| 영문 | blood | 한글 | 혈액, 피 |
|---|---|---|---|
| 설명 | 순환기, 즉 심장과 혈관 안을 순환하는 유동성의 조직을 말한다. 혈액은 전체 체중의 약 8%를 차지하며, 비중은 1,056~1,059, 점도는 약 4.5, pH는 7.4이다. 혈액은 액체성분인 혈장과 거기에 떠돌고 있는 세포성분으로 구성되어 있다. 혈장은 전체 혈액의 55%를 차지하며 수분, 단백질, 혈당, 지방질, 무기염류, 질소화합물로 이루어진다. 세포성분은 전체 혈액의 45%를 차지하며 적혈구, 백혈구, 혈소판으로 이루어져 있다. 혈액의 주요 기능은 전신 조직으로 산소와 영양분 같은 필요한 물질을 운반하며 불필요한 물질을 배설기관으로 운반하는 일이다. 그 밖에 생체에 해로운 물질이나 세균을 제거하고, 내부환경의 향상성을 유지하며, 체온유지와 생체 방어 기능을 한다. 사람의 혈액은 여러 가지 세포 혈구와 그 세포를 포함하는 맑은 액체인 혈장로 구성되어 있다. 혈구는 적혈구, 백혈구, 혈소판으로 구성되어 있다. 적혈구는 붉은 색을 띠는 세포로 산소를 몸의 조직으로 운반하는 역할을 한다. 혈소판은 혈액응고에 중요한 역할을 하는 세포이다. 백혈구는 인간의 면역에 관계하는 세포이며 구체적으로 다음과 같은 세포들이 있다. 1.과립구(granulocyte): 과립구란 백혈구의 60%를 차지하며, 세포속에 특이한 과립을 가지고 있는 세포이며, 다음과 같은 3가지의 세포가 이곳에 포함이 된다. -호염기구(basophil): 염기성염색약에 잘 염색되는 과립을 가지고 있다. 불규칙한 모양의 세포로 푸른 색을 띠는 과립이 너무 많이 있어서 핵이 잘 보이지 않는다. -호산구(eosinophil): 산성염색약에 잘 염색되는 과립을 가지고 있고, 대개 기생충의 감염이나, 알러지에서 많이 증가한다. 대개 2개의 핵을 가지고 있으며 핵사이에 가는 실같은 것으로 이어져 있다. -호중구(neutrophil): 산성염색약이나 염기성염색약에 의하여 모두 잘 염색되는 과립을 가지는 세포로 대개 3개의 핵을 가진다. 그리고 핵사이에 가는 실같은 구조물이 있어서 핵을 서로 이어주고 있다. 2.단핵구(monocyte): 다각형모양을 가진 세포로 과립을 가지고 있지 않다. 외계로부터 들어온 물질을 잡아먹는 역할과 그것에 대한 정보를 제공하는 역할을 하여 면역에 관계한다. 이것이 혈액 중에 존재하지 않고 조직에 고정되어 있는 경우에 이것을 큰포식세포라고 한다. 3.림프구(lymphocyte): 작은 원형의 세포로 면역에 중추적인 역할을 한다. |
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| 영문 | blood gas | 한글 | 혈액가스, 혈액기체 |
|---|---|---|---|
| 설명 | 혈액 속에 용해되어 있는 산소, 이산화탄소, 질소 따위의 기체. 혈액의 산성-염기성의 정도를 측정할 수 있다. |
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| 영문 | blood test | 한글 | 혈액검사 |
|---|---|---|---|
| 설명 | 혈액형이나 질병 유무 따위를 알기 위하여 피를 뽑아 행하는 검사. 몸 전체의 장기나 조직에 병터가 있으면 이들 성분에 변화가 있게 되어 진단에 큰 도움을 준다. |
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| 영문 | blood-brain barrier | 한글 | 혈액뇌장벽 |
|---|---|---|---|
| 설명 | 혈액으로부터 뇌로는 지질용해성이 높은 약물밖에 이행되지 않는다. 수용성의 약물을 뇌로 이행되지 않게 하고 있는 것이 혈액뇌장벽이며 뇌의 모세혈관 내피세포, 모세혈관 주위의 세포가 장벽이 되고 있다. 물질교환은 수동확산에 의해 이루어지지만, 뇌의 생리적 활동에 필요한 물질은 이온형이라도 담체를 통해 이행된다. |
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| 영문 | blood volume | 한글 | 혈액량 |
|---|---|---|---|
| 설명 | 체내에 존재하는 혈액의 총량으로서, 보통 리터 또는 체중 1kg에 대하여 리터수로 표시한다. |
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| RDHBF | regional distribution of hepatic blood flow |
|---|---|
| RMBF | regional myocardial blood flow |
| RMP | rapidly miscible pool; regional medical program; regional myocardial infarction; resting membrane po... |
| BF | bentonite flocculation; bile flow; black female; blastogenic factor; blister fluid; blood flow; body... |
| CF | calcaneal fibular [ligament]; calcium leucovorin; calf blood flow; calibration factor; cancer-free; ... |
| cytometry, flow | Analysis of biological material by detection of the light-absorbing or fluorescing properties of cells or subcellular fractions such as chromosomes passing in a narrow stream through a laser beam. Flow cytometry is used with automated sorting devices to sort successive droplets of the stream into different fractions depending on the fluorescence emitted by each droplet. (12 Dec 1998) |
|---|---|
| pulsatile flow | Rhythmic, intermittent propagation of a fluid through a vessel or piping system, in contrast to constant, smooth propagation, which produces laminar flow. The quality of blood flow, whether smooth (laminar) or pulsatile, is important to the integrity of the tissues being artificially perfused by various heart assist devices or in regional perfusion. (12 Dec 1998) |
| sheared flow | <radiobiology> Fluid flow where the magnitude of the fluid velocity changes along a direction perpedicular to the direction of the fluid flow. (Freeway traffic often exhibits sheared flow in that traffic in the fast lane moves more rapidly than traffic in the slow lane with the exits.) Sheared flow typically correlates with reduced transport and enhanced confinement. (This definition is rather informal and may not be fully technically correct - R.F. Heeter) (09 Oct 1997) |
| shear flow | A flow of a material in which parallel planes in the material are displaced in a direction parallel to each other. (05 Mar 2000) |
