| GM | gastric mucosa; Geiger-Muller [counter]; general medicine; genetic manipulation; geometric mean; gia... |
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| GP | gangliocytic paraganglioma; gastroplasty; general paralysis, general paresis; general practice, gene... |
| HGMCR | human genetic mutant cell repository |
| IGA | infantile genetic agranulocytosis |
| VG | genetic variance |
| endocardial cushion defect | <radiology> Persistence of primitive atrioventricular canal and anomalies of AV valves associated with: Down syndrome: in 25% of Trisomy 21 an ECD is present; in 45% of ECD Trisomy 21 is present, asplenia/polysplenia types: complete (AV canal), partial findings: gooseneck deformity on angiogram, increased pulmonary vascularity, enlarged pulmonary artery, enlarged RV, LV, RA; normal LA (secondary to atrial septal defect) (12 Dec 1998) |
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| enzyme defect | A disorder resulting from a deficiency (or functional abnormality) of an enzyme. In 1902 Archibald Garrod first attributed a disease to an enzyme defect: an inborn error of metabolism. Today, newborns are routinely screened for certain enzyme defects such as PKU (phenylketonuria) and galactosaemia, an error in the handling (metabolism) of the sugar galactose. (12 Dec 1998) |
| fibrous cortical defect | A common 1 to 3 cm defect in the cortex of a bone, most commonly the lower femoral shaft of a child, filled with fibrous tissue. Nonosteogenic or nonossifying fibroma by convention refers to lesions greater than 3 cm in diameter. See: nonossifying fibroma. Synonym: nonosteogenic fibroma. (05 Mar 2000) |
| uterine filling defect | <radiology> Technical, bubble, blood clot, mucoid material, congenital fold, pseudoadhesions / ridging -- folds long axis, neoplasm, submucosal leiomyoma, adenoma, endometrial carcinoma, pregnancy-related, pregnancy, molar pregnancy, retained conceptus, polyp, septated uterus, synechiae, IUD, iatrogenic (post-op) (12 Dec 1998) |
| filling defect | Displacement of contrast medium by a space-occupying lesion in a radiographic study of a contrast-filled hollow viscus, such as a polyp on a barium enema; also applied to defects in the otherwise uniform distribution of radionuclide in an organ, such as a metastasis in the liver on a 99mTc-sulfur colloid scan. (05 Mar 2000) |
| filling defect in renal collecting system | <radiology> Common causes: transitional cell carcinoma, blood clot, lucent calculus (urate) less common causes: fungus ball, sloughed papilla, fibroepithelial polyp, invasion by hypernephroma, malakoplakia, vessel impression, metastases (12 Dec 1998) |
| lambdoid suture defect | <radiology> Well-defined lucent lesion, classically unilateral, associated with neurofibromatosis (12 Dec 1998) |
| luteal phase defect | Inadequate function of the corpus luteum that may prevent a fertilized egg from implanting in the uterus or may lead to early pregnancy loss. (09 Oct 1997) |
| active transport | <biochemistry, chemistry> Transport of ions, nutrients or other molecules into a cell against a concentration gradient, this requires the expenditure of energy through ATP hydrolysis. (06 May 1997) |
| anterograde transport | Movement of material from the cell body of a neuron into axons and dendrites retrograde axoplasmic transport also occurs). (18 Nov 1997) |
| atrial transport function | The role of the atria in filling and stretching the ventricles by their presystolic contraction, without which the force of ventricular contraction and hence the cardiac output may significantly decrease. (05 Mar 2000) |
| axonal transport | Directed transport of organelles and molecules along a nerve cell axon. Transport can be anterograde (from the cell body) or retrograde (toward the cell body). (alberts et al., molecular biology of the cell, 3d ed, pg3) (12 Dec 1998) |
| axoplasmic transport | Transport by way of flow of axoplasm toward cell soma (retrograde) or toward axon terminal (anterograde). (05 Mar 2000) |
| biological transport | The movement of materials (including biochemical substances and drugs) across cell membranes and epithelial layers, usually by passive diffusion. (12 Dec 1998) |
| biological transport, active | The movement of materials across cell membranes and epithelial layers against an electrochemical gradient, requiring the expenditure of metabolic energy. (12 Dec 1998) |