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AGN acute glomerulonephritis; agnosia
APSGN acute poststreptococcal glomerulonephritis
CG cardiography; cardiogreen; choking gas; choriogenic gynecomastia; chorionic gonadotropin; chromogran...
CGN chronic glomerulonephritis
CMGN chronic membranous glomerulonephritis
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MPGN Membranoproliferative glomerulonephritis
MGN Membranous Glomerulonephritis
MesPGN Mesangial proliferative glomerulonephritis
MCGN Mesangiocapillary glomerulonephritis
PSGN Post-streptococcal glomerulonephritis
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immune complex glomerulonephritis Immune complexes are deposited in the renal glomerulus where they bind complement and initiate an inflammatory process attracting neutrophils and macrophages resulting in an alteration of the basement layer of the kidney. The disease state can lead to ultimate destruction of the glomerulus and renal failure.
(05 Mar 2000)
extramembranous glomerulonephritis <pathology> A kidney disease that occurs due to inflammation of the kidney glomerulus and its basement membrane. The exact cause is unknown but it appears to be related to the deposition of immune complexes in the basement membrane leading to thickening of the capillary walls. This disorder is a common cause of nephrotic syndrome an is usually how the disease manifests. Risk factors include primary renal disease, malaria, hepatitis B, lupus, syphilis, cancers and non-Hodgkin's lymphomas. Risks also include exposure to some medications such as gold compounds and penicillamine. Mercury, trimethadione and some skin-lightening creams have also been implicated.
Treatment includes systemic corticosteroids and immunosuppressive agents.
(27 Sep 1997)
exudative glomerulonephritis Glomerulonephritis with infiltration of glomeruli by polymorphonuclear leukocytes, occurring in acute glomerulonephritis.
(05 Mar 2000)
focal embolic glomerulonephritis Glomerulonephritis associated with subacute bacterial endocarditis, frequently producing microscopic haematuria without azotemia.
(05 Mar 2000)
focal glomerulonephritis Glomerulonephritis affecting a small proportion of renal glomeruli which commonly presents with haematuria and may be associated with acute upper respiratory infection in young males, not usually due to streptococci; associated with IgA deposits in the glomerular mesangium and may also be associated with systemic disease, as in Henoch-Schonlein purpura.
Synonym: Berger's disease, Berger's focal glomerulonephritis, focal nephritis, IgA nephropathy.
(05 Mar 2000)
lobular glomerulonephritis <pathology> A kidney disorder which results in kidney dysfunction. Inflammation of the glomeruli result from an abnormal immune response and the deposition of antibodies within the kidney (glomerulus) ultrastructure.
Membranoproliferative glomerulonephritis has been divided into two different types in the basis of where the antibodies are deposited in the glomerulus. MPGN type I, the more common type, deposits antibodies in the subendothelial layer of the basement membrane, whereas type II deposits antibodies in the bottom layer of the basement membrane.
Symptoms include cloudy urine (pyuria), decreased urine output, swelling and hypertension. This disorder often results in end-stage renal disease.
Acronym: MPGN
(26 Mar 1998)
local glomerulonephritis Glomerulonephritis affecting only part of a glomerulus or glomeruli.
Synonym: local glomerulonephritis.
(05 Mar 2000)
lupus glomerulonephritis-pathology Patient survival and preservation of renal function are predictable from renal pathology as demonstrated by biopsy and defined by the histological classification of the International Study of Kidney Disease in Children/World Health Organization (ISKDC/WHO). Semi-quantitative indices of nephron loss (chronicity index) and activity of acute potentially reversible inflammation (activity index) are not predictive of individual outcome, renal failure or death in patients with aggressively treated SLE GN.
(05 Mar 2000)
acrocephalosyndactyly type 1 <paediatrics> An inherited disease (autosomal dominant) or a spontaneously occurring disease characterised by a peaked head and unusual facial appearance, due to the premature closure of the cranial sutures.
A skull X-ray can confirm the diagnosis and treatment is surgical.
Inheritance: autosomal dominant.
(27 Sep 1997)
Alzheimer type I astrocyte Enlarged frequently multinucleated astrocytes, seen in progressive multifocal leukoencephalopathy.
(05 Mar 2000)
Alzheimer type II astrocyte Enlarged astrocytes with vesicular nuclei and one or more small basophilic nucleoli, seen in hepatocerebral disease and Wilson's disease.
(05 Mar 2000)
American Type Culture Collection <cell culture> A key resource for cultured cells, located in Rockville, USA.
(12 Dec 1998)
Antoni type A neurilemoma <tumour> Relatively solid or compact arrangement of neoplastic tissue that consists of Schwann cells arranged in twisting bundles and associated with delicate reticulin fibres; the nuclei of the Schwann cells are frequently grouped in parallel rows (so-called palisades), and the nuclei and fibres sometimes form exaggerated tactile corpuscles, called Verocay bodies.
(05 Mar 2000)
Antoni type B neurilemoma <tumour> Relatively soft or loose arrangement of neoplastic tissue that consists of Schwann cells in a haphazard or nondescript type of arrangement among reticulin fibres and tiny cystlike foci; fat-laden macrophages may be observed in some of the larger neoplasms.
(05 Mar 2000)
arthus-type reaction's Reaction's in man and other species that result from the same basic immunologic (allergic) mechanism which evokes, in the rabbit, the typical Arthus phenomenon.
See: immune complex disease.
(05 Mar 2000)
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