| coapt | To join or fit together. (05 Mar 2000) |
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| coaptation | Joining or fitting together of two surfaces; e.g., the lips of a wound or the ends of a broken bone. Origin: L. Co-apto, pp. -aptatus, to fit together (05 Mar 2000) |
| coaptation splint | A short splint designed to prevent overriding of the ends of a fractured bone, usually supplemented by a longer splint to fix the entire limb. (05 Mar 2000) |
| coaptation suture | A suture of the skin only. Synonym: coaptation suture. (05 Mar 2000) |
| coarct | To restrict or press together. Synonym: coarctate. Origin: L. Co-arcto, pp. -arctatus, to press together (05 Mar 2000) |
| coarctate | Synonym: coarct. 2. Pressed together. (05 Mar 2000) |
| coarctate retina | An obsolete term for a ringlike effusion of fluid between the choroid and retina, giving the latter a funnel shape. (05 Mar 2000) |
| coarctation | <cardiology, embryology> A narrowing of the passageway of a blood vessel, such as coarctation of the aorta, a congenital condition. (27 Sep 1997) |
| coarctation of the aorta | <cardiology, embryology, paediatrics> A congenital heart defect that results in the narrowing of the lumen of the aorta. The narrowing occurs most often distal to the origin of the left subclavian artery. Coarctation occurs in approximately 7% of patients with congenital heart disease and is twice as common in males. Surgical correction is most often required. Symptoms include headaches, dizziness, fainting, nosebleeds, diminished pulses in lower extremities and muscle cramps in legs with activity. There may be no symptoms in some individuals. (27 Sep 1997) |
| coarctectomy | Excision of a coarctation (of the aorta). (05 Mar 2000) |
| coarctotomy | Division of a stricture. Origin: coarct + G. Tome, cutting (05 Mar 2000) |
| coarse breast architecture | <radiology> Inflammatory carcinoma, other lymphatic spread of tumour, oedema, congestive heart failure, uraemia, drug-induced, radiation, mastitis (12 Dec 1998) |
| coarse dispersion | 1. A condition of temporary cessation, as of animation, of pain or of any vital process. 2. <pharmacology> A preparation of a finely divided drug intended to be incorporated (suspended) in some suitable liquid vehicle before it is used or already incorporated in such a vehicle. Origin: L. Suspensio (18 Nov 1997) |
| coarse tremor | A tremor in which the amplitude is large and the oscillations are usually irregular and slow. (05 Mar 2000) |
| CoAS- | Symbols for the coenzyme A radical and reduced coenzyme A, respectively. (05 Mar 2000) |
| acyl-CoA | RCH2COSCoA or RCH2CO~SCoA;condensation product of a carboxylic acid and coenzyme A, and metabolic intermediate of importance, notably in the oxidation and synthesis of fat. Synonym: acyl-coenzyme A. (05 Mar 2000) |
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| acyl-CoA-1-O-alkyl-2-acetyl-sn-glycerol acyltransferase | <enzyme> From hl-60 cells; related to platelet-activating factor metabolism Registry number: EC 2.3.1.- Synonym: acyl-CoA-1-o-hexadecyl-2-acetyl-sn-glycerol acyltransferase, acaag-acyltransferase, acyl-coenzyme a-1-o-alkyl-2-acetyl-sn-glycerol acyltransferase (26 Jun 1999) |
| acyl-CoA-6-aminopenicillanic acid acyltransferase | <enzyme> Acyl CoA and aminopenicillanic acid yield penicillin and CoA Registry number: EC 2.3.1.- Synonym: 6-apa acyltransferase, 6-aminopenicillanic acid-phenacetyl-CoA-phenoxyacetyl-CoA transferase, acyl-coenzyme a-6-aminopenicillanic acid acyltransferase, isopenicillin n-phenylacetyl-CoA acyltransferase, penicillin acyltransferase, isopenicillin n-phenylacetyl-coenzyme a acyltransferase, acyl-CoA-ipn acyltransferase, isopenicillin n acyltransferase, aat gene product, pende gene product (26 Jun 1999) |
