| fractures, stress | Fractures due to the strain caused by repetitive exercise. They are thought to arise from a combination of muscle fatigue and bone failure, and occur in situations where bone remodeling predominates over repair. The classical stress fracture is the march fracture of military personnel, in which the metatarsal undergoes repeated stress during marching. The most common sites of stress fractures are the metatarsus, fibula, tibia, and femoral neck. (12 Dec 1998) |
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| fractures, ununited | A fracture in which union fails to occur, the ends of the bone becoming rounded and eburnated, and a false joint occurs. (12 Dec 1998) |
| Fraenkel's pneumococcus | A gram-positive organism found in the upper respiratory tract, inflammatory exudates, and various body fluids of normal and/or diseased humans and, rarely, domestic animals. (12 Dec 1998) |
| Fraenkel, Albert | <person> German physician, 1848-1916. See: Fraenkel's pneumococcus, Fraenkel-Weichselbaum pneumococcus. (05 Mar 2000) |
| Fraenkel-Weichselbaum pneumococcus | A gram-positive organism found in the upper respiratory tract, inflammatory exudates, and various body fluids of normal and/or diseased humans and, rarely, domestic animals. (12 Dec 1998) |
| fraenulum | Origin: NL, dim. Of L. Fraenum a bridle. <anatomy> A fraenum. Source: Websters Dictionary (01 Mar 1998) |
| fragile site | Places on chromosomes that tend to break more often than other places. These places also tend to be where chromosomal translocations (a type of chromosomal mutation) occur. (09 Oct 1997) |
| fragile x chromosome | X chromosome with a fragile site associated with a frequent form of mental retardation. The fragile X chromosome was first sighted by Herbert A. Lubs in 1969. The fragile X is also called FRAXA (the second A signifies it was the first FRAgile site found on the X chromosome). It is due a trinucleotide repeat (a recurring motif of 3 bases) in the DNA at that spot. (12 Dec 1998) |
| fragile X syndrome | <syndrome> most frequent cause of mental retardation. There is an expanded trinucleotide repeat CGG in the fra(X) gene. There is usually a constricted section on the long arm of the X chromosome. After puberty these patients often exhibit large prominent ears, long narrow face, coarse facial features and macroorchidism. Mental retardation in males is characteristic although the manifestations of the syndrome are highly variable. A preponderance of males are affected but it also affects 30% of carrier females and about 20% of obligate carrier males are not affected. The complexity in the inheritance pattern comes from the fact that these obligate carrier males (transmitting males) pass on the mutation to all their daughters (unaffected). most of the sons of carrier females with the mutation are mentally retarded but of their daughters, only 1/3 are retarded while 1/3 are borderline retarded and 1/3 are normal. Penetrance of the disease is variable within families and among siblings. Another unique characteristic of this syndrome, which is referred to as the Sherman Paradox is the fact that the risk of a family member being abnormal when gene-positive depends on the position of the proband in the pedigree. Sons of phenotypically normal but transmitting males have no risk of being mentally affected, but grandsons and great-grandsons of the transmitting a male have a much higher risk of mental retardation (40% and 50%, respectively). On the other hand, if the carrier female expresses the mental handicap her sons have a 50% risk of mental retardation. The classical method of confirming diagnosis is culture of lymphocytes in a folate-free medium (or supplemented with trimethoprim, methotrexate or FUdR) and microscopic detection of the fragile site (Xq27.3). Expression is seen in less than 50% of the cells of affected individuals but the test is not applicable to carrier detection as there is a high false negative rate (60%). The fragile-X gene (FMR-1), which contains tandemly repeated trinucleotide sequences (CGG repeats) on its 5' end, can be detected with PCR or Southern blot techniques. Normal controls show 6-50 CGG repeats, whereas mutation in affected males or heterozygous females can contain as many as 1,000 CGG repeat units. The test is indicated for individuals with compatible mental retardation, developmental delays or autism, or for those that have a family history of the syndrome. It is also indicated for prenatal detection in offspring of carrier females. Inheritance: sex-linked. Incidence: 1 in 1200 males and 1 in 2500 females. (17 Dec 1997) |
| fragilitas | Synonym: fragility. Origin: L. (05 Mar 2000) |
