| 영문 | reserve cell | 한글 | 예비세포 |
|---|---|---|---|
| 설명 | 일반적으로 상피조직에서 이미 있던 상피세포가 손상을 받아 사멸하면 매꿔지는 그 밑에 있는 미분화세포 예를 들면, 기관지 내표면을 덮는 중층 원주 상피의 기저에 있는 작은 미분화 상피 세포. |
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| 영문 | stem cell | 한글 | 줄기세포, 간세포 |
|---|---|---|---|
| 설명 | 자기 복제를 하여 자신을 존속시키면서 한편으로는 증식과 분화를 하여 새로운 세포를 형성하는 세포로서 조혈줄기세포가 대표적이다. 조혈줄기세포는 골수에 있는 세포로서 모든 혈구세포가 여기에서 분화되어 발생한다. |
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| 영문 | renal cell carcinoma | 한글 | 콩팥세포암종 |
|---|---|---|---|
| 설명 | 콩팥에 생긴 원시콩팥조직에서 발생한 암. 주로 원시세뇨관조직에서 발생한다. 대표적인 세포조직형은 염색시 세포질이 맑게 비어보이는 맑은세포암종이다. 치료는 수술과 항암화학요법이며 아주 드물지만 저절로 낫는 경우도 있는 것으로 보고되어 있다. |
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| 영문 | squamous cell carcinoma | 한글 | 편평세포암종 |
|---|---|---|---|
| 설명 | 편평세포 기원의 암으로서, 편평세포가 있는 어떤 곳에서든 발생가능함. 따라서 식도암, 피부암, 폐암, 자궁암 등이 여기에 해당된다. 특히 피부암은 많은 자외선조사에 의해 생기는 광선각화증에서 발생가능하다. 병리조직학적 특성으로서 각질을 생성한다. |
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| CML | carboxymethyl lysine; cell-mediated lymphocytotoxicity; cell-mediated lympholysis; central motor lat... |
|---|---|
| ACC | accommodation; acetyl coenzyme A carboxylase; acinic cell carcinoma; acute care center; adenoid cyst... |
| CPH | Certificate in Public Health; chronic paroxysmal hemicrania; chronic persistent hepatitis; chronic p... |
| CCH | C-cell hyperplasia; chronic chloride hemagglutination; chronic cholestatic hepatitis |
| CCS | Canadian Cardiovascular Society; casualty clearing station; cell cycle specific; cholecystosonograph... |
| acute myeloblastic leukaemia | <haematology> A rapidly progressing cancer of the blood affecting immature cells of the bone marrow, usually of the white cell population. It is much more common in adults than in children. Symptoms include fatigue, weight loss, fevers, weakness, pallor, bone pains, bleeding gums, nosebleeds, easy bruising, enlarged lymph nodes and joint pains. Treatment includes chemotherapy and/or bone marrow transplant. This leukaemia demonstrates granulocyte differentiation, eosinophilia and Auer rods and is associated with a reciprocal translocation between 8 and 21 (q22;q22), which is the most common translocation in acute myeloid leukaemia and is found more often in younger patients than in older patients. The oncogene involved in this translocation is AML1, which can be detected by Southern blot. Numerical abnormalities, particularly monosomy-7, trisomy-4, trisomy-8, trisomy-21, -Y, monosomy-7 and deletions of the long arms of chromosomes 5 and 7 are quite common in all acute myeloid leukaemia and not restricted to any one FAB classification. Many of these abnormalities are observed at diagnosis and at later stage disease, particularly after chemotherapy. Prognosis is generally more favorable than in FAB-M2 patients showing no translocation, because the latter patients show better remission rates for longer periods of time. Immunophenotyping is useful in diagnosis and expression of one or more of the myeloid antigens CD13, CD14 or CD33 must be detected to make a diagnosis of acute myeloid leukaemia. Acronym: AML Incidence: 2,000 new cases per year in the UK. Origin: Gr. Haima = blood (07 Apr 1998) |
|---|---|
| acute myelogenous leukaemia | <haematology> A rapidly progressing cancer of the blood affecting immature cells of the bone marrow, usually of the white cell population. It is much more common in adults than in children. Symptoms include fatigue, weight loss, fevers, weakness, pallor, bone pains, bleeding gums, nosebleeds, easy bruising, enlarged lymph nodes and joint pains. Treatment includes chemotherapy and/or bone marrow transplant. This leukaemia demonstrates granulocyte differentiation, eosinophilia and Auer rods and is associated with a reciprocal translocation between 8 and 21 (q22;q22), which is the most common translocation in acute myeloid leukaemia