| acyl-CoA carboxylase | <enzyme> Catalyses carboxylation (ATP, mg ++, mco(3)-dependent) of acetyl-CoA, propionyl CoA, and butyryl CoA; from nematode turbatrix aceti Registry number: EC 6.4.1.- Synonym: acyl-coenzyme a carboxylase (26 Jun 1999) |
| acyl-CoA dehydrogenase | <enzyme> See also records for specific fatty acyl groups which have full EC nomenclature number; electron-transferring flavoprotein system reducing ubiquinone and other acceptors; formerly EC 1.3.2.2 Registry number: EC 1.3.99.3 Synonym: fatty-acyl CoA dehydrogenase, palmitoyl-CoA dehydrogenase, short-chain acyl-CoA dehydrogenase, acyl-coenzyme a dehydrogenase, lauroyl-CoA oxidase (26 Jun 1999) |
| acyl-CoA dehydrogenase (NADPH+) | Enzyme catalyzing the reversible reduction of enoyl-CoA derivatives of chain length 4 to 16, with NADPH as the hydrogen donor, forming acyl-CoA and NADP+. Synonym: enoyl-CoA reductase. (05 Mar 2000) |
| acyl-CoA-diol transacylase | <enzyme> Catalyses stepwise acylation of alkane-2,3-diols to give the diol ester which constitutes the major component of uropygial lipids of ring-necked pheasants Registry number: EC 2.3.1.- Synonym: acyl-coenzyme a-diol transacylase (26 Jun 1999) |
| acyl-CoA-estradiol-17-beta-acyltransferase | <enzyme> Catalyses the esterification of estradiol with long chain fatty acids at the 17-position Registry number: EC 2.3.1.- Synonym: acylcoenzyme a-estradiol-17-beta-acyltransferase, estradiol 17-acyltransferase (26 Jun 1999) |
| acyl-CoA oxidase | <enzyme> Catalyses stoichiometric conversion of palmitoyl-CoA and o2 into 2-hexadecenoyl-CoA and h2o2; oxidises acyl-CoA's with carbon chain lengths of 4 to 20; most active toward lauroyl-CoA, but not acetyl- or succinyl-CoA Registry number: EC 1.3.3.6 Synonym: fatty acyl CoA oxidase, fatty acyl-coenzyme a oxidase, fatty acid acyl-CoA oxidase, acox, pox1 gene product (26 Jun 1999) |
| acyl-CoA sterol acyltransferase | <enzyme> Isolated from saccharomyces cerevisiae; sat1 and sat2 are isoenzymes; genbank u55383 Registry number: EC 2.3.1- Synonym: sat1 gene product, sat2 gene product (26 Jun 1999) |
| acyl-CoA synthetase | General term for enzymes that form acyl-CoA, now called ligases, specifically, long-chain fatty acid-CoA ligase. (05 Mar 2000) |
| acyl-CoA transferase | <enzyme> Transfers CoA from succinyl-CoA to propionate, forming propionyl-CoA plus succinate Registry number: EC 2.8.3.- Synonym: propionate CoA-transferase, acyl-coenzyme a transferase (26 Jun 1999) |
| acyl-CoA triterpene acyltransferase | <enzyme> Catalyses the esterification of triterpenes with a fatty acid; requires either acetyl-CoA, ATP, and fatty acid, or fatty acyl-CoA alone Registry number: EC 2.3.1.- Synonym: actt-acyltransferase (26 Jun 1999) |
| alpha-methylacyl-CoA racemase | <enzyme> Involved in catabolism of branched-chain fatty acids derived from isoprenoids; acts on pristanoyl-CoA and trihydroxycoprostanoyl-CoA, but not on 3-methyl branched-chain or linear-chain acyl coas; amino acid sequence has been determined; genbank u89905 (rat) and u89906 (mouse); also isolated from human liver Registry number: EC 5.1.99.- Synonym: meac CoA racemase (26 Jun 1999) |
| aralkyl-CoA-glycine N-acyltransferase | <enzyme> Involved in conjugation of xenobiotics such as substituted benzoic acids or medium chain fatty-acyl-coas with glycine; n-terminal amino acid sequence given in first source Registry number: EC 2.3.1.- Synonym: aralkyltransferase, aralkyl-CoA-glycine n-glycyltransferase (26 Jun 1999) |