| dihydrofolate monooxygenase | <enzyme> 7,8-dihydrofolate plus 1/2 o2 gives 7,8-dihydropterin-6-aldehyde plus p-aminobenzoylglutamate Registry number: EC 1.13.- (26 Jun 1999) |
|---|---|
| dihydrofolate reductase | <enzyme> An enzyme involved in the biosynthesis of folic acid coenzymes, that transfers hydrogen from NADP to dihydrofolate, yielding tetrahydrofolic acid. Inhibitors can be used as antimicrobial and anticancer drugs. Standard source is liver and the enzyme is used to assay dihydrofolate. (18 Nov 1997) |
| dihydrogen phosphate | One-third-neutralised phosphoric acid; e.g., NaH2PO4, KH2PO4. Disodium phosphate, na2HPO4. (05 Mar 2000) |
| dihydrogeodin oxidase | <enzyme> Copper-containing enzyme which converts dihydrogeodin to (+)-geodin by an intramolecular phenol oxidative coupling reaction; isolated from aspergillus terreus Registry number: EC 1.10.3.- (26 Jun 1999) |
| dihydrolipoamide acetyltransferase | <enzyme> Part of the pyruvate dehydrogenase complex; acef isolated from e. Coli Registry number: EC 2.3.1.12 Synonym: dihydrolipoyl transacetylase, lipoate acetyltransferase, dihydrolipoyl acetyltransferase, acef gene product (26 Jun 1999) |
| dihydrolipoamide acyltransferase | <enzyme> Component of branched-chain 2-oxo acid dehydrogenase multienzyme complex; mutation in this (e2) catalytic subunit identifies type II maple syrup urine disease Registry number: EC 2.3.1.- Synonym: dihydrolipoyl transacylase, branched chain acyltransferase, e2 transacylase (26 Jun 1999) |
| dihydrolipoamide dehydrogenase | <enzyme> An enzyme oxidizing dihydrolipoamide at the expense of NAD+; completes the oxidative decarboxylation of pyruvate; a part of several enzyme complexes (e.g., alpha-ketoglutarate dehydrogenase complex). Decreased activity leads to neuronal loss in brain resulting in psychomotor retardation. Synonym: coenzyme factor, lipoamide dehydrogenase, lipoamide reductase (NADH), lipoyl dehydrogenase. (05 Mar 2000) |
| dihydrolipoamide succinyltransferase | <enzyme> Component of the ketoglutarate dehydrogenase complex Registry number: EC 2.3.1.61 Synonym: succinyl-CoA-dihydrolipoate-s-succinyltransferase, dihydrolipoyl transsuccinylase, lipoyl transsuccinylase, lipoate succinyltransferase, lipoamide succinyltransferase, succinyl-coenzyme a-dihydrolipoate-s-succinyltransferase (26 Jun 1999) |
| dihydrolipoic acid | Reduced lipoic acid, formed by cleavage of the -S-S- bond as a result of the acceptance of two hydrogens. Compare: lipoic acid. (05 Mar 2000) |
| dihydromorphine | <chemical> 4,5-epoxy-17-methylmorphinan-3,6-alpha-diol. A semisynthetic analgesic used in the study of narcotic receptors. It has abuse potential. Pharmacological action: analgesics, opioid, narcotics. Chemical name: Morphinan-3,6-diol, 4,5-epoxy-17-methyl-, (5alpha,6alpha)- (12 Dec 1998) |
| dihydromorphinone hydrochloride | A synthetic derivative of morphine, with analgesic potency about 10 times that of morphine. Synonym: dihydromorphinone hydrochloride. (05 Mar 2000) |
| dihydroneopterin triphosphate pyrophosphohydrolase | <enzyme> Human liver enzyme removes triphosphate to give 6-pyruvoyl-tetrahydrobiopterin Registry number: EC 3.6.1.- Synonym: 7,8-dihydroneopterin triphosphate phosphate eliminating enzyme, phosphate eliminating enzyme (26 Jun 1999) |
| dihydroorotase | <enzyme> An enzyme that, in the course of pyrimidine biosynthesis, catalyses ring closure by removal of water from N-carbamoyl-l-aspartate to form l-5,6-dihydroorotate (dihydro-orotic acid). Synonym: carbamoylaspartate dehydrase. Chemical name: (S)-Dihydroorotate amidohydrolase Registry number: EC 3.5.2.3 (21 Jun 2000) |
| dihydroorotate dehydrogenase | <enzyme> Converts (s)-dihydroorotate and an aceptor to orotate and a reducted aceptor; dihydro-orotate dehydrogenase was see dihydro-orotate oxidase 1977-93 Registry number: EC 1.3.99.11 Synonym: dihydro-orotate-cytochrome c reductase, dihydro-orotate dehydrogenase (26 Jun 1999) |
| dihydroorotate hydroxylase | <enzyme> A pteridine-requiring enzyme Registry number: EC 1.14.16.- (26 Jun 1999) |