| ldl cholesterol | Low-density lipoprotein cholesterol (the bad cholesterol). (12 Dec 1998) |
|---|---|
| lecithin-cholesterol acyltransferase | <enzyme> An enzyme that reversibly transfers an acyl residue from a lecithin to cholesterol, forming a 1-acylglycerophosphocholine (a lysolecithin) and a cholesterol ester; a deficiency of this enzyme leads to an accumulation of unesterified cholesterol in plasma resulting in anaemia, proteinuria, renal failure, and corneal opacities; LCAT is also low in individuals with fish-eye disease. Synonym: lecithin acyltransferase. Acronym: LCAT (05 Mar 2000) |
| lecithin-cholesterol transferase | A plasma enzyme that catalyses the uptake of cholesterol esters by intermediate-density lipoproteins formed by high density lipoproteins. (05 Mar 2000) |
| lipoproteins, hdl cholesterol | Cholesterol which is contained in or bound to high density lipoproteins (hdl). High density lipoproteins transport cholesterol from peripheral tissues to the liver thereby acting as a scavenger to prevent excess accumulation and deposition of cholesterol in blood vessels. (12 Dec 1998) |
| lipoproteins, ldl cholesterol | Cholesterol which is contained in or bound to low density lipoproteins (ldl). Ldl transport cholesterol to peripheral tissues and regulate de novo cholesterol synthesis at these sites. Atherosclerosis is caused by the deposit of cholesterol on the walls of blood vessels, because of high concentrations of ldl cholesterol in plasma. (12 Dec 1998) |
| lipoproteins, vldl cholesterol | Cholesterol which is contained in or bound to very low density lipoproteins (vldl). High concentrations of vldl cholesterol are found in type IIb and type v hyperlipoproteinaemia. The end product of vldl cholesterol catabolism is ldl (low density lipoproteins). (12 Dec 1998) |
| abnormal cleavage of cardiac valve | Congenital malformation of a valve leaflet with a defect extending from the free margin. (05 Mar 2000) |
| adequal cleavage | Cleavage resulting in the formation of blastomeres of approximately equal size. (05 Mar 2000) |
| anterior chamber cleavage syndrome | <syndrome> A congenital disorder originating from faulty separation of embryonic structures; it results in bilateral central corneal opacities, with an anterior ring attachment of the iridic pupillary border and anterior polar cataracts; associated with short-limbed dwarfism; autosomal dominant inheritance. See: iridocorneal endothelial syndrome. Synonym: Peters' anomaly. (05 Mar 2000) |
| glycine cleavage complex | A complex of several proteins that catalyze the reversible reaction of glycine with tetrahydrofolate to produce CO2, NH3, and N5,N10-methylenetetrahydrofolate; a deficiency of this enzyme (or one of its subunits) will result in nonketotic hyperglycinaemia. Synonym: glycine synthase. (05 Mar 2000) |
| meridional cleavage | Cleavage in a plane through the axis of the zygote. (05 Mar 2000) |
| meroblastic cleavage | Incomplete separation of the blastomeres, with the divisions being limited to the nonyolked portion of the egg. Synonym: incomplete cleavage. (05 Mar 2000) |
| phosphoroclastic cleavage | <biochemistry> This reaction is an analogue to hydrolysis, except here a molecule is cleaved with phosphate as the attacking group. (09 Oct 1997) |
| cleavage | <cell biology> The early divisions of the fertilized egg to form blastomeres. The cleavage pattern is radial in some phyla, spiral in others. (18 Nov 1997) |
| cleavage cavity | The cavity in the blastula of a developing embryo. Synonym: blastocoele, cleavage cavity, segmentation cavity. Origin: blasto-+ G. Koilos, hollow (05 Mar 2000) |