bendable bones, stunted growth, bow legs, chest deformities and knock-knees. (27 Sep 1997) |
| vitamin D2 | <hormone> The vitamin produced by the body when exposed to UV light. Plays important role in calcium and phosphorus metabolism. Deficiency is known as rickets. Symptoms include soft (weak) and bendable bones, stunted growth, bow legs, chest deformities and knock-knees. (27 Sep 1997) |