and is found more often in younger patients than in older patients. The oncogene involved in this translocation is AML1, which can be detected by Southern blot. Numerical abnormalities, particularly monosomy-7, trisomy-4, trisomy-8, trisomy-21, -Y, monosomy-7 and deletions of the long arms of chromosomes 5 and 7 are quite common in all acute myeloid leukaemia and not restricted to any one FAB classification. Many of these abnormalities are observed at diagnosis and at later stage disease, particularly after chemotherapy. Prognosis is generally more favorable than in FAB-M2 patients showing no translocation, because the latter patients show better remission rates for longer periods of time. Immunophenotyping is useful in diagnosis and expression of one or more of the myeloid antigens CD13, CD14 or CD33 must be detected to make a diagnosis of acute myeloid leukaemia. Acronym: AML Incidence: 2,000 new cases per year in the UK. Origin: Gr. Haima = blood (07 Apr 1998) |
| acute myeloid leukaemia | <haematology> A rapidly progressing cancer of the blood affecting immature cells of the bone marrow, usually of the white cell population. It is much more common in adults than in children. Symptoms include fatigue, weight loss, fevers, weakness, pallor, bone pains, bleeding gums, nosebleeds, easy bruising, enlarged lymph nodes and joint pains. Treatment includes chemotherapy and/or bone marrow transplant. This leukaemia demonstrates granulocyte differentiation, eosinophilia and Auer rods and is associated with a reciprocal translocation between 8 and 21 (q22;q22), which is the most common translocation in acute myeloid leukaemia and is found more often in younger patients than in older patients. The oncogene involved in this translocation is AML1, which can be detected by Southern blot. Numerical abnormalities, particularly monosomy-7, trisomy-4, trisomy-8, trisomy-21, -Y, monosomy-7 and deletions of the long arms of chromosomes 5 and 7 are quite common in all acute myeloid leukaemia and not restricted to any one FAB classification. Many of these abnormalities are observed at diagnosis and at later stage disease, particularly after chemotherapy. Prognosis is generally more favorable than in FAB-M2 patients showing no translocation, because the latter patients show better remission rates for longer periods of time. Immunophenotyping is useful in diagnosis and expression of one or more of the myeloid antigens CD13, CD14 or CD33 must be detected to make a diagnosis of acute myeloid leukaemia. Acronym: AML Incidence: 2,000 new cases per year in the UK. Origin: Gr. Haima = blood (07 Apr 1998) |
| acute non-lymphocytic leukaemia | <haematology> A form of leukaemia which is characterised by the proliferation of immature bone marrow precursor cells in the marrow and immature white blood cells (granulocytes) in the bloodstream. Occurs primarily in adults and in infants under 1 year of age. Complications include abnormal bleeding and susceptibility to infections. Symptoms include fatigue, weight loss, fevers, weakness, pallor, bone pains, bleeding gums, nosebleeds, easy bruising, enlarged lymph nodes and joint pains. Trisomy-8 is the most common cytogenetic abnormality observed, followed by monosomy-7 and monosomy-5. Approximately 8% of cases show trisomy-8, mostly in AML (M1), AM (M4) and acute monocytic leukaemia (M5). Many pre-leukaemic conditions, acute non-lymphocytic leukaemia and secondary leukemia show monosomy-7 or deletion of the long arm of chromosome 7. Treatment includes chemotherapy and/or bone marrow transplant. Acronym: ANLL Incidence: 2.5 cases per 100,000 (all ages). Origin: Gr. Haima = blood (07 Apr 1998) |
| acute promyelocytic leukaemia | Leukaemia presenting as a severe bleeding disorder, with infiltration of the bone marrow by abnormal promyelocytes and myelocytes, a low plasma fibrinogen, and defective coagulation. (05 Mar 2000) |
