| PIR | minute parasite of red blood cells of mammals transmitted by a tick and causing diseases of domestic animals |
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| PIR | (Russian) small fruit or meat turnover baked or fried |
| PIR | a rapid spin of the body (especially on the toes as in ballet) |
| PIR | do a pirouette, usually as part of a dance |
| PIR | a nonsteroidal anti-inflammatory drug (trade name Feldene) used to treat arthritis and other inflammatory conditions |
| PIR | (Russian) small fruit or meat turnover baked or fried |