| haemolytic disease of newborn | <haematology> A condition which develops in the foetus due to an incompatibility between the mother's blood type (RH factor) and the baby's. Maternal antibodies, which enter the foetal circulation during delivery attack the baby's red blood cells leading to haemolysis (rupture of the cells). Symptoms include an infant with an enlarged liver and spleen, swelling, jaundice and anaemia. (27 Sep 1997) |
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| haemolytic disease of the newborn | Abnormal breakup of red blood cells in the foetus or newborn. This is usually due to antibodies made by the mother directed against the baby's red cells. It is typically caused by rh incompatibility, that is differences between the mother and baby uinvolving the rh blood group. (12 Dec 1998) |
| haemorrhagic disease of newborn | A self-limited haemorrhagic disorder of the first days of life, caused by a deficiency of the vitamin k-dependent blood coagulation factors II, vii, ix, and x. (12 Dec 1998) |
| haemorrhagic disease of the newborn | A syndrome characterised by spontaneous internal or external bleeding accompanied by hypoprothrombinaemia, slightly decreased platelets, and markedly elevated bleeding and clotting times, usually occurring between the third and sixth days of life and effectively treated with vitamin K. (05 Mar 2000) |
| hyaline membrane disease of the newborn | A disease seen especially in premature neonates with respiratory distress; characterised postmortem by atelectasis and alveolar ducts lined by an eosinophilic membrane; also associated with reduced amounts of lung surfactant. Synonym: hyaline membrane syndrome, respiratory distress syndrome of the newborn. (05 Mar 2000) |
| spontaneous gangrene of newborn | Gangrene due to vascular occlusion of unknown cause, usually in marasmic or dehydrated infants. (05 Mar 2000) |
| newborn | neonatal, neonate |
| newborn jaundice | <paediatrics> A normal condition of elevated bilirubin in the bloodstream of a newborn. This occurs secondary to immaturity of liver cells (cannot effectively metabolise bilirubin) and the increased destruction of red blood cells (further releasing bilirubin into the bloodstream) that is normally seen in the newborn. The jaundice usually appears between the 2nd and 5th days of life and usually clears by 2 weeks. Other factors which can potentiate jaundice in the newborn include: sepsis, biliary atresia, Rhesus incompatibility, galactosaemia, cephalohaematoma, polycythaemia, G-6-P-D deficiency and congenital rubella, syphilis, toxoplasmosis or cytomegalovirus infection. (10 Jan 1998) |
| newborn screening | Tests of newborns to detect those at increased risk for disorders such as pku (phenylketonuria) and hypothyroidism. (12 Dec 1998) |
| subcutaneous fat necrosis of newborn | Indurated plaques and nodules appearing usually a few days or a few weeks after birth and usually resolving within a few months, characterised microscopically by birefringent needle-shaped crystals within necrotic fat cells; the condition remains localised, unlike sclerema neonatorum. (05 Mar 2000) |
| disease, haemolytic, of the newborn | Abnormal breakup of red blood cells in the foetus or newborn. (12 Dec 1998) |
| infant, newborn | An infant during the first month after birth. (12 Dec 1998) |
| infant, newborn, diseases | Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both hereditary diseases and metabolism, inborn errors are available as general concepts. (12 Dec 1998) |
| jaundice of the newborn | Icterus which can be accentuated by many factors including excessive haemolysis, sepsis, neonatal hepatitis or congenital atresia of the biliary system. Synonym: physiologic icterus, jaundice of the newborn, neonatal jaundice, physiologic jaundice. (05 Mar 2000) |
| leukocytosis of the newborn | An apparently "physiologic" leukocytosis usually observed in newborn infants, in whom the white blood cell counts are usually greater than 10,000 per cu mm, and sometimes range to 45,000 per cu mm, resulting chiefly from increased numbers of neutrophils (especially single and bilobed forms). On the third or fourth day of life, the count generally decreases rapidly, and then fluctuates for several days; beginning about the fourth week of life, a relative lymphocytosis is observed, and this normally continues for a few years. (05 Mar 2000) |