| orotidine 5'-monophosphate | Orotidine 5'-monophosphate;an intermediate in the biosynthesis of the pyrimidine nucleosides (cytidine and uridine) that are found in nucleic acids. Synonym: orotidine 5'-monophosphate. (05 Mar 2000) |
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| orotidine-5'-phosphate decarboxylase | <enzyme> Orotidine-5'-phosphate carboxy-lyase. Catalyses the decarboxylation of orotidylic acid to yield uridylic acid in the final step of the pyrimidine nucleotide biosynthesis pathway. Chemical name: Orotidine-5'-phosphate carboxy-lyase Registry number: EC 4.1.1.23 (12 Dec 1998) |
| orotidinuria | Elevated levels of orotidine in the urine; has been observed in defects in and inhibition of orotidylic acid decarboxylase. (05 Mar 2000) |
| orotidylate | A salt or ester of orotidylic acid. (05 Mar 2000) |
| orotidylic acid | Orotidine 5'-monophosphate;an intermediate in the biosynthesis of the pyrimidine nucleosides (cytidine and uridine) that are found in nucleic acids. Synonym: orotidine 5'-monophosphate. (05 Mar 2000) |
| orotidylic acid decarboxylase | <enzyme> An enzyme that catalyses the conversion of OMP to UMP and CO2; a defect or inhibition of this enzyme will result in orotic aciduria and orotidinuria; this enzyme is a part of pyrimidine biosynthesis. Compare: uridylic acid synthase. Synonym: OMP decarboxylase. (05 Mar 2000) |
| orotidylic acid phosphorylase | <enzyme> The enzyme catalyzing the formation of orotidine-5'-phosphoric acid (orotidylic acid) from orotic acid and 5-phosphoribosyl-1-pyrophosphate in the course of pyrimidine nucleotide biosynthesis. Chemical name: Orotidine-5'-phosphate:pyrophosphate phospho-alpha-D-ribosyltransferase Registry number: EC 2.4.2.10 (12 Dec 1998) |
| orotidylic acid pyrophosphorylase | <enzyme> The enzyme catalyzing the formation of orotidine-5'-phosphoric acid (orotidylic acid) from orotic acid and 5-phosphoribosyl-1-pyrophosphate in the course of pyrimidine nucleotide biosynthesis. Chemical name: Orotidine-5'-phosphate:pyrophosphate phospho-alpha-D-ribosyltransferase Registry number: EC 2.4.2.10 (12 Dec 1998) |
| orotracheal intubation | Tracheal intubation through the mouth. (05 Mar 2000) |
| orotracheal tube | A tracheal tube inserted through the mouth. (05 Mar 2000) |
| Oroya fever | A generalised, acute, febrile, endemic, and systemic form of bartonellosis; marked by high fever, rheumatic pains, progressive, severe anaemia, and albuminuria. Synonym: Carrion's disease. (05 Mar 2000) |