| CSDB | cat scratch disease bacillus |
|---|---|
| GNB | ganglioneuroblastoma; gram-negative bacillus; guanine nucleotide-binding [protein] |
| HBCG | heat-aggregated Calmette-Guerin bacillus |
| KL | kidney lobe; Klebs-Loeffler [bacillus]; Kleine-Levin [syndrome] |
| TB | Taussig-Bind [syndrome]; terabyte; term birth; terminal bronchiole; terminal bronchus; thromboxane B... |
| diphtheria toxin | <protein> An ab exotoxin (62 kD) coded by _ corynephage of virulent Corynebacterium diphtheriae strains (that can produce a repressor of toxin production). The B subunit binds to receptors on the surface of the target cell and facilitates the entry of the enzymically active A subunit (21 kD) that ADP ribosylates elongation factor 2, thereby halting mRNA translation. (18 Nov 1997) |
|---|---|
| intracellular toxin | <protein> Heat stable polysaccharide like toxin bound to a bacterial cell. The term is used more specifically to refer to lipopolysaccharide (LPS) of the outer membrane of gram-negative bacteria. There are three parts to the molecule, the Lipid A (six fatty acid chains linked to two glucosamine residues), the core oligosaccharide (branched chain of ten sugars) and a variable length polysaccharide side chain (up to 40 sugar units in smooth forms) that can be removed without affecting the toxicity (rough LPS). Some endotoxin is probably released into the medium and endotoxin is responsible for many of the virulent effects of gram-negative bacteria. (18 Nov 1997) |
| t-2 toxin | <chemical> (3 alpha,4 beta,8 alpha)-12,13-epoxytrichothec-9-ene-3,4,8,15-tetrol 4,15-diacetate 8-(3-methylbutanoate). A potent mycotoxin produced in feedstuffs by several species of the genus fusarium. It elicits a severe inflammatory reaction in animals and has teratogenic effects. Chemical name: Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 4,15-diacetate 8-(3-methylbutanoate), (3alpha,4beta,8alpha)- (12 Dec 1998) |
| tetanus toxin | <protein> Neurotoxin released by Clostridium tetani, becomes active when peptide cleaved proteolytically to heavy (100 kD) and light (50 kD) chains held together by disulphide bond. Heavy chain binds to disialogangliosides (GD2 and GD1b) and part of the peptide (the amino terminal B fragment) forms a pore: light chain is a zinc endopeptidase that specifically attacks synaptobrevin, to block neurotransmitters. See: botulinum toxin (18 Nov 1997) |
| toxin | <pharmacology> A poison, frequently used to refer specifically to a protein produced by some higher plants, certain animals and pathogenic bacteria, which is highly toxic for other living organisms. Such substances are differentiated from the simple chemical poisons and the vegetable alkaloids by their high molecular weight and antigenicity. Origin: Gr toxikon = arrow poison, from Gr. Toxikos = of or for a bow (18 Nov 1997) |
| toxin spectrum | A figure in the form of a spectrum used by Ehrlich to represent the neutralizing power of antitoxin in the presence of toxin, toxone, etc. (05 Mar 2000) |
| erythrogenic toxin | <protein> Toxin produced by strains of Streptococcus pyogenes responsible for scarlet fever. Three antigenic variants of the toxin are known. It is a small protein that is complexed with hyaluronic acid and can intensify the effects of other toxins such as endotoxin and streptolysin O. (18 Nov 1997) |
| extracellular toxin | <protein> Toxin released from gram-positive and gram-negative bacteria as opposed to endotoxins that form part of the cell wall. Examples are cholera, pertussis and diphtheria toxins. Usually specific and highly toxic. (18 Nov 1997) |
| Abel's bacillus | Klebsiella pneumoniae subsp. Ozaenae See: Klebsiella ozaenae. (05 Mar 2000) |
| abortus bacillus | A species of the genus brucella whose natural hosts are cattle and other bovidae. Other mammals, including man, may be infected. Abortion and placentitis are frequently produced in the pregnant animal. (12 Dec 1998) |
| acne bacillus | A bacteria isolated from normal skin, intestinal contents, wounds, blood, pus, and soft tissue abscesses. It is a common contaminant of clinical specimens, presumably from the skin of patients or attendants. (12 Dec 1998) |
| bacillus | <bacteria> A genus of bacteria of the family Bacillaceae, including large aerobic or facultatively anaerobic, spore forming, rod shaped cells, the great majority of which are gram-positive and motile. The genus is separated into 48 species, of which three are pathogenic or potentially pathogenic and the remainder are saprophytic soil forms. Many organisms historically called Bacillus are now classified in other genera. (18 Nov 1997) |
| Bacillus amyloliquefaciens | A highly amylolytic species of soil bacteria that produces subtilisin. (05 Mar 2000) |
| bacillus amyloliquifaciens | <bacteria> Bacillus amyloliquifaciens is a Gram-positive, rod-shaped bacterium used to produce alpha-amylase and serine protease. (09 Oct 1997) |
| bacillus anthracis | A species of bacteria that causes anthrax in humans and animals. (12 Dec 1998) |