| MCDU | mercaptolactate-cysteine disulfiduria |
|---|---|
| SPARC | cysteine-rich acidic secreted protein |
| catechol 2,3-dioxygenase | <enzyme> An oxidoreductase oxidizing catechol, with oxygen, to 2-hydroxymuconate saemialdehyde. Synonym: metapyrocatechase. (05 Mar 2000) |
|---|---|
| peptide-tryptophan 2,3-dioxygenase | <enzyme> Catalyses the oxidation of peptide tryptophan to form peptide formylkynurenine Registry number: EC 1.13.11.26 Synonym: tryptophan pyrrolooxygenase (26 Jun 1999) |
| chlorobenzene dioxygenase | <enzyme> With chlorobenzene dioxygenase catalyses chlorobenzenes to chlorocatechols Registry number: EC 1.13.99.- (26 Jun 1999) |
| chlorocatechol 1,2-dioxygenase | <enzyme> Forms 2,4-dichloromuconate Registry number: EC 1.13.11.- (26 Jun 1999) |
| phenoxybenzoate dioxygenase | <enzyme> Catalyses conversion of 3- or 4-phenoxybenzoate to phenol and protocatechuate via a putative hemiacetal intermediate. Registry number: EC 1.14.14.- Synonym: 4-carboxydiphenyl ether dioxygenase, pob dioxygenase, pobb gene product (26 Jun 1999) |
| phthalate dioxygenase | <enzyme> Iron-sulfur protein from pseudomonas (burkholderia) cepacia; dihydroxylates phthalate to its 4,5-dihydrodiol; contains a flavo-iron-sulfur protein with NADH-dependent oxidoreductase activity and a non-haem iron protein with oxygenase activity Registry number: EC 1.14.99.- Synonym: phthalate oxygenase, phthalate 4,5-dioxygenase (26 Jun 1999) |
| procollagen-lysine, 2-oxoglutarate 5-dioxygenase | <enzyme> A mixed-function oxygenase that catalyses the hydroxylation of peptidyllysine, usually in protocollagen, to peptidylhydroxylysine. The enzyme utilises molecular oxygen with concomitant oxidative decarboxylation of the cosubstrate 2-oxoglutarate to succinate. Chemical name: Procollagen-L-lysine,2-oxoglutarate:oxygen oxidoreductase (5-hydroxylating) Registry number: EC 1.14.11.4 (12 Dec 1998) |
| procollagen-proline dioxygenase | <enzyme> A mixed-function oxygenase that catalyses the hydroxylation of a prolyl-glycyl-containing-peptide, usually in protocollagen, to a hydroxyprolylglycyl-containing-peptide. The enzyme utilises molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. Chemical name: Procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase Registry number: EC 1.14.11.2 (12 Dec 1998) |
| proline, 2-oxoglutarate 3-dioxygenase | <enzyme> Prolyl 3-hydroxylase is separate enzyme from prolyl 4-hydroxylase; catalyses post translational modification of collagen Registry number: EC 1.14.11.7 Synonym: proline 3-hydroxylase, prolyl 3-hydroxylase (26 Jun 1999) |
| protocatechuate 2,3-dioxygenase | <enzyme> From bacillus macerans; catalyses the conversion of protocatechuate to alpha-hydroxy-delta-carboxymuconic saemialdehyde in the presence of oxygen Registry number: EC 1.13.11.- (26 Jun 1999) |
| protocatechuate-3,4-dioxygenase | <enzyme> An enzyme that catalyses the oxidation of protocatechuate to 3-carboxy-cis-cis-muconate in the presence of molecular oxygen. It contains ferric ion. Chemical name: Protocatechuate:oxygen 3,4-oxidoreductase (decyclizing) Registry number: EC 1.13.11.3 (12 Dec 1998) |
| homogentisate 1,2-dioxygenase | An iron-containing enzyme that catalyses the oxidative cleavage of the benzene ring in homogentisic acid by O2, forming 4-maleylacetoacetate; an absence or deficiency of this enzyme will result in alcaptonuria. Synonym: homogentisic acid oxidase. (05 Mar 2000) |
| hydroxyquinol 1,2-dioxygenase | <enzyme> Catalyses oxidative ring fission of hydroxyquinol to yield 3-hydroxy-cis,cis-muconate; contains ferric iron; specific for hydroxyquinol Registry number: EC 1.13.11.- Synonym: 1,2,4-trihydroxybenzene 1,2-dioxygenase (26 Jun 1999) |
| hyoscyamine (6S)-dioxygenase | <enzyme> A 2-oxoglutarate-dependent dioxygenase that catalyses hydroxylation of l-hyoscyamine to 6beta-hydroxyhyoscyamine in biosynthetic pathway to scopolamine; requires fe2+ Registry number: EC 1.14.11.11 Synonym: hyoscyamine 6beta-hydroxylase, hyoscyamine 6 beta-hydroxylase (26 Jun 1999) |
| naphthalene dioxygenase | <enzyme> Forms cis-(1r,2s)-dihydroxy-1,2-dihydronaphthalene; requires NADH Registry number: EC 1.14.12.- (26 Jun 1999) |