| pepsin a | <enzyme> Formed from pig pepsinogen by cleavage of one peptide bond. The enzyme is a single polypeptide chain and is inhibited by methyl 2-diaazoacetamidohexanoate. It cleaves peptides preferentially at the carbonyl linkages of phenylalanine or leucine and acts as the principal digestive enzyme of gastric juice. Pharmacological action: gastrointestinal agents. Registry number: EC 3.4.23.1 (12 Dec 1998) |
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| pepsinate | To mix pepsin with. (05 Mar 2000) |
| pepsinhydrochloric | <physiology> Same as Peptohydrochloric. Source: Websters Dictionary (01 Mar 1998) |
| pepsiniferous | Producing pepsin. Synonym: pepsiniferous. (05 Mar 2000) |
| pepsinogen | The inactive precursor (42.5 kD) of pepsin. (18 Nov 1997) |
| pepsinogenous | Producing pepsin. Synonym: pepsiniferous. (05 Mar 2000) |
| pepsinuria | Excretion of pepsin in the urine. Origin: pepsin + G. Ouron, urine (05 Mar 2000) |
| pepstatin | An inhibitor peptide from actinomycetes that inhibits pepsin and cathepsin D. (05 Mar 2000) |
| pepstatins | <chemical> N-acylated oligopeptides isolated from culture filtrates of actinomycetes, which act specifically to inhibit acid proteases such as pepsin and renin. Pharmacological action: protease inhibitors. (12 Dec 1998) |
| peptic | Pertaining to pepsin or to digestion, related to the action of gastric juices. Origin: Gr. Peptikos (18 Nov 1997) |
| peptic cell | <pathology> Cells of the basal part of the gastric glands of the stomach. They contain extensive rough endoplasmic reticulum and zymogen granules and secrete pepsinogen, the inactive precursor of pepsin and rennin. (18 Nov 1997) |
| peptic digestion | That part of digestion, chiefly of the proteins, carried on in the stomach by the enzymes of the gastric juice. Synonym: peptic digestion. (05 Mar 2000) |
| peptic gland | A pepsin-secreting gland. See: gastric glands. (05 Mar 2000) |
| peptic ulcer | <gastroenterology> An ulcer in the wall of the stomach or duodenum resulting from the digestive action of the gastric juice on the mucous membrane when the latter is rendered susceptible to its action. (13 Nov 1997) |
| peptic ulcer perforation | Penetration of a peptic ulcer through the stomach wall. May be free, i.e., at a point where the stomach wall faces a real or potential space,, or confined, i.e., at a point where the stomach wall is defended by contiguous or adjacent structures, such as the pancreas. (12 Dec 1998) |