| 영문 | cancer chemotherapy | 한글 | 항암화학요법 |
|---|---|---|---|
| 설명 | 화학적 물질을 이용하여 암을 치료하는 것을 말한다. 이때 사용되는 물질을 항암제라고 한다. 이상적인 항암제는 정상적인 세포에는 이상이 없고 단지 암세포에만 치명적인 효과를 나타내어야 한다. 이렇게 하려면 암세포만의 특이한 특성을 이해하고 그곳에만 작용하는 약물을 개발하여야 한다. 최근 대부분의 항암제는 암세포가 정상 세포에 비하여 월등히 증식을 빨리한다는 특성을 이용하고 있다. 증식이 빠르다는 것은 유전정보를 가지고 있는 DNA의 복제가 빠르다는 것을 의미한다. 만약 DNA의 복제를 방해한다면 증식이 아주 빠른 암세포에게는 치명적이지만 영원히 증식을 하지 않는(DNA의 복제가 거의 필요없는)신경세포나 증식이 암세포에 비해서 아주 느린 정상세포에서는 거의 영향을 주지 못한다. 하지만 신체에서도 정상적으로 증식이 암세포와 비슷한 수준으로 일어나는 세포가 있는데 그것은 머리카락을 만드는 모낭세포와 소화관의 점막을 이루는 세포와 혈액의 세포를 만드는 골수 세포이다. 그러므로 항암제를 사용할 경우 이런 세포가 암세포와 마찬가지로 치명적인 영향을 입을 것은 당연하다(그래서 항암제 치료시엔 머리가 빠지고 소화불량이 잘온다). |
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| CEA | Carcino-Embryonic Antigen [HP 1825-6] ; Oncofetal Antigens ; Glycopro... |
|---|---|
| CC | calcaneal-cuboid; calcium cyclamate; cardiac catheterization; cardiac contusion; cardiac cycle; card... |
| ICR | [distance between] iliac crests; Institute for Cancer Research; Institute for Cancer Research [mouse... |
| MBC | male breast cancer; maximal bladder capacity; maximal breathing capacity; metastatic breast cancer; ... |
| ATL | Adult T cell Lymphoma |
| T-cell lymphoma | A cancer of the immune system that appears in the skin; also called mycosis fungoides. (12 Dec 1998) |
|---|---|
| T-cell-rich, B-cell lymphoma | <tumour> A B-cell lymphoma in which more than 90% of the cells are of T-cell origin, masking the large cells that form the neoplastic B-cell component. See: adult T-cell lymphoma. (05 Mar 2000) |
| extra nodal lymphoma | <oncology, tumour> Literally outside the lymph nodes, but exhibiting the characteristics of lymph node cancer. A term used to describe the extent and site of disease. (27 Sep 1997) |
| Ki-1+ lymphoma | <tumour> A form of lymphoma characterised by anaplasia of cells, sinusoidal growth, and immunoreactivity with CD30 (Ki-1 or Ber-H2). Synonym: Ki-1+ lymphoma. (05 Mar 2000) |
| follicular lymphoma | <tumour> A malignant lymphoma arising from lymphoid follicular B-cells which may be small or large, growing in a nodular pattern. Synonym: follicular lymphoma, giant follicular lymphoblastoma. (05 Mar 2000) |
| follicular predominantly large cell lymphoma | <tumour> A B-cell lymphoma of intermediate malignancy. (05 Mar 2000) |
| follicular predominantly small cleaved cell lymphoma | <tumour> A B-cell lymphoma with nodular or diffuse lymph node or bone marrow involvement by large lymphoid cells. Synonym: follicular predominantly small cleaved cell lymphoma, nodular histiocytic lymphoma. (05 Mar 2000) |
| large cell lymphoma | <oncology, tumour> Highly malignant group of tumours arising from transformed lymphocytes or myeloid precursors. Cell of origin often obscure. (18 Nov 1997) |
| Lennert's lymphoma | <tumour> Malignant lymphoma with a high proportion of diffusely scattered epithelioid cells, tonsillar involvement, and an unpredictable course. Synonym: Lennert's lesion. (05 Mar 2000) |
| lymphoblastic lymphoma | <tumour> A diffuse lymphoma in children, with supradiaphragmatic distribution and T lymphocytes having convoluted nuclei; many patients develop acute lymphoblastic leukaemia. (05 Mar 2000) |
| lymphocytic lymphoma | <oncology, tumour> A cancer of lymphatic tissues, the tumour cells are mostly abnormal lymphocytes. (13 Nov 1997) |
| lymphoma | <oncology, tumour> Malignant tumour of lymphoblasts derived from B lymphocytes. most commonly affects children in tropical Africa: both Epstein Barr virus and immunosuppression due to malarial infection are involved. (18 Nov 1997) |
| lymphoma, aids-related | B-cell lymphoid tumours that occur in association with aids. Patients often present with an advanced stage of disease and highly malignant subtypes including burkitt lymphoma, immunoblastic large-cell lymphoma, small non-cleaved-cell lymphoma and diffuse large-cell lymphoma. The tumours are often disseminated in unusual extranodal sites and chromosomal abnormalities are frequently present. It is likely that polyclonal B-cell lymphoproliferation in aids is a complex result of ebv infection, HIV antigenic stimulation, and T-cell-dependent HIV activation. (12 Dec 1998) |
| lymphoma, B-cell | A group of heterogeneous lymphoid tumours generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes. (12 Dec 1998) |
| lymphoma, diffuse | Malignant lymphoma in which neoplastic cells diffusely infiltrate the entire lymph node without any definite organised pattern. Patients whose lymphomas present a diffuse pattern generally have a more unfavorable survival outlook than those presenting with a follicular or nodular pattern. (12 Dec 1998) |