| fragilitas crinium | Brittleness of the hair; a condition in which the hair of the head or face tends to split or break off. (05 Mar 2000) |
| fragilitas sanguinis | The susceptibility, or lack of resistance, of erythrocytes to haemolysis when exposed to increasingly hypotonic saline solutions. (12 Dec 1998) |
| fragility | Brittleness; liability to break, burst, or disintegrate. Synonym: fragilitas. Origin: L. Fragilitas (05 Mar 2000) |
| fragility of the blood | The susceptibility, or lack of resistance, of erythrocytes to haemolysis when exposed to increasingly hypotonic saline solutions. (12 Dec 1998) |
| fragility test | A test that measures the resistance of erythrocytes to haemolysis in hypotonic saline solutions; erythrocytes to be tested are added to varying concentrations of saline (usually ranging from 0.85 to 0.10% sodium chloride with 0.05% increments), and beginning and complete haemolysis are measured; normal erythrocytes show initial haemolysis at concentrations of 0.45 to 0.39% and complete haemolysis at 0.33 to 0.30%; in hereditary spherocytosis the fragility of the erythrocytes is markedly increased, whereas in thalassaemia, sickle cell anaemia, and obstructive jaundice the fragility of the erythrocytes is usually reduced. Synonym: erythrocyte fragility test. (05 Mar 2000) |
Synonyms : Closed Fracture, Closed Fractures, Fracture, Closed, Fracture, Occult, Occult Fracture, Occult Fractures
Synonyms : Comminuted Fracture, Comminuted Fractures, Fracture, Comminuted
Synonyms : Compression Fractures, Compression Fracture, Fracture, Compression
Synonyms : Fractures, Abnormal Union, Fractures, Crossunited, Crossunited Fracture, Crossunited Fractures, Fracture, Abnormal Union, Fracture, Crossunited, Fracture, Malunited, Malunited Fracture, Malunited Fractures
Synonyms : Compound Fracture, Compound Fractures, Fracture, Compound, Fracture, Open, Open Fracture, Open Fractures
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| fractionate |
separate into constituents or fractions containing concentrated constituents obtain by a fractional process
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| fragmentation |
atomization: separating something into fine particles the disintegration of social norms governing behavior and thought and social relationships (computer science) the condition of a file that is broken up and stored in many different locations on a magnetic disk; "fragmentation slows system performance because it takes extra time to locate and assemble the parts of the fragmented file" the scattering of bomb fragments after the bomb explodes
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| frailty |
infirmity: the state of being weak in health or body (especially from old age) moral weakness
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| frambesia |
yaws: an infectious tropical disease resembling syphilis in its early stages; marked by red skin eruptions and ulcerating lesions
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| frame |
framework: a structure supporting or containing something enclose in a frame, as of a picture one of a series of still transparent photographs on a strip of film used in making movies human body: alternative names for the body of a human being; "Leonardo studied the human body"; "he has a strong physique"; "the spirit is willing but the flesh is weak" ensnare: take or catch as if in a snare or trap; "I was set up!"; "The innocent man was framed by the police" inning: a period of play in baseball during which each team has a turn at bat formulate in a particular style or language; "I wouldn't put it that way"; "She cast her request in very polite language" skeletal system: the hard structure (bones and cartilages) that provides a frame for the body of an animal make up plans or basic details for; "frame a policy" construct by fitting or uniting parts together skeleton: the internal supporting structure that gives an artifact its shape; "the building has a steel skeleton"
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| FRA | (geology) a crack in the earth's crust resulting from the displacement of one side with respect to the other |
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| FRA | breaking of hard tissue such as bone |
| FRA | fracture a bone of |
| FRA | break, as of a bone |
| FRA | become fractured |
| FRA | violate or abuse |
| FRA | break into pieces |
| FRA | interrupt, break, or destroy |
| FRA | used of a break or crack or tear in bone or cartilage |
| FRA | an antibiotic obtained from an actinomycete and used (as a sulphate |
| FRA | strawberries |
| FRA | widely cultivated |
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