| 영문 | optic nerve | 한글 | 시각신경 |
|---|---|---|---|
| 설명 | 시각을 인지하는 신경. 이 신경은 단지 감각신경으로서만 작용한다. 따라서 어떤 사물을 따라 눈을 움직일 수 있는 것은 이 시각신경과는 무관하다(이것은 눈돌림신경(oculomotor nerve)에 의해 가능하다). 또한 시각신경은 고위중추신경계인 뇌에서 직접 분지하므로 손상시 재생은 불가능하며, 이에 대한 치료법은 없다. |
||
| 영문 | nerve | 한글 | 신경 |
|---|---|---|---|
| 설명 | 생물이 자신의 몸과 주위에서 일어나는 각종 변화를 감지하고 종합하여 적절한 반응을 일으키도록 하는 기관. 수많은 신경 세포로 되어 있다. 육안상 끈 모양의 구조로서, 중추신경계와 신체의 각 부분 사이에서 신경충동을 전달하는 신경섬유의 집합이다. 신경은 신경섬유의 다발을 둘러싸는 결합조직성의 집(sheath)으로 이루어진다. 각 신경섬유속은 신경다발막(perineurium)이라 부르는 결합조직성의 고유의 집으로 둘러싸여 있으며, 막의 내면은 편평한 중피세포의 막으로 되어 있다. 매우 작은 신경은 모신경에서 나온 단 한개의 신경삭으로 이루어지기도 한다. 이러한 신경속내에서, 현미경으로 관찰될 수 있는 각 신경섬유는 간질성 결합조직인 신경섬유막(endoneurium)으로 둘러싸여 있다. 각 신경섬유(축삭과 이를 싸고 있는 집)는 원형질로 된 기질인 축삭형질(axoplasm)과 이것내의 유형성분으로 구성되어 있고, 전체구조는 얇은 축삭집(axolemma)으로 둘러싸여 있으며, 신경집세포에 유래한 지질층인 말이집(myelin sheath)이 있는 것도 있고, 없는 것도 있다.  |
||
| 영문 | nerve | 한글 | 신경 |
|---|---|---|---|
| 설명 | 여러 기관들의 서로간 상호연결체계가 바로 신경계이다. 이러한 신경계는 각 신경세포들에 의해 이루어지고 있으며, 여기에는 중추신경계(central nerve system: CNS)와 말초신경계(peripheral nerve system: PNS)가 있다. 중추신경계란 뇌와 척수를 말하며, 말초신경계는 12쌍의 뇌신경(cranial nerve: 뇌에서 기시하여 주로 얼굴부위와 목 부위에 분포한다)과 31쌍의 척수신경(spinal nerve: spinal cord에서 각기 양쪽으로 쌍을 이루어 나오는데 주로 목이하부위의 신체 각 부분으로 분포하게 된다)으로 구성되어 있다. 또한 말초신경계에는 앞에서 말한 뇌신경과 척수신경외에 자율신경계가 존재한다. 자율신경계는 다시 교감신경과 부교감신경으로 나뉘어져 서로간의 올바른 상호작용으로 몸속에서 여러 가지 작용을 수행한다. |
||
| 영문 | nerve cell | 한글 | 신경세포 |
|---|---|---|---|
| 설명 | 신경세포는 올바른 신경전달을 위한 각 부분별로 나뉘어져 있다. 신경세포에서는 전해져오는 자극을 전기적인 신호로 바뀌어 보내거나 받게 된다. 이런 전기적인 현상은 각 신경세포내에 존재하는 각 이온채널(ion channel: ion이란 나트륨, 칼륨 등을 지칭하는 말들로써, 이들이 세포막에 의해 나뉘어질 때 생기는 전압차가 전기적 자극을 일으키고 유지하는데 결정적인 역할을 한다)들의 작용에 의해 이루어지게 된다. |
||
| 영문 | facial nerve | 한글 | 얼굴신경 |
|---|---|---|---|
| 설명 | 표정근을 지배하는 큰 운동신경과 작은 중간신경으로 구성된다. 좁은 의미의 얼굴신경과 중간신경으로 이루어지는 혼합신경이다. 속귀신경과 함께 속귓길로 들어가고 그 바닥에서 속귀신경과 갈라져 얼굴신경관으로 들어가, 거의 직각으로 구부러지는 부분을 얼굴신경무릎이라 하며, 여기에 무릎신경마디가 있다. |
||
| TF | free thyroxine; tactile fremitus; tail flick [reflex]; temperature factor; testicular feminization; ... |
|---|---|
| HCG, hCG | Human Chorionic Gonadotropin; 사람융모성성선자극호르몬 1. Placental Glycoprotein Hormone &nbs... |
| NG | nasogastric; neoplastic growth; new growth; nitroglycerin; nodose ganglion; no growth; not given |
| NGF | nerve growth factor |
| NGFA | nerve growth factor alpha |
| insulin-like-growth-factor-binding protein 6 | One of the six homologous soluble proteins that bind insulin-like growth factors (somatomedins) and modulate their mitogenic and metabolic actions at the cellular level. (12 Dec 1998) |
|---|---|
| insulin-like growth-factor-binding proteins | A family of soluble proteins that bind insulin-like growth factors and modulate their biological actions at the cellular level. (int j gynaecol obstet 1992;39(1):3-9) (12 Dec 1998) |
| insulin-like growth factor I | <chemical> A well-characterised basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on somatotropin. It is believed to be mainly active in adults in contrast to insulin-like growth factor II, which is a major foetal growth factor. Chemical name: Insulin-like growth factor I (12 Dec 1998) |
| insulin-like growth factor II | <chemical> A well-characterised neutral peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like and mitogenic activities. The growth factor has a major, but not absolute, dependence on somatotropin. It is believed to be a major foetal growth factor in contrast to insulin-like growth factor I, which is a major growth factor in adults. Chemical name: Insulin-like growth factor II (12 Dec 1998) |
| T-cell growth factor | <cytokine> A hormone-like substance released by stimulated T lymphocytes, causes activation and differentiation of other T lymphocytes independently of antigen. A type of interleukin, a chemical messenger, a substance that can improve the body's response to disease. It stimulates the growth of certain disease-fighting blood cells in the immune system. It is secreted by Thl CD4 cells to stimulate CD8 cytotoxic T-1yrnphocytes. Interleukin 2 also increases the proliferation and maturation of the CD4 cells themselves. During HIV infection, Interleukin-2 production gradually declines. Use of interleukin 2 therapy is under study as a way to raise CD4 cell counts and restore immune function. Acronym: IL-2 (12 Dec 1998) |