| shuttle flow | <cell biology> Bulk flow of the cytoplasm of cells. most conspicuous in large cells such as amoebae and the internodal cells of Chara where the rate of movement may be as high as 100 m/sec. See: cyclosis. (18 Nov 1997) |
| newtonian flow | The type of flow characteristic of a newtonian fluid. (05 Mar 2000) |
| Doppler colour flow | A computer-generated colour image produced by Doppler ultrasonography in which different directions of flow are represented by different hues. This technique is typically used to examine blood flow when evaluating heart disease. Where obstructions (for instance, arterial plaques) exist, blood flow will alter according to the principles of fluid mechanics. Eddies and reversals are readily apparent on the colour image. See: Doppler ultrasonography. (05 Mar 2000) |
| instream flow incremental methodology | Technique to predict the biomass of a fish species or life stage that a stream reach can support at a given flow, given knowledge of the fishes' physical habitat preferences. (09 Oct 1997) |
| isovolume pressure-flow curve | The relationship between transpulmonary pressure and respiratory air flow, expressed as a function of lung volume. (05 Mar 2000) |
| effective renal plasma flow | <physiology> The amount of plasma flowing to the parts of the kidney that have a function in the production of constituents of urine; the clearance of substances such as iodopyracet and p-aminohippuric acid, assuming that the extraction ratio in the peritubular capillaries is 100%. It is the amount of plasma perfusing the kidney tubules per unit time, generally measured by p-aminohippurate clearance. It should be differentiated from renal plasma flow which is approximately 10% greater than the effective renal plasma flow. (07 Mar 2000) |
| karyotyping, flow | Use of flow cytometry to analyze and/or separate chromosomes on the basis of their DNA content. Flow cytometry detects the light- absorbing or fluorescing properties of chromosomes passing in a narrow stream through a laser beam and with automated sorting devices can sort successive droplets of the stream into different fractions depending on the fluorescence emitted by each droplet. (12 Dec 1998) |
| flow | 1. To move with a continual change of place among the particles or parts, as a fluid; to change place or circulate, as a liquid; as, rivers flow from springs and lakes; tears flow from the eyes. 2. To become liquid; to melt. "The mountains flowed down at thy presence." (Is. Lxiv. 3) 3. To pproceed; to issue forth; as, wealth flows from industry and economy. "Those thousand decencies that daily flow From all her words and actions." (Milton) 4. To glide along smoothly, without harshness or asperties; as, a flowing period; flowing numbers; to sound smoothly to the ear; to be uttered easily. "Virgil is sweet and flowingin his hexameters." (Dryden) 5. To have or be in abundance; to abound; to full, so as to run or flow over; to be copious. "In that day . . . The hills shall flow with milk." (Joel III. 18) "The exhilaration of a night that needed not the influence of the flowing bowl." (Prof. Wilson) 6. To hang loose and waving; as, a flowing mantle; flowing locks. "The imperial purple flowing in his train." (A. Hamilton) 7. To rise, as the tide; opposed to ebb; as, the tide flows twice in twenty-four hours. "The river hath thrice flowed, no ebb between." (Shak) 8. To discharge blood in excess from the uterus. Origin: AS. Flowan; akin to D. Vloeijen, OHG. Flawen to wash, Icel. Floa to deluge, Gr. To float, sail, and prob. Ultimately to E. Float, fleet. 80. Cf. Flood. 1. A stream of water or other fluid; a current; as, a flow of water; a flow of blood. 2. A continuous movement of something abundant; as, a flow of words. 3. Any gentle, gradual movement or procedure of thought, diction, music, or the like, resembling the quiet, steady movement of a river; a stream. "The feast of reason and the flow of soul." (Pope) 4. The tidal setting in of the water from the ocean to the shore. See Ebb and flow, under Ebb. 5. A low-lying piece of watery land; called also flow moss and flow bog. Source: Websters Dictionary (01 Mar 1998) |