| aleukaemic leukaemia | Leukaemia in which abnormal (or leukaemic) cells are absent in the peripheral blood. (05 Mar 2000) |
| avian leukaemia-sarcoma complex | A term applied to a group of transmissible virus-induced diseases of chickens causing sarcoma, myeloblastosis, erythroblastosis, leukosis, osteopetrosis, and lymphomatosis. These agents are closely related viruses (avian leukosis-sarcoma virus) causing prolferation of immature erythroid, myeloid, or lymphoid cells, a division of the RNA tumour viruses (subfamily Oncovirinae) causing the avian leukosis-sarcoma complex of diseases; the viruses are subgrouped according to antigenic characteristics and growth in defined types of tissue culture cells. Synonym: avian erythroblastosis virus, avian leukosis-sarcoma virus, avian lymphomatosis virus, avian myeloblastosis virus, avian sarcoma virus, fowl erythroblastosis virus, fowl lymphomatosis virus, fowl myeloblastosis virus. (05 Mar 2000) |
| avian leukaemia virus | <virology> Group of C type RNA tumour viruses (Oncovirinae) that cause various leukaemias and other tumours in birds. The acute leukaemia viruses, that are replication defective and require helper viruses, include avian erythroblastosis (AEV), myeloblastosis (AMV) and myelo cytomatosis viruses. AEV carries two transforming genes, v erbA and v erbB, the cellular homologue of the latter is the structural gene for the epidermal growth factor receptor. AMV carries v myb and causes a myeloid leukaemia, avian myelocytomatosis virus carries v myc. The avian lymphatic leukaemia viruses (ALV) are also Retroviridae but are replication competent and induce neoplasia only after several months, they often occur in conjunction with replication defective leukaemia viruses. (02 Jan 1998) |
| basophilic leukaemia | A form of granulocytic leukaemia in which there are unusually great numbers of basophilic granulocytes in the tissues and circulating blood; in some instances, the immature and mature basophilic forms may represent from 40 to 80% of the total numbers of white blood cells. Synonym: mast cell leukaemia. (05 Mar 2000) |
| bovine leukaemia | A lymphoid neoplastic disease in cattle caused by the bovine leukaemia virus. Enzootic bovine leukosis may take the form of lymphosarcoma, malignant lymphoma, or leukaemia but the presence of malignant cells in the blood is not a consistent finding. (12 Dec 1998) |
| bovine leukaemia virus | A type C retrovirus in the subfamily Retrovirinae, commonly infecting cattle, especially dairy cows; in a small proportion of infected cattle, it will cause enzootic bovine leukosis. Synonym: bovine leukosis virus. (05 Mar 2000) |
| cancer, leukaemia | Leukaemia is a cancer of the white blood cells. Leukaemias are grouped by how quickly the disease develops (acute or chronic) as well as by the type of blood cell that is affected. People with leukaemia are at significantly increased risk for developing infections, anaemia, and bleeding. Diagnosis of leukaemia is supported by findings of the medical history and examination, and examining blood under a microscope. Leukaemia cells can be detected and further classified with a bone marrow aspiration and/or biopsy. most patients with leukaemia are treated with chemotherapy. Some patients also may have radiation therapy and/or bone marrow transplantation. (12 Dec 1998) |
| radiation leukaemia virus | A murine leukaemia virus isolated from radiation-induced lymphomas in c57bl mice. It is leukemogenic, thymotrophic, can be transmitted vertically, and replicates only in vivo. (12 Dec 1998) |
| Maloney leukaemia virus | A retrovirus associated with leukaemia in rodents. (05 Mar 2000) |
| Rauscher leukaemia virus | An RNA retrovirus associated with leukaemia in rodents; similar to Friend virus. Synonym: Rauscher's virus. (05 Mar 2000) |