| Nagele's rule | Means of estimating date of delivery by counting back three months from the first day of the last menstrual period and adding seven days. (05 Mar 2000) |
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| New Hampshire rule | Pioneering American test of criminal responsibility (1871): "if the [criminal] act was the offspring of insanity, a criminal intent did not produce it." (05 Mar 2000) |
| Durham rule | An American test of criminal responsibility (1954): "an accused is not criminally responsible if his unlawful act was the product of mental disease or mental defect." (05 Mar 2000) |
| isoprene rule | The classical, outmoded statement that naturally occurring terpenes are built up by condensation of isoprene units by either a 1-4 linkage ("head to tail") or a 4-4 linkage ("tail to tail"). (05 Mar 2000) |
| Ogino-Knaus rule | The time in the menstrual period when conception is most likely to occur is at about midway between two menstrual periods; fertilization of the ovum is least likely just before or just after menstruation; the basis for the rhythm method of contraception. (05 Mar 2000) |
| Trusler's rule for pulmonary artery banding | A method that gives guidance as to the correct tightness of the band; the degree of banding for a complex congenital cardiac anomaly with bidirectional shunting less than that for simple ones. (05 Mar 2000) |
| Jackson's rule | After an epileptic attack, simple and quasiautomatic functions are less affected and more rapidly recovered than the more complex ones. (05 Mar 2000) |
| Jordan's rule | <genetics> An evolutionary rule that states that the closest genetic relatives of a given species are found very near it, but the two groups are isolated by some kind of natural barrier (such as a river) that neither species can cross easily. (09 Oct 1997) |
| Young's rule | An obsolete rule to determine a child's dose: 12 is added to the child's age and the sum is divided by the age; the adult dose divided by the figure so obtained gives the proper dose. (05 Mar 2000) |
| Le Bel-van't Hoff rule | The number of stereoisomers of an organic compound is 2n where n represents the number of asymmetric carbon atoms (unless there is an internal plane of symmetry). A corollary of their simultaneously announced conclusions, in 1874, that the most probable orientation of the bonds of a carbon atom linked to four groups or atoms is toward the apexes of a tetrahedron, and that this accounted for all then-known phenomena of molecular asymmetry (which involved a carbon atom bearing four different atoms or groups). See: stereoisomerism. (05 Mar 2000) |
| Liebermeister's rule | In adult febrile tachycardia, about eight pulse beats correspond to an increase of 1°C. (05 Mar 2000) |
| Aaron's sign | <clinical sign> In acute appendicitis, a referred pain or feeling of distress in the epigastrium or precordial region on continuous firm pressure over McBurney's point. (05 Mar 2000) |
| Abadie's sign of tabes dorsalis | Insensibility to pressure over the tendo achillis. (05 Mar 2000) |
| Abrahams' sign | <clinical sign> An obsolete sign: Rales and other adventitious sounds, changes in the respiratory murmurs, and increase in the whispered sound can be heard on auscultation over the acromial end of the clavicle some time before they become audible at the apex; heard primarily in pulmonary tuberculosis affecting the apical portion of the lung, a dull-flat note, i.e., one between the normal dullness at the right apex and absolute flatness, heard on percussion in that region, indicating progress from incipient to advanced tuberculosis. (05 Mar 2000) |
| accessory sign | <clinical sign> A finding frequently but not consistently present in a disease. Synonym: assident sign. (05 Mar 2000) |
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