| T-cell growth factor-1 | <cytokine> A hormone-like substance released by stimulated T lymphocytes, causes activation and differentiation of other T lymphocytes independently of antigen. A type of interleukin, a chemical messenger, a substance that can improve the body's response to disease. It stimulates the growth of certain disease-fighting blood cells in the immune system. It is secreted by Thl CD4 cells to stimulate CD8 cytotoxic T-1yrnphocytes. Interleukin 2 also increases the proliferation and maturation of the CD4 cells themselves. During HIV infection, Interleukin-2 production gradually declines. Use of interleukin 2 therapy is under study as a way to raise CD4 cell counts and restore immune function. Acronym: IL-2 (12 Dec 1998) |
| T-cell growth factor-2 | <cytokine> A soluble cytokine factor produced by activated T-lymphocytes that promotes antibody production by causing proliferation and differentiation of B-cells. Interleukin-4 induces the expression of class II major histocompatibility complex and fc receptors on B-cells. It also acts on T-lymphocytes, mast cell lines, and several other haematopoietic lineage cells including granulocyte, megakaryocyte, and erythroid precursors, as well as macrophages. Acronym: IL-4 (12 Dec 1998) |
| transforming growth factor | <growth factor> Proteins secreted by transformed cells that can stimulate growth of normal cells. Unfortunate misnomer, since they induce aspects of transformed phenotype, such as growth in semi solid agar, but do not actually transform. Transforming growth factor alpha, 50 amino acid polypeptide originally isolated from viral transformed rodent cells, contains EGF like domain and binds to EGF receptor. Stimulates growth of microvascular endothelial cells, i.e. Is angiogenic. Transforming growth factor beta a homodimer of two 112 chains, polypeptide is secreted by many different cell types, stimulates wound healing but in vitro is also a growth inhibitor for certain cell types. The transforming growth factor family includes many of the bone morphogenetic proteins. Acronym: TGF (18 Nov 1997) |
| transforming growth factor alpha | Factor isolated in a variety of tissues including epithelium, and maternal decidua. It is closely related to epidermal growth factor (epidermal growth factor-urogasterone) and binds to the egf receptor. Tgf-alpha acts synergistically with tgf-beta in inducing phenotypic transformation, but its physiological role is unknown. (12 Dec 1998) |
| transforming growth factor beta | Factor synthesised in a wide variety of tissues including platelets, placenta, and both normal and transformed cell lines. It acts synergistically with tgf-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. Tgf-beta also has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. There are at least three forms of tgf-beta: tgf-beta1, tgf-beta2, and tgf-beta1.2. The latter is a heterodimer made up of both tgf-beta1 and tgf-beta2. (12 Dec 1998) |
| endothelium-derived growth factor synthase | <enzyme> Converts l-arginine to a smooth muscle relaxing factor and stimulates the formation of cyclic-GMP Registry number: EC 1.5.1.- Synonym: edrf synthase (26 Jun 1999) |
| epidermal growth factor | <growth factor> A mitogenic polypeptide initially isolated from male mouse submaxillary gland. The name refers to the early bioassay, but epidermal growth factor is active on a variety of cell types, especially but not exclusively epithelial. Human equivalent originally named urogastrone owing to its hormone activity. Acronym: EGF (18 Nov 1997) |
| epidermal growth factor-urogastrone | <chemical> Single chain, nonhelical, acidic polypeptides of about 52 amino acids found in most mammals. Epidermal growth factor and urogastrone are not identical but seem to share biological acivities. They promote growth of, and cell proliferation in, certain tissues, especially epidermal structures and inhibit acid secretion by the stomach. They have been used to treat gastrointestinal ulcers. Chemical name: Epidermal growth factor (12 Dec 1998) |
| keratinocyte growth factor | <growth factor> A growth factor structurally related to fibroblast growth factor. (18 Nov 1997) |
| fibroblast growth factor | <growth factor> Acidic fibroblast growth factor (alpha FGF, HBGF 1) and basic FGF (beta FGF, HBGF 2) are the two founder members of a family of structurally related growth factors for mesodermal or neuroectodermal cells. Synonym: heparin binding growth factor. Acronym: FGF (18 Nov 1997) |