| vaccineation, serum hepatitis | See Vaccination, hepatitis b. (12 Dec 1998) |
|---|---|
| vaccines | Vaccines are microbial preparations of killed or modified microorganisms which can stimulate an immune response in the body in order to prevent future infection with similar microorganism. The smallpox vaccine has totally eliminated the smallpox disease from our planet. (12 Dec 1998) |
| vaccines, attenuated | Live vaccines prepared from microorganisms which have undergone physical adaptation (e.g., by radiation or temperature conditioning) or serial passage in laboratory animal hosts or infected tissue/cell cultures, in order to produce avirulent mutant strains capable of inducing protective immunity. (12 Dec 1998) |
| vaccines, combined | Two or more vaccines in a single dosage form. (12 Dec 1998) |
| vaccines, conjugate | Semisynthetic vaccines consisting of polysaccharide antigens from microorganisms attached to protein carrier molecules. The carrier protein is recognised by macrophages and T-cells thus enhancing immunity. Conjugate vaccines induce antibody formation in people not responsive to polysaccharide alone, induce higher levels of antibody, and show a booster response on repeated injection. (12 Dec 1998) |
| vaccines, DNA | Recombinant DNA vectors encoding antigens administered for the prevention or treatment of disease. The host cells take up the DNA, express the antigen, and present it to the immune system in a manner similar to that which would occur during natural infection. This induces humoral and cellular immune responses against the encoded antigens. The vector is called naked DNA because there is no need for complex formulations or delivery agents; the plasmid is injected in saline or other buffers. (12 Dec 1998) |
| vaccines, inactivated | Vaccines in which the infectious microbial nucleic acid components have been destroyed by chemical or physical treatment (e.g., formalin, beta-propiolactone, gamma radiation) without affecting the antigenicity or immunogenicity of the viral coat or bacterial outer membrane proteins. (12 Dec 1998) |
| vaccines, synthetic | Small synthetic peptides that mimic surface antigens of pathogens and are immunogenic, or vaccines manufactured with the aid of recombinant DNA techniques. The latter vaccines may also be whole viruses whose nucleic acids have been modified. (12 Dec 1998) |
| vaccinia | <dermatology> The cutaneous and sometimes systemic reactions associated with vaccination with smallpox vaccine. (18 Nov 1997) |
| vaccinia gangrenosa | A severe or even fatal form of vaccinia occurring chiefly in subjects with an immunologic deficiency or dyscrasia and characterised by progressive enlargement of the initial and also of secondary lesions. Synonym: vaccinia gangrenosa. (05 Mar 2000) |
| vaccinia virus | <molecular biology, virology> DNA viruses used in several biotechnology applications, including expression vector systems. Because they can hold quite a lot of DNA, they can be used to make more than one protein at once in a cell, which can be useful for making proteins with more than one polypeptide chain. (14 Nov 1997) |
| vaccinial | Relating to vaccinia. (05 Mar 2000) |
| vacciniform | Resembling vaccinia. (05 Mar 2000) |
| vaccinist | 1. A person who vaccinates. Synonym: vaccinist. 2. A scarifier or other instrument used in vaccination. (05 Mar 2000) |
| vaccinium | <botany> A genus of ericaceous shrubs including the various kinds of blueberries and the true cranberries. Origin: L, the blueberry, or whortleberry. Source: Websters Dictionary (01 Mar 1998) |