| oncogene |
A gene that normally directs cell growth. If altered, an oncogene can promote or allow the uncontrolled growth of cancer. Alterations can be inherited or caused by an environmental exposure to carcinogens.
Ãâó: www.stjude.org/glossary
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| oncolysate |
An extract made from cancer cells that are infected with a lytic strain of virus. The extract contains both cancer cell proteins and virus proteins. Oncolysates are being studied as cancer vaccines.
Ãâó: www.stjude.org/glossary
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| oncolysis |
The breakdown, or lysis, of a tumor. This can occur by mechanical means, chemicals, or infectious agents such as viruses. Oncolytic viruses do not lyse most normal cells.
Ãâó: www.stjude.org/glossary
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| oncolytic |
Refers to viruses that kill cancer cells more often than they kill normal cells.
Ãâó: www.stjude.org/glossary
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| oncogene |
A gene that causes cells to grow in an uncontrolled manner, ie, that causes cancer. Oncogenes are mutant forms of normal functional genes (called proto-oncogenes) that have a role in normal cell proliferation. Oncogenes are found in tumours and in retroviruses; in the latter case, having been picked up along with retroviral genes during retroviral replication in the host. ...
Ãâó: www.fao.org/docrep/003/X3910E/X3910E18.htm
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