| sex hormone-binding globulin | A glycoprotein migrating as a beta-globulin. Its molecular weight, 52,000 or 95,000-115,000, indicates that it exists as a dimer. The protein binds testosterone, dihydrotestosterone, and estradiol in the plasma. Changes in its concentration significantly affect the ratio of unbound (biologically active) testosterone to estradiol in plasma. (12 Dec 1998) |
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| sex steroid-binding globulin | A protein that transports 65% of the testosterone in plasma. Synonym: sex steroid-binding globulin. (05 Mar 2000) |
| testosterone-oestrogen-binding globulin | A glycoprotein migrating as a beta-globulin. Its molecular weight, 52,000 or 95,000-115,000, indicates that it exists as a dimer. The protein binds testosterone, dihydrotestosterone, and estradiol in the plasma. Changes in its concentration significantly affect the ratio of unbound (biologically active) testosterone to estradiol in plasma. (12 Dec 1998) |
| thyroid binding globulin | <protein> Thyroid binding globulin (TBG) is a plasma protein which binds the majority of thyroid hormone in the bloodstream. Bound thyroid hormone is inactive, only the unbound fraction (0.3%) is considered active. Birth control pills and pregnancy can lead to increased TBG levels in the plasma. Androgens can decrease TBG levels in the plasma. (27 Sep 1997) |
| thyroxine-binding globulin | An alpha-globulin of blood with a strong binding affinity for thyroxine; triiodothyronine is bound to it much less firmly; a deficiency or excess of this protein may occur as a rare benign X-linked disorder. Synonym: thyroxine-binding protein. (05 Mar 2000) |
| cellular immune theory | A concept, put forth by Elie Metchnikoff, that cells, not antibodies, were responsible for the immune response of an organism. (05 Mar 2000) |
| primary immune response | <immunology> The immune response to the first challenge by a particular antigen. Usually less extensive than the secondary immune response, being slower and shorter lived with smaller amounts of lower affinity antibody being produced. (18 Nov 1997) |
| hemic and immune systems | The organs involved in the production and functions of the blood and the cellular and molecular components providing defense against foreign organisms or substances. (12 Dec 1998) |
| secondary immune response | The response of the immune system to the second or subsequent occasion on which it encounters a specific antigen. (18 Nov 1997) |
| human measles immune serum | Obtained from the blood of a healthy person who has survived an attack of measles. Synonym: measles convalescent serum. (05 Mar 2000) |
| human pertussis immune serum | The sterile serum prepared from the pooled blood of healthy adult human beings who have received repeated courses of phase I pertussis vaccine; administered intravenously or intramuscularly for the prophylaxis or treatment of whooping cough. (05 Mar 2000) |
| human scarlet fever immune serum | Scarlet fever convalescent serum, obtained from healthy persons who have survived an attack of scarlet fever. (05 Mar 2000) |
| humoral immune response | <immunology> Those immune responses mediated by antibody. (06 Mar 1998) |
| immune | <immunology> Protected against, infectious disease by either specific or non-specific mechanisms. Origin: L. Immunis = free, exempt (18 Nov 1997) |
| immune adherence | The binding of antigen-antibody complexes or cells coated with antibodies or complement to cells bearing the appropriate complement or Fc receptors. (05 Mar 2000) |