| 영문 | gene therapy | 한글 | 유전자요법 |
|---|---|---|---|
| 설명 | 유전병을 치료할 목적으로, 정상적으로 기능하는 단일유전자 혹은 복수유전자를 어떤 기원에서 얻어내어 생세포에 도입하는 것. 유전물질은 유전자삽입 조작에 의해 수용세포에로 도입된다. 즉, 유전자를 끼워 넣은 새로운 세포를 사용하는 치료로서 1980년 미국의 학자가 지중해빈혈환자에게 강행하여 비판을 받았지만, 미국 국립보건연구소는 1990년 9월 아데노신 데아미나아제(adenosine deaminase, ADA) 결핍증 환자의 림프구에 ADA 유전자를 끼워 넣는 치료를 시작한 이래 현재는 암을 포함한 많은 질병들을 치료하는 목적으로 쓰인다. |
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| 영문 | Electric convulsive therapy(ECT) | 한글 | 전기경련요법 |
|---|---|---|---|
| 설명 | 뇌에 전기 자극을 주어 인위적으로 경련을 유발함으로써 정신 병을 치료하는 방법. 전기쇼크요법(electroshock therapy)이라고도 한다. 1938년에 이탈리아의 체를레티와 비니에 의해 시작되었다. 작용기전은 확실치 않으나 뇌의 신진대사, 생화학 및 효소 등에 변화를 일으킨다는 생물학적, 생화학적 학설이 유력하다. 적응증으로 가장 효과적인 병은 우울증으로 특히 여성에서 갱년기에 호발하는 갱년기 우울증, 우울증과 조증(아주 기분이 좋은 상태가 지속되는 정신병)이 일정한 주기를 두고 반복하는 조울증에 잘 쓰이며, 80~90%에서 효과가 있다. |
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| BCLP | bilateral cleft of lip and palate |
|---|---|
| CL | capillary lumen; cardiolipin; cell line; centralis lateralis; chemiluminescence; chest and left arm ... |
| CL/CP | cleft lip/cleft palate |
| CLP | chymotrypsin-like protein; cleft lip with cleft palate; paced cycle length |
| CL/P | cleft lip with or without cleft palate |
| lip | 1. One of the two fleshy folds which surround the orifice of the mouth in man and many other animals. In man the lips are organs of speech essential to certain articulations. Hence, by a figure they denote the mouth, or all the organs of speech, and sometimes speech itself. "Thine own lips testify against thee." (Jeb xv. 6) 2. An edge of an opening; a thin projecting part of anything; a kind of short open spout; as, the lip of a vessel. 3. The sharp cutting edge on the end of an auger. 4. <botany> One of the two opposite divisions of a labiate corolla. (b) The odd and peculiar petal in the Orchis family. See Orchidaceous. 5. <zoology> One of the edges of the aperture of a univalve shell. Lip bit, a pod auger. See Auger. Lip comfort, comfort that is given with words only. Lip comforter, one who comforts with words only. Lip labour, unfelt or insincere speech; hypocrisy. Lip reading, the catching of the words or meaning of one speaking by watching the motion of his lips without hearing his voice. Lip salve, a salve for sore lips. Lip service, expression by the lips of obedience and devotion without the performance of acts suitable to such sentiments. Lip wisdom, wise talk without practice, or unsupported by experience. Lip work. Talk. Kissing. Lip make a lip, to drop the under lip in sullenness or contempt. To shoot out the lip, to show contempt by protruding the lip. Origin: OE. Lippe, AS. Lippa; akin to D. Lip, G. Lippe, lefze, OHG. Lefs, Dan. Laebe, Sw. Lapp, L. Labium, labrum. Cf. Labial. Source: Websters Dictionary (01 Mar 1998) |
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| lip and leg ulceration | An infectious disease of sheep characterised by crusted ulcers on the skin of the face, feet, and external genitalia; thought to be caused by the orf virus. Synonym: lip and leg ulceration. (05 Mar 2000) |
| lip bumper | <dentistry> A lip bumper is used to push the molars on your lower jaw back to create more space for other teeth. The lip bumper consists of an arch wire which is attached to a moulded piece of plastic. You mount the arch wire in the buccal tubes on your lower jaw, and plastic piece rests against your lips. When you eat or talk, you push the plastic piece back which pushes on your molars. That pushes your molars back. (08 Jan 1998) |
| lip pits | Malformations of the lip seen in unilateral or bilateral depressions or fistulae. May be hereditary or associated with cleft lip and/or palate. (05 Mar 2000) |
| lip reflex | A pouting movement of the lips provoked in young infants by tapping near the angle of the mouth. (05 Mar 2000) |
| lip sulcus | A furrow between the developing lip and gum. Synonym: labiodental sulcus, lip sulcus, primary labial groove. (05 Mar 2000) |
| lower lip | The muscular fold bounding the opening of the mouth inferiorly. Synonym: labium inferius oris. (05 Mar 2000) |
| low lip line | The lowest position of the lower lip during the act of smiling or voluntary retraction, the lowest position of the upper lip at rest. (05 Mar 2000) |
| acupuncture therapy | Treatment of disease by inserting needles along specific pathways or meridians. The placement varies with the disease being treated. Heat or moxibustion and acupressure may be used in conjunction. (12 Dec 1998) |
| adjuvant therapy | <oncology, pharmacology> Treatment that is added to increase the effectiveness of a primary treatment. In cancer, adjuvant treatment usually refers to chemotherapy, hormonal therapy or radiation therapy after surgery to increase the likelihood of killing all cancer cells. (14 May 1997) |
| alternative therapy | A term given to nonconventional therapy usually given by persons who do not have a medical qualification. (16 Dec 1997) |
| analytic therapy | Short term for psychoanalytic therapy. (05 Mar 2000) |
| Antibody Directed Enzyme Prodrug Therapy | <pharmacology> A method for targeting a drug to a specific tissue, in which the targeting agent and the drug are administered separately. The drug is designed to be inactive (a prodrug) until it is converted by an enzyme, which is the targeting agent. The enzyme is coupled to an antibody that directs it to the tissue of interest. When the enzyme arrives at the tissue, the prodrug is activated only at that site, sparing other tissues from potentially toxic side effects. Acronym: ADEPT (14 Nov 1997) |
| anticoagulant therapy | The use of anticoagulant drugs to reduce or prevent intravascular or intracardiac clotting. (05 Mar 2000) |
| antisense therapy | Use of antisense DNA for the inhibition of translation of a specific gene product for therapeutic purposes. (05 Mar 2000) |