| flow cytoenzymology | A technique for for separating and sorting cells based on the presence ofspecific enzymes that create acoloured material when they bind to a substrate. (09 Oct 1997) |
| flow cytometry | <technique> Flow cytometry is an emerging technique which holds great promise for the separation, classification and quantitation of blood cells and antibodies which affect blood cells. Complex computerised instruments are used to pass a monocellular stream of cells, platelets or other microscopic particulate elements through a beam of laser light. The cells are categorised first by size and then computer analysed to sort the mixture of cellular elements into cell type by size. Cells are labelled with fluorescent dye and then passed, in suspending medium, through a narrow dropping nozzle so that each cell is in a small droplet. A laser based detector system is used to excite fluorescence and droplets with positively fluorescent cells are given an electric charge. Charged and uncharged droplets are separated as they fall between charged plates and so collect in different tubes. The machine can be used either as an analytical tool, counting the number of labelled cells in a population or to separate the cells for subsequent growth of the selected population. Further sophistication can be built into the system by using a second laser system at right angles to the first to look at a second fluorescent label or to gauge cell size on the basis of light scatter. The great strength of the system is that it looks at large numbers of individual cells and makes possible the separation of populations with, for example: particular surface properties. Tabulation of counted data in conjunction with size analysis enables determination of relative percentages of each specific cellular subset for which monoclonal antibody conjugates are utilised, even when the size of the cell is identical to other subset species. Flow cytometry is a slightly imprecise but common term for the use of the Fluorescence-activated Cell Sorter (FACS). (01 Dec 1998) |
| flow cytophotometry | <technique> Flow cytometry is an emerging technique which holds great promise for the separation, classification and quantitation of blood cells and antibodies which affect blood cells. Complex computerised instruments are used to pass a monocellular stream of cells, platelets or other microscopic particulate elements through a beam of laser light. The cells are categorised first by size and then computer analysed to sort the mixture of cellular elements into cell type by size. Cells are labelled with fluorescent dye and then passed, in suspending medium, through a narrow dropping nozzle so that each cell is in a small droplet. A laser based detector system is used to excite fluorescence and droplets with positively fluorescent cells are given an electric charge. Charged and uncharged droplets are separated as they fall between charged plates and so collect in different tubes. The machine can be used either as an analytical tool, counting the number of labelled cells in a population or to separate the cells for subsequent growth of the selected population. Further sophistication can be built into the system by using a second laser system at right angles to the first to look at a second fluorescent label or to gauge cell size on the basis of light scatter. The great strength of the system is that it looks at large numbers of individual cells and makes possible the separation of populations with, for example: particular surface properties. Tabulation of counted data in conjunction with size analysis enables determination of relative percentages of each specific cellular subset for which monoclonal antibody conjugates are utilised, even when the size of the cell is identical to other subset species. Flow cytometry is a slightly imprecise but common term for the use of the Fluorescence-activated Cell Sorter (FACS). (01 Dec 1998) |