| DipChem | Diploma in Chemistry |
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| DPhC | Doctor of Pharmaceutical Chemistry |
| IUPAC | International Union of Pure and Applied Chemistry |
| RIC | right internal carotid [artery]; Royal Institute of Chemistry |
| SCG | serum chemistry graft; serum chemogram; sodium cromoglycate; superior cervical ganglion |
| phase I clinical trial | <pharmacology> The earliest stage clinical trial for studying an experimental drug in humans. Phase I trials are generally comparatively small and are used to determine toxicity and maximum dose. They provide an initial evaluation of a drug's safety and pharmacokinetics-how the drug is absorbed, what tissues it reaches and how long it takes to leave the body. Such studies also usually test various doses of the drug (dose-ranging) to obtain an indication of the appropriate dose to use in later studies. The patients in these trials usually have advanced disease and have already received best available chemotherapy, therefore, seeing a repose is significant partially because this means there is a lack of cross-resistance between two anti-cancer drugs. (31 Dec 1997) |
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| phase II clinical trial | <pharmacology> Usually focus on the activity of the new product as a single agent in a noncomparative, open study. (31 Dec 1997) |
| phase III clinical trial | <pharmacology> An advanced stage clinical trial that should conclusively show how well a drug works as compared to other treatments. Phase III trials are large, frequently multi-institution tests. They generally compare the relative value of the new drug compared with the current standard treatment and measure whether a new drug extends survival or otherwise improves the health of patients on treatment (clinical improvement) rather than just provide surrogate marker data. These studies generally last longer and are larger than phase II trials. (31 Dec 1997) |
| Millon clinical multiaxial inventory | A paper and pencil test, consisting of 20 clinical scales derived from 175 self-descriptive statements, and developed in 1977 for use in the assessment of psychopathology and the more enduring patterns of personality; specifically designed to correspond with some of the disorders of personality included in the Diagnostic and Statistical Manual of Mental Disorders used in diagnosis by mental health professionals. Synonym: Millon clinical multiaxial inventory. (05 Mar 2000) |
| Millon Clinical Multiaxial Inventory test | A paper and pencil test, consisting of 20 clinical scales derived from 175 self-descriptive statements, and developed in 1977 for use in the assessment of psychopathology and the more enduring patterns of personality; specifically designed to correspond with some of the disorders of personality included in the Diagnostic and Statistical Manual of Mental Disorders used in diagnosis by mental health professionals. Synonym: Millon clinical multiaxial inventory. (05 Mar 2000) |
| clinical | 1. Pertaining to a clinic or to the bedside. 2. Pertaining to or founded on actual observation and treatment of patients, as distinguished from theoretical or basis sciences. (18 Nov 1997) |
| clinical anatomy | The practical application of anatomical knowledge to diagnosis and treatment. Synonym: applied anatomy. (05 Mar 2000) |
| clinical burden | A burden that differs from genetic burden mainly in the added component of morbidity; a trait that is neither a clinical or a genetic lethal may be grossly disabling. (05 Mar 2000) |
| clinical clerkship | Undergraduate medical education programs for second- , third- , and fourth-year students in which the students receive clinical training and experience in teaching hospitals or affiliated health centres. (12 Dec 1998) |
| clinical competence | The capability to perform acceptably those duties directly related to patient care. (12 Dec 1998) |
| clinical conference | A conference of physicians on their observations of a patient at the bedside, regarding the physical state, laboratory and other diagnostic findings, clinical manifestations, results of current therapy, etc. A clinical conference usually ends with a confirmation or correction of clinical findings by a pathological diagnosis performed by a pathologist. "clinical conference" is often referred to as a "clinico-pathological conference." (12 Dec 1998) |
| clinical cooperative group | A group of medical institutions cooperating to perform clinical research. (16 Dec 1997) |
| clinical crown | That part of the crown of a tooth visible in the oral cavity. Synonym: corona clinica. (05 Mar 2000) |
| clinical cytogenetics | The application of chromosome studies to clinical medicine. For example, clinical cytogenetic testing is done to see if a child with possible Down syndrome has an extra chromosome 21, as is most often the case. Clinical Cytogenetics is a specialty certified by the American Board Of Medical Genetics. (12 Dec 1998) |
| clinical depression | <psychiatry> A clinical syndrome that includes a persistent sad mood or loss of interest in activities that persists for at least 2 weeks in the absence of external precipitants. This should not be confused with a grief reaction (death of loved one). Features may include change in eating habits, insomnia, early morning wakening, lack of interest, depressed mood, fatigue and suicidal thoughts. (27 Sep 1997) |