| PABP | pulmonary artery balloon pump |
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| PBP | penicillin-binding protein; porphyrin biosynthesis pathway; prostate-binding protein; pseudobulbar p... |
| PUMP | putative metalloproteinase |
| VPP | vacuolar proton pump; viral porcine pneumonia |
| NPH | 1) Neutral Protamine Hagedorn Insulin = Isophane Insulin Susp... |
| intra-aortic balloon pump | <cardiology, equipment> A device which is threaded into the aorta that augments the strength of the hearts contraction. The counter pulsation, produced by the inflation of a balloon within the aorta, provides an rhythmic increase in aortic pressures. The net effect is an increase in coronary artery blood flow. Intra-aortic balloon pump is a temporary lifesaving measure that is used to treat severe cardiac damage due to a massive heart attack. (27 Sep 1997) |
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| ion pump | A membranal complex of proteins that is capable of transporting ions against a concentration gradient using the energy from ATP. (05 Mar 2000) |
| electrogenic pump | <physiology> Ion pump that generates net charge flow as a result of its activity. The sodium potassium exchange pump transports two potassium ions inward across the cell membrane for each three sodiums transported outward. This produces a net outward current that contributes to the internal negativity of the cell. (05 Jan 1998) |
| jet ejector pump | A suction pump in which fluid under high pressure is forced through a nozzle into an abruptly larger tube where a high velocity jet, at a low pressure in accordance with Bernoulli's law, entrains gas or liquid from a side tube opening just beyond the end of the nozzle to create suction; e.g., the pump by which steam is used to evacuate an autoclave, a water aspirator. (05 Mar 2000) |
| force pump | <machinery> A pump having a solid piston, or plunger, for drawing and forcing a liquid, as water, through the valves; in distinction from a pump having a bucket, or valved piston. A pump adapted for delivering water at a considerable height above the pump, or under a considerable pressure; in distinction from one which lifts the water only to the top of the pump or delivers it through a spout. Source: Websters Dictionary (01 Mar 1998) |
| amorphous insulin zinc suspension | Sterile suspension of insulin in buffered water for injection, modified by the addition of zinc chloride such that the solid phase of the suspension is amorphous; it contains 40 or 80 units per ml; the duration of action is equivalent to that of insulin injection. Synonym: amorphous insulin zinc suspension, semilente insulin. (05 Mar 2000) |
| anti-insulin | A factor, usually an antibody, which antagonises the action of insulin. (05 Mar 2000) |
| anti-insulin antibody | A serologic blood test that is used to detect antibodies to insulin. This test is performed in insulin dependent diabetics who exhibit insulin resistance. The presence of antibodies denotes a positive result. (27 Sep 1997) |
| biphasic insulin | <protein> A type of insulin that is a mixture of intermediate- and fast-acting insulin. (09 Oct 1997) |
| receptors, insulin | Cell surface proteins that bind insulin and trigger intracellular changes which influence the behaviour of cells. The best understood physiological consequence of insulin receptor activation is increased transport of glucose into most cells, which controls the rate of carbohydrate metabolism. The insulin receptor is a multifunctional protein complex that has intrinsic tyrosine kinase activity and is capable of autophosphorylation. (12 Dec 1998) |
| receptors, insulin-like-growth factor I | Specific proteins on or in cells to which insulin-like growth factor I (somatomedin c) binds and thereby modifies the function of the cells. These receptors contain transmembrane and cytosolic domains, bind igf-I preferentially, and have high-affinity sites for igf-II. The alpha-subunit has a mw of 130 kD and the beta subunit possesses tyrosine kinase activity. (12 Dec 1998) |
| receptors, insulin-like-growth-factor II | Specific proteins on or in cells to which insulin-like growth factor II and mannose-6-phosphate bind and thereby modify the function of the cells. These receptors have a mw of 250 kD and possess no tyrosine kinase activity. (12 Dec 1998) |
| regular insulin | A rapidly acting form of insulin which is a clear solution and may be administered intravenously as well as subcutaneously; may be mixed with longer acting forms of insulin to extend the duration of effect. Onset of effect occurs in 1/2 to 1 hour, peak effects are observed in 2 to 3 hours, and the duration of effect is about 5 to 7 hours. Synonym: globin insulin. (05 Mar 2000) |
| regular insulin injection | A preparation that may contain 20, 40, 80, 100, or 500 USP insulin units per ml, although the trend is toward standardizing all insulin preparations at 100 units per ml; it is administered subcutaneously, occasionally intravenously, and has a rapid onset of action, has a brief duration (5 to 7 hours), and is compatible for mixing with long-acting insulin preparations; used in the treatment of diabetic acidosis and insulin coma. Synonym: regular insulin injection. (05 Mar 2000) |
| globin insulin | A rapidly acting form of insulin which is a clear solution and may be administered intravenously as well as subcutaneously; may be mixed with longer acting forms of insulin to extend the duration of effect. Onset of effect occurs in 1/2 to 1 hour, peak effects are observed in 2 to 3 hours, and the duration of effect is about 5 to 7 hours. Synonym: globin insulin. (05 Mar 2000) |
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