| prostatic intraepithelial neoplasia | A premalignant change arising in the prostatic epithelium, regarded as the most important and most likely precursor of prostatic adenocarcinoma. The neoplasia takes the form of an intra-acinar or ductal proliferation of secretory cells with unequivocal nuclear anaplasia, which corresponds to nuclear grade 2 and 3 invasive prostate cancer. (12 Dec 1998) |
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| prostatic massage | Manual expression of prostatic secretions by digital rectal technique, the emptying of prostatic sini and ducts by repeated downward compression manoeuvres, used in the treatment of various congestive and inflammatory prostatic conditions. (05 Mar 2000) |
| prostatic plexus | An autonomic plexus of nerves intimately associated with the capsule of the prostate, derived from the inferior hypogastric plexus, and giving rise to the cavernous nerves to the erectile tissue of the penis; surgical injury of this plexus ofter results in impotency. Synonym: plexus prostaticus. (05 Mar 2000) |
| prostatic sheath | Loose fibrous, partly vascular enclosure of the prostate and its dense (true) fibrous capsule; it is continuous inferiorly with the superior fascia of the urogenital diaphragm and posteriorly becomes part of the rectovesical septum; it contains the prostatic venous plexus. (05 Mar 2000) |
| prostatic sinus | The groove on either side of the urethral crest in the prostatic part of the urethra into which the prostatic ducts open. Synonym: sinus prostaticus. (05 Mar 2000) |
| prostatic urethra | The prostatic part of the male urethra, about 2.5 cm in length, that traverses the prostate; it includes the seminal colliculus, and the ejaculatory and prostatic ducts open into it. Synonym: pars prostatica urethrae. (05 Mar 2000) |
| prostatic utricle | A minute pouch in the prostate opening on the summit of the seminal colliculus, the analogue of the uterus and vagina in the female, being the remains of the fused caudal ends of the paramesonephric ducts. Synonym: utriculus prostaticus, masculine uterus, Morgagni's sinus, sinus pocularis, uterus masculinus, vagina masculina, vesica prostatica, Weber's organ. (05 Mar 2000) |
| prostatic venous plexus | A venous plexus, arising chiefly from the dorsal vein of the penis, situated below the base of the bladder at the sides of the prostate. See: prostaticovesical plexus. Synonym: plexus venosus prostaticus, plexus pudendalis, Santorini's labyrinth. (05 Mar 2000) |
| Young prostatic tractor | A short, straight tubular instrument with blades at its tip, which can be rotated open and closed; it is passed into the prostatic urethra, through a prostatotomy incision made during the later stages of open perineal prostatectomy, with its tip into the bladder; direct traction on the instrument brings the prostate gland down into the operative field where enucleation can be more easily performed. (05 Mar 2000) |
| adenovirus e1a proteins | Proteins transcribed from the e1a region of adenovirus which are involved in positive regulation of transcription of the early genes. (12 Dec 1998) |
| adenovirus e1b proteins | Proteins transcribed from the e1b region of adenovirus which are involved in regulation of the levels of early and late gene expression. (12 Dec 1998) |
| adenovirus e1 proteins | The very first viral gene products synthesised after cells are infected with adenovirus. The e1 region of the genome has been divided into two major transcriptional units, e1a and e1b, each expressing proteins of the same name (adenovirus e1a proteins and adenovirus e1b proteins). (12 Dec 1998) |
| adenovirus e2 proteins | Proteins transcribed from the e2 region of adenovirus. Several of these are required for viral DNA replication. (12 Dec 1998) |
| adenovirus e3 proteins | Proteins transcribed from the e3 region of adenovirus but not essential for viral replication. The e3 19k protein mediates adenovirus persistence by reducing the expression of class I major histocompatibility complex antigens on the surface of infected cells. (12 Dec 1998) |
| adenovirus e4 proteins | Proteins transcribed from the e4 region of adenovirus. The e4 19k protein transactivates transcription of the adenovirus e2f protein and complexes with it. (12 Dec